1. PGO PROF DEIARY KADER
Research/Education War Trauma
Elective
Postgraduate Orthopaedics
KNEE
RECON/TKR,HTO,UNI,REVISION
Professor Deiary F Kader
Knee Surgeon
Deputy Medical Director (SW London Elective Orthopaedic Centre)
President of BOSTAA ( British Sports Surgeons)
Chairman of NGMV charity
War Trauma Reconstruction Surgeon ICRC/Swisscross
CHARITY
Life Academy
2. PGO PROF DEIARY KADER
• Evidence based non operative treatment of OA —Post operative Mx of TKR
• Why TKR have different implant materials in the femur and tibia
• Which knee prosthesis and why?
• Flexion extension gab balance
• When to operate on PFJ pain if at all
• Principles of PFJR?
• Catastrophic wear- in TKR how to prevent?
• The role of computer navigation/ Robotics in TKR
• Coronal plane sequential ligament release in TKR
• Uni knees indications. Osteotomy cut off age.
• Do you resurface the patella?
• How does changing slop in osteotomy affect load transmission?
• Which HTO-- open or close
• PCL retaining or substituting and why
• What are the technical difficulties in converting Uni to TKR?
• Periprosthetic fracture after TKR approach and management
• Poly difference in TKR and THR
Questions from the Attendee
?
6. PGO PROF DEIARY KADER
Osteotomy
vs
Unicompartmental replacement?
7. PGO PROF DEIARY KADER
Age
Sex
Activity level
Ligament stability
Deformity
8. PGO PROF DEIARY KADER
Evidence based
None-operative
Treatment for OA?
9. PGO PROF DEIARY KADER
OA Nonoperative treatment
Evidence
Weight loss
Exercise
Patient education
Analgesia, (NSAIDs)
Bracing
Intra-articular (IA) injections. Cochrane reviews
Steroids (better than placebo but not longer than 4wks)
HA more prolonged effect than steroids
PRP????
Stem Cells???
Unloader
brace
10. PGO PROF DEIARY KADER
Indications for Valgus Osteotomy
Unload the medial compartment
Unloading any ligament reconstruction in
patients with a varus thrust
To change the tibial slope in order to
reduce translational forces and improve
AP instability
19. PGO PROF DEIARY KADER
Alignment refers to the
collinearity of the hip, knee, and
ankle.
Joint Orientation
refers to the position of each
articular surface relative to the
axes of the individual limb
segments (tibia/ femur)
20. PGO PROF DEIARY KADER
Mechanical Axis of the Lower Limb
Mechanical axis of the lower
limb 1. 3°varus
4-8 mm medial
24. PGO PROF DEIARY KADER
Fujisawa point
Overcorrection of 3º–5º above the 6º–7º normal valgus angle
62.5% across tibial plateau from medial side
31. PGO PROF DEIARY KADER
Proximal or High Tibial Osteotomy (HTO)
The IDEAL candidate for HTO
Age <65 years
Isolated medial OA/Intact Ligaments
Non-Smoker
BMI<30
Almost Full ROM >120°
Less than 5° FFD knee
Patients should be
Able to use crutches
Have no major varicose veins
No peripheral vascular disease
32. PGO PROF DEIARY KADER
The International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine
34. PGO PROF DEIARY KADER
Lateral closed-wedge high tibial osteotomies have
been the treatment of choice since 1965
(Coventry, 1965).
35. PGO PROF DEIARY KADER
Fibular osteotomy, Separating tibiofibular joint
Contracture of the patellar tendon, patellar baja
leg shortening
Nerve injuries
Varus laxity (loose LCL)
TKR is harder
High Tibial Osteotomy with a Calibrated Osteotomy Guide, Rigid Internal Fixation, and
Early Motion. Long-Term Follow-up*
ANNETTE BILLINGS, M.D.†; DAVID F. SCOTT, M.D.‡; MARCELO P. CAMARGO, M.D.§; AARON A.
