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VM 352
Prof. Modesta Makungu
Dept. of Veterinary Surgery and
Theriogenology
2022
OTHER IMAGING
TECHNIQUES
Fiberoptic endoscopy
• Is a non invasive technique for evaluating the
lumen and mucosa of the gastrointestinal tract
• A knowledge of the normal appearance of various
luminal surfaces and the underlying anatomy is
essential
• Requires general anaesthesia
• Many git lesions have a polymorphic appearance.
Therefore biopsy is mandatory for definitive
diagnosis
Fiberoptic endoscope
Indications
• Oesophagus
-Oesophagitis
-Foreign body obstruction
-Neoplasia
-Stricture
-Gastroeosophageal intussusception
-Hiatal hernia
• Stomach
-Acute and chronic gastritis
-Gastric ulceration
-Foreign body
-Neoplasia
-Pyloric sternosis
-Hypertrophic gastropathies
• Small intestines
-Ulceration
-Chronic inflammatory disorders
-Foreign body
-Neoplasia
• Colon
-Colitis
-Neoplasia
-Ileocolic intussusception
Endoscopic procedure
• The animal must be fasted for 24 hours
- Allow ingesta to pass from the stomach and
upper intestine
- Preparation for general anaesthesia
• For upper digestive tract
- Animal should be in left lateral recumbency
(releases the pylorus and pyloroduodenal angle
from the weight of the viscera)
• General anaesthesia
• Moderate insufflation
Endoscopic procedure
• A colonoscopy is also performed on an
animal in left lateral recumbency,
• Avoids accumulation of liquid within the
transverse colon and ease the passage of
the endoscope beyond the splenic flexure
of the colon
• Moderate insufflation
Normal appearance
• Oesophagus
Pale pink in colour Ulcerative oesophagitis
Oesophageal foreign body
Oesophageal stricture
Normal oesophagus
• Stomach
Normal gastric mucosa Haemorrhagic gastritis
• Colon
Normal colon Colitis
PRINCIPLES OF COMPUTED
TOMOGRAPHY
Computed tomography (CT):
• Is the process of production of cross
sectional images using X-rays and
computers
• Advantages of CT over conventional X-ray
techniques
- Superior soft tissue differentiation
- No superimposition of overlying structures
CT
• Tomogram – an image of a slice or cut
through a body part
• CT, MRI and ultrasound are all tomograms
CT Physics
• Heavy duty x-ray tube rotates around the
patient
• Multiple x-ray beam projections are made
through the patient
CT Physics
• The x-rays are attenuated by the tissues
• The remnant radiation strikes a circular or
curvilinear array of detectors
CT Physics
• The detectors when stimulated convert the
radiation into an electric signal
• The computer processes all the digital
signals in a complex algorithm
• A transverse (axial) image is reconstructed
and displayed
CT Physics
• Image is composed of pixel
• Pixel = 2D square
• Voxel = 3D block of tissue
• Each pixel represents attenuation in a
voxel
Image processing
• The amount of remnant radiation passing
through the voxel is dependant on the
attenuation of that voxel
Image processing
• Each pixel is given a certain grey scale
• Grey scale = attenuation of voxel of tissue
• Grey scale = CT number = HOUNSFIELD
UNITS
Image processing
• CT number of water = 0
• All other tissues are
compared to water and
assigned a CT number
(from -1000 to +4000)
• The higher the CT number the brighter (or
denser) the pixel
Image processing
Advantages of CT
• Excellent contrast resolution
• Cross sectional anatomy avoids super
imposition
• Rapid image acquisition
• Post-acquisition digital manipulation
including multiplanar and 3D
reconstruction
Disadvantage of CT
• Radiation dose
Image Display;
• Multiplanar reformatting
• Maximum Intensity Projection
• Surface Shaded Display
• Volume Rendering Technic
Components of a CT scanner
Clinical applications
• Head
- Fractures
- Tumours
• Spine
- Disc prolapses
- Fractures
- Neoplasia
• Thorax
• Abdomen
• Joints
Principles of magnetic resonance
imaging (MRI)
Advantages of MRI compared to other
imaging modalities
• Excellent soft tissue contrast
• Cross sectional images
• No ionizing radiation
NB: Ideal for central nervous system imaging
• The patient is placed in a high magnetic field
