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Drug testing on `heart-on-a-
chip' gets a step closer
Brought to you by
The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
Contd..
Researchers, including one of Indian origin, have created a
`heart-on-a-chip' loaded with human cardiac muscle cells
that mimic the real organ to serve as a novel tool to
screen medicines. Researchers developed a network of
pulsating cardiac muscle cells housed in an inch-long
silicone device that effectively models human heart tissue,
and they have demonstrated the viability of this system as
a drug-screening tool by testing it with cardiovascular
medications.
This organ-on-a-chip represents a major step forward in
the development of accurate, faster methods of testing
for drug toxicity , researchers said. “Ultimately , these
chips could replace the use of animals to screen drugs for
safety and efficacy ,“ said professor Kevin Healy from the
University of California, Berkeley .
Brought to you by
The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
Contd..
The authors noted a high failure rate associated with the
use of non-human animal models to predict human
reactions to new drugs.
“It takes about £5 billion on average to develop a drug,
and 60% of that figure comes from upfront costs in the
research and development phase. Using a well-designed
model of a human organ could significantly cut the cost
and time of bringing a new drug to market,“ said Healy .
The heart cells were derived from human-induced
pluripotent stem cells, the adult stem cells that can be
coaxed to become many different types of tissue.
Researchers designed their heart-on-a-chip so that its 3D
structure would be comparable to the geometry and
spacing of connective tissue fibre in a human heart.
Brought to you by
The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
This platform has been started by Parveen Kumar Chadha with
the vision that nobody should suffer the way he has suffered
because of lack and improper healthcare facilities in India. We
need lots of funds manpower etc. to make this vision a reality
please contact us. Join us as a member for a noble cause.
Brought to you by
The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
Our views have increased the mark of the
92,000
 Thank you viewers
 Looking forward for franchise, collaboration, partners.
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Drug testing on `heart on-a-chip' gets a step closer

  • 1. Drug testing on `heart-on-a- chip' gets a step closer Brought to you by The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
  • 2. Contd.. Researchers, including one of Indian origin, have created a `heart-on-a-chip' loaded with human cardiac muscle cells that mimic the real organ to serve as a novel tool to screen medicines. Researchers developed a network of pulsating cardiac muscle cells housed in an inch-long silicone device that effectively models human heart tissue, and they have demonstrated the viability of this system as a drug-screening tool by testing it with cardiovascular medications. This organ-on-a-chip represents a major step forward in the development of accurate, faster methods of testing for drug toxicity , researchers said. “Ultimately , these chips could replace the use of animals to screen drugs for safety and efficacy ,“ said professor Kevin Healy from the University of California, Berkeley . Brought to you by The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
  • 3. Contd.. The authors noted a high failure rate associated with the use of non-human animal models to predict human reactions to new drugs. “It takes about £5 billion on average to develop a drug, and 60% of that figure comes from upfront costs in the research and development phase. Using a well-designed model of a human organ could significantly cut the cost and time of bringing a new drug to market,“ said Healy . The heart cells were derived from human-induced pluripotent stem cells, the adult stem cells that can be coaxed to become many different types of tissue. Researchers designed their heart-on-a-chip so that its 3D structure would be comparable to the geometry and spacing of connective tissue fibre in a human heart. Brought to you by The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
  • 4. This platform has been started by Parveen Kumar Chadha with the vision that nobody should suffer the way he has suffered because of lack and improper healthcare facilities in India. We need lots of funds manpower etc. to make this vision a reality please contact us. Join us as a member for a noble cause. Brought to you by The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-
  • 5. Our views have increased the mark of the 92,000  Thank you viewers  Looking forward for franchise, collaboration, partners. Brought to you by The Nurses and attendants staff we provide for your healthy recovery for bookings Contact Us:-