HOFMANN, M.D.§, SALT LAKE CITY, UTAHJ
Bone Joint Surg Am, 2000 Jan
Closed wedge HTO
Disadvantages
36. PGO PROF DEIARY KADER
OPEN Wedge HTO 1987
The open-wedge high tibial osteotomy gained
recognition after the encouraging reports of
(Hernigou et al., 1987).
Wedges of bone that were obtained from the iliac
crest were inserted into the defect
38. PGO PROF DEIARY KADER
Open Wedge HTO
Advantages
Easier to adjust correction angle
Preserves bone stock (subsequent TKR easier)
Makes MCL tightening easier
Allows LCL or posterolateral -Reconstruction
No risk to peroneal nerve
Less dissection?
39. PGO PROF DEIARY KADER
Open wedge HTO
Disadvantages
Requires a bone graft (substitute, autograft, Allo)
Increased incidence of non or delayed union
Large correction may affect leg lengthening
Loss of fixation and recurrence of varus deformity
Worsens patella Baja
41. PGO PROF DEIARY KADER
RCT 92 pts and 6 years FU
OW-HTO vs CW-HTO
More Complications in open WHTO & more conversion to TKR in closed WHTO
SEPT 2014
42. PGO PROF DEIARY KADER
Distal Femur Osteotomy for Valgus
Malalignment
43. PGO PROF DEIARY KADER
Coventry report
Outcome
5-year survival of 88%
10-year survival of 66%
However the 5-year survival was reduced to
38% if under-corrected or overweight
47. PGO PROF DEIARY KADER
What are the
Biomechanical aims of
TKR?
48. PGO PROF DEIARY KADER
The Primary Aim of TKR
Restoring neutral mechanical axis of 0 (+/- 3Âş)
Balancing the flexion/extension gap (ER of FC)
Preserving the joint line height
Balancing Ligaments ( 2-3 mm play)
Restoring normal joint alignment and Q angle
➢Joint line perpendicular to the Mech axis
60. PGO PROF DEIARY KADER
PCL retaining (CR)
Provides least constraint
Less forces at the interface
Preserves proprioceptive fibres (intact PCL)
Greater stability during stair climbing
(quadriceps strength)
Less risk of condylar fracture
61. PGO PROF DEIARY KADER
PCL retaining (CR) 2
Fewer patella complications
Preserve bone stock on the femoral side
Better kinematics
Avoids the tibial post–cam impingement
Ease of management of supracondylar fracture
(plate/nail)
62. PGO PROF DEIARY KADER
PCL retaining (CR)
Disadvantages
Less conforming surfaces to allow roll-back
Slide/shear stress causes poly delamination
Technically difficult to balance
Late PCL dysfunction
POSTGRAD ORTH Deiary Kader
63. PGO PROF DEIARY KADER
PCL substitution/sacrificing
Advantages
Higher degree of flexion
Less joint line sensitive (Restored within 8-9mm, Figgie)
Congruent joint surfaces reduces wear
Facilitates deformity correction
Superior and more reproducible kinematics
Technically easier than CR
64. PGO PROF DEIARY KADER
PCL substitution/sacrificing
PCL histologically and kinematically abnormal
The cam-post mechanism improves AP stability
Provides a degree of VVC
Conforming surfaces allowing roll-back
No component slide
65. PGO PROF DEIARY KADER
PCL substitution/sacrificing
Disadvantages
High stresses at fixation interface
Femoral bone loss/fracture
Tibial peg increases wear
Post dislocation
3X greater joint line alteration than CR
Patella clunk/ crunch syndrome
67. PGO PROF DEIARY KADER
Indications for PCL Sacrificing Implants
Previous patellectomy
Rheumatoid arthritis
Stiff knee in post-traumatic arthritis
Previous high tibial osteotomy (HTO)
Large deformity, over-released PCL
68. PGO PROF DEIARY KADER
Summary
Both CR & PS knees work very well
Long term outcome comparable
One design wont fit all
PS knees outcome is more predictable
We should be able to do both when it is
indicated POSTGRAD ORTH Deiary Kader
76. PGO PROF DEIARY KADER
Valgus Knee
Posterior capsule
LCL release
Flexion and extension tightness
77. PGO PROF DEIARY KADER
Tight in Flexion
Tight in Extension
Valgus Knee
78. PGO PROF DEIARY KADER
Medial release for varus knee
Osteophytes excision
Deep MCL to posteromedial corner
Semimembranosus aponeurosis
Superficial MCL
PCL
Pes anserinus insertion
79. PGO PROF DEIARY KADER
What are the problems
associated with valgus
knees
80. PGO PROF DEIARY KADER
Valgus knee
Multiple problems associated with valgus knees
Soft-tissue abnormality
Bony deficiencies — acquired or pre-existing
Patella subluxation
Lateral capsule and ligament contracture
PCL dysfunctional in severe valgus
Distal femoral rotational deformity with externally
rotated epicondylar axis up to 10°.
81. PGO PROF DEIARY KADER
Soft-tissue release in valgus knees
Osteophyte excision
Lateral patellofemoral ligament (LPFL) release
Release posterolateral capsule off the tibia
Sacrifice PCL in moderate-severe valgus.
Flexion and extension tightness
Release (or pie-crust) lateral collateral ligament (LCL) from the femur.
Flexion tightness
Release Popliteus
Extension tightness
Release (or pie-crust) the iliotibial band at Gerdy’s tubercle
87. PGO PROF DEIARY KADER
50% of Uni knees had a significant bone defect
88. PGO PROF DEIARY KADER
Post op Mx of TKR
Pre-operative patient education reduces length of stay after knee joint arthroplasty.
Jones S, Alnaib M, Kokkinakis M, Wilkinson M, St Clair Gibson A, Kader D.
Ann R Coll Surg Engl. 2011 Jan;93(1):71-5.
PMID: 21418755 [PubMed - indexed for MEDLINE] Free PMC Article
90. PGO PROF DEIARY KADER
Technical Considerations in TKR
How would you determine the rotation
of the femoral component?
91. PGO PROF DEIARY KADER
Femoral Component
What is the optimal external rotation ?
Suggesting that 2–5° of external rotation is the optimal
position
referenced off the posterior condylar axis
Kim et al. (2014)
LATERAL
92. PGO PROF DEIARY KADER
Rotational alignment of the femoral component
Anatomical landmarks for reference:
Epicondylar axis
Posterior condylar axis
Anteroposterior axis ( Whiteside’s line)
The ant cortex of the femur
94. PGO PROF DEIARY KADER
1-The epicondylar axis
Problems
Difficult to identify
Misuse of the surgical epicondylar axis rather
than the Anatomic one
95. PGO PROF DEIARY KADER
2-The posterior condylar axis
Problems
Inaccurate in severe arthritis
Anatomy of the femur varies
Gender variation
Valgus knee hypoplastic LFC
Varus knee MFC larger
96. PGO PROF DEIARY KADER
3-Anteroposterior (AP) axis
The line deepest part of the trochlear to the Centre of the
intercondylar notch posteriorly
Difficult to Identify
In trochlear dysplasia or destructive arthritis or deformity
Whiteside’s line
97. PGO PROF DEIARY KADER
4- The Anterior Femoral Cortical Line
Dr Mervyn Cross
98. PGO PROF DEIARY KADER
Tibial Tray Rotation
Medial border of the tib tub
Medial 1/3 of the tibial tubercle
Middle of the tibial tubercle
Patellar tendon
PCL attachment
Transverse axis of the tibia
Posterior condylar line (tibia)
Mid-sulcus of the tibial spine
Malleolar axis
The second metatarsal
Reference from the femur
99. PGO PROF DEIARY KADER
What if the Femoral
component internally rotated?
100. PGO PROF DEIARY KADER
What if the FC internally rotated
➢Asymmetric flexion gap
➢Shift into valgus alignment with flexion
➢Increase in Q angle
➢Patella mal-tracking/Instability
➢Severe patellar wear if resurfaced
➢Asymmetric tibial component load
101. PGO PROF DEIARY KADER
The role of Computer Navigation
& Robotics in TKR
102. PGO PROF DEIARY KADER
The Knee is a Modified Hinge Joint
Six degrees of freedom
Varus/valgus
Flexion/extension
Internal/external rotation
Medial/lateral translation
Proximal/distal placement
Anterior/posterior translation).
103. PGO PROF DEIARY KADER
Accuracy in component placement
For Each of these DOF there are 3 outcomes.
In the coronal plane for each component:-
valgus, varus, and neutral alignments.
6x3=18
for the 3 components Femur, tibia, patella there is
18x18x18 =5832 possible different
combinations
Excluding variations in the degree of abnormality (for
example, 2°,4°,or 6°of varus deformity)
104. PGO PROF DEIARY KADER
Navigated Knee Replacement
Computer assisted knee surgery
Computer Assisted Orthopaedic Surgery
CAOS
Coronal malalignment of more than 3°
has been shown to cause premature implant
failure
Significant errors in mechanical axis of > 3°
occur in at least 10% of TKAs, including those
performed by experienced surgeons
107. PGO PROF DEIARY KADER
What is “Robotic” Navigation?
Robotic Surgery- NAVIO- Smith+Nephew
108. PGO PROF DEIARY KADER
What is the NAVIO?
Infrared Camera
and Reflective Arrays
Handheld
Robotic Tool
Surgeon Controlled
Interface
Portable Cart
Burr Motor
Monitor
110. PGO PROF DEIARY KADER
The NAVIO Basics
Exposure Control - Continually adjusts
exposure of the bur beyond a static guard
to modulate cutting.
Speed Control - Continually varies speed
of a fully exposed bur to modulate cutting
(static guard is removed).
q Robotic Driver
q Tracker Array
q Calibration
q Burr Selection Size
q Burr Selection Mode
HANDPIECE
111. PGO PROF DEIARY KADER
Challenges with adopting navigation
➢The tools -expensive and cumbersome
➢They frequently introduce extra surgical steps
➢Increased operative time (25%)
➢The alignment goals often sought by navigation
programs have been called into question.
➢There is virtually no evidence that the use of CAOS
techniques leads to improved clinical outcomes.
112. PGO PROF DEIARY KADER
Challenges
Capital Cost
Training (Surgeon and Theatre Staff)
Additional Trauma due to Pin Insertion
Lengthens Operation Duration
Does Not Account for soft tissue
Surgeon / Assistant Positioning
Limited Implant Compatibility
Benefits
Accuracy in Operative Planning
Planning Multiple Scenario
Enhanced Cut Precision
Bone Conservation / Consistency
Real-time Assessment of Balance
Medico-legal Record-keeping
Robotics Pros and Cones
113. PGO PROF DEIARY KADER
113
Would you resurface
the Patella during TKR?
116. PGO PROF DEIARY KADER
Decision
making process
Knee specific Patient Reported Outcome
Measures (PROMs) naturally assume priority
essential to consider other factors such as
1) Re-operation rate,
2) Patient quality of life and inconvenience
3) Cost-effectiveness, Implant cost and time
4) The burden of secondary patella resurfacing
5) Influence of implant design,
6) Surgical risks, Surgeons’ learning curve
7) The fate of the remaining patella articular
cartilage when not resurfaced.
117. PGO PROF DEIARY KADER
Factors to Consider
PPR
Resurfacing
PPNR
Non-
resurface NOTE
Knee specific (PROMs) comparable
Re-operation rate 0.8-2.3% 3%-6.5%
All cause revision 6.3%-10.6% 8.2%-14.7%
Re-operation rate for anterior knee
pain 1% 4.6%
Absolute risk reduction after
Resurfacing 4%-4.6%
Patient quality of life
QALY gain
0.64 comparable
Patient inconvenience (Admission for
SPR) 28-29 months
Cost-effectiveness, Intra-operative
time
ÂŁ104 cheaper
3 minutes
more±
Outcome of secondary patella
resurfacing (SPR)
44-50%
benefit
COMPLICATIONS ARE HISTORIC
PFC Sigma PS knee revision rate 2.6% 10y 4.37% 10y
Attune PS 2.93% 3.85%
4.47% 10y-
•Equivocal clinical outcomes
•Lower re-operation rates
•Economic viability
•Low risk of complications
118. PGO PROF DEIARY KADER
Titanium or Cobalt Chrome
for Tibial component?
120. PGO PROF DEIARY KADER
Materials in TKR
Material Elastic Modulus
Stiffness
Stainless Steel
230 GPa
Cobalt-Chrome alloy 220 Giga Pascal
Ti6Al4V
110 GPa
Cortical Bone
20 GPa
Trabecular Bone 1.0 GPa
PMMA Cement
4 GPa
121. PGO PROF DEIARY KADER
Ti or CoCr for tibia
Titanium alloys have great corrosion resistance,
inert biomaterial, fast bone bonding and reduce
stress shielding
Titanium alloy knees generated significantly more metallic debris more
toxic to the surrounding tissue
CoCr knees more polyethylene debris and more likely to release
inflammatory cytokines causing osteolysis
125. PGO PROF DEIARY KADER
Investigations
Plain weight-bearing X-ray
Bloods (including WCC, ESR and CRP – 16S Ribosomal)
Knee aspiration
Fluoroscopic alignment check
CT scan to check rotation
Long-leg films to assess the overall alignment
Bone scan (not helpful until a year after the index
procedure), white cell-labelled bone scan
SPECT-CT an option to detect loosening / infection and
highlight areas of maximal activity.
The Synovasure™ Alpha Defensin Test
127. PGO PROF DEIARY KADER
Polyethylen Wear
What are the factors that determine poly
wear??
128. PGO PROF DEIARY KADER
Polyethylen Wear
• Patient factors: age, size and activity level
• Surgical factors: alignment, rotation, cementing, balancing
• Implant factors:
• Poly thickness
• Material, property and polymerization
• Manufacturing method: compression moulding preferred to machined
component
• Sterilization method: avoiding gamma radiation in air
• Cross-linking: moderately/highly cross-linked polyethylene – may
offer improved resistance in the knee.
• Packing vacuum pack is still in date (free radicals)
129. PGO PROF DEIARY KADER
Causes of catastrophic wear
PE thickness <8mm
articular surface design- flat tibial PE
Kinematics Varus alignment & dyskinetic sliding
PE sterilization O2 rich environment leads to
subsurface delamination
pitting
fatigue cracking
PE machining use direct-compression molding of PE
134. PGO PROF DEIARY KADER
Planning
parameters to be considered
➢ Anatomic variation
➢ Implant fixation
➢ Extensor mechanism integrity
➢ Patellar
➢ Joint line height
➢ Tibial or femoral bowing
➢ Narrow intramedullary canal
➢ Ipsilateral hip prosthesis
135. PGO PROF DEIARY KADER
The success of revision depends
âś“ Identifying the cause of failure
âś“ Thorough preoperative planning
âś“ Precise surgical technique
âś“ Reconstruction of the leg axis
Good component design and availability of
diverse implant options
136. PGO PROF DEIARY KADER
Revision Knee
Technical Problems
➢ Under sizing Implant
➢ Bone defects
➢ Flexion & Extension Gap Mismatch
➢ Sold Stems causing pain
➢ Stems impacting/causing stress riser on cortex
➢ Stem position not compatible with Component position
➢ Inadequate Component stability on the Epiphysis
➢ Metal sensitivity
143. PGO PROF DEIARY KADER
Processing methods for XLPE
acetabular liner and tibial insert
for total hip and knee
arthroplasty
HXLPE weakens the
mechanical properties,
including strength and
fatigue resistance and
reduced fracture
toughness
But reduces volumetric wear
144. PGO PROF DEIARY KADER
chemical reaction or
radiation energy.
Polymer chains
145. PGO PROF DEIARY KADER
KNEE
TKR is less constrained
less conformed
high contact stress
High compressive stresses 3x higher
High Sheering force 2X higher
Subjected to fatigue wear (delamination)
150. PGO PROF DEIARY KADER
What is the Definition of
Peri-prosthetic joint Infection
International Consensus Meeting in 2013 as:
Musculoskeletal Infection Society
A sinus tract communicating with the joint
OR
2 positive cultures with identical organisms
OR
3-4 of the following minor criteria:
Elevated CRP and ESR
Single positive culture
Elevated synovial fluid WCC —1,100 to 4,000 cells/µL
Elevated synovial fluid PMN 64%-69%
Presence of purulence in the affected joint
151. PGO PROF DEIARY KADER
What is the Definition of
Peri-prosthetic joint Infection
International Consensus Meeting in 2018 as:
Musculoskeletal Infection Society
A sinus tract communicating with the joint
OR
2 positive cultures with identical organisms
OR
3-4 of the following minor criteria:
Elevated CRP > 1mg/dl, D-dimer >860 ng/ml and ESR > 30mm/h
Elevated synovial fluid WCC —> 3000 cells/µL
– Alpha-defesin >1 signal to cutoff ration (human neutrophil peptide)
– Leukocyte Esterase ++ (an enzyme produced by leukocytes)
Serum interleukin-6
152. PGO PROF DEIARY KADER
Infection
Revision for
Infection (22%)
153. PGO PROF DEIARY KADER
Commonly used CCK in UK
PFC Sigma
TC3 (DePuy)
Triathlon TS
(Stryker)
Legion
Smith &
Nephew
Vanguard SSK
(Biomet)
NexGen
(Zimmer)
154. PGO PROF DEIARY KADER
Mal-Alignment
Places mechanical and shear stresses on the
bearing surfaces
bone/prosthesis interfaces
ALSO
•Changes the forces going through the soft-tissue envelope
155. PGO PROF DEIARY KADER
Implant malalignment has been reported to be
• Most influential factors in determining the long-term outcomes
• The primary reason for revision in 7-10 % of TKAs (Schroer et al. 2013)
• Linked to decreased implant survival (Ritter et al. 2011)
• Inferior patient-reported outcomes (Choong et al. 2009, Longstaff et al. 2009).
162. PGO PROF DEIARY KADER
Patellofemoral maltracking
DO NOT
Overstuff the patella.
Oversize the femoral component
Internally rotate of the tibial component (increases the
Q angle)
Avoid an excessive valgus angle
Avoid raising the joint line
POSTGRAD ORTH Deiary Kader
163. PGO PROF DEIARY KADER
14 Causes for Patellar problems
7 in the Femur: IR, ER, medial, Valgus, Ant,
Post, oversized
4 in the Tibia: IR, Medial, Valgus, Ant
3 in the Patella: under-resection, Over-resection,
lateral
166. PGO PROF DEIARY KADER
PFJ OA
kneeling, squatting, climbing stairs, and
getting up from a low chair.
More subtle than knee OA
Swelling para-patella
Crepitus anterior knee
169. PGO PROF DEIARY KADER
PFJ OA
PFJ replacement or TKR?
1. Age
2. Other compartments
3. Implant failure rate
170. PGO PROF DEIARY KADER
PFJR
Revision rate 9% in 5 years
revision rate is 19% in 10 years
why?
Failure to regard as a Soft tissue procedure
Maltracking
Catching
Subluxations
171. PGO PROF DEIARY KADER
Priciples
Understanding the pathology and Dx
Is there instability?
Meticulous surgical technique
Soft tissue balance/lateral release
External rotation of the trochlea
Avoid over/understuffing the patella
Implant design use on-lay not inlay
AVON Stryker
FPV Vialli Wright medical
Journey by S&N