• A radiofrequency wave is applied and which
interacts with protons in the patient
• The radiofrequency wave is turned off which
results in a signal being emitted from patient
• The signal is received by an antenna and the
image is reconstructed by computer
• The RF pulse frequencies are varied in duration
and strength to produce T1 and T2 weighted
images
T2 T1
Imaging planes
• Sagittal
• Transverse
• Dorsal
Hydrocephalus
Courtesy University of Pretoria
Meningioma
Precautions
Disadvantages
• General anaesthesia
• Limitation use in patients with
- Ferrous implants
Can cause artefacts and can be pulled out
of patient
Nuclear Medicine
Scintigraphy
• Diagnose abnormal function
• Detect diseases that alter the physiology
Scintigraphy
• Some atoms have nuclei with excess
energy = radionuclide
• Abnormally excited state
• Undergoes radioactive decay to become
more stable
• Emits particles and energy (β, α, ɤ rays)
Scintigraphy
• Radionuclide bound to a localising agent =
radiopharmaceutical
• Injected IV
• Localises in a particular body region
• Undergoes radioactive decay
• Emits gamma rays = imaged with gamma
camera
Radioactive decay
• Rate of decay specific for each
radionuclide
• Expressed as radioactive half-life
• Half life = time required for 50% of
radioactivity to decay
• Becquerel = 1 disintegration per second
• Curie = 3.7 x 1010 disintegration per
second
99m-Technetium
• Most commonly used
• Formed by decay of Molybdenum
• Easily generated
• Binds to various RPs
• Half-life = 6 hours
• Emits gamma rays
• 140 keV photon is readily detectable
Radiopharmaceutical kits
• Sterile reaction vial with non-radioactive
chemical
Gamma Camera
• Scintillation detector
• Counts
• Detects position
Gamma Camera
• Collimator
• NaI scintillation crystal
• Photomultiplier (PM) tubes
• Positional circuitry
• Pulse height analyzer
• Computer
Image evaluation
• Decreased RP uptake = photopaenia “cold
spot”
• Increased RP uptake = “hot spot”
• Always compare to opposite limb at the
same time
Clinical application
• Bone
• Thyroid
• Portosystemic shunts
FLUOROSCOPY
Fluoroscopy
• Is a specialized type of x-ray examination
used primarily to visualize the continuous
movement of internal structures
• Provides a real time radiographic viewing of
moving anatomic structures
• Uses an X-ray tube, image intensifier and
television viewing system
Indications
• For assessment of motility and function of
the pharynx, oesophagus, stomach and
bowel
• Evaluation of respiratory function
- tracheal collapse
- bronchial collapse
- observe diaphragmatic movement
• To direct internal organs biopsies and
aspirates e.g. lung
Fluoroscopic system consists of:
• X-ray tube
• Image intensifier tube
• Television viewing system
NB: Most fluoroscopic systems
have the X-ray tube located
under the table
X-ray tube
• Generation of X-rays
Image intensifier tube
• Has an input and output fluorescent screens
• Screens contains crystals
• Converts x-ray image;
- into light image,
- then to an electron image
- and finally back to a light
image of diminished size
and increased brightness
• The image is viewed through closed-circuit
television
• Permanent records of fluoroscopic images
can be recorded on x-ray films (spot film) or
video tape
Radiation exposure
• Radiology personnel involved in fluoroscopy
receive higher exposures because of the long
fluoroscopic times that are used
• Radiation exposure to personnel is the major
disadvantage of doing fluoroscopy in animals
• Therefore fluoroscopic studies should used only
when specifically indicated
• Should be performed by a veterinary radiologist or
similarly trained person who is knowledgeable
about radiation protection and the equipment

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Other Imaging Techniques.pdf

  • 1. VM 352 Prof. Modesta Makungu Dept. of Veterinary Surgery and Theriogenology 2022 OTHER IMAGING TECHNIQUES
  • 2. Fiberoptic endoscopy • Is a non invasive technique for evaluating the lumen and mucosa of the gastrointestinal tract • A knowledge of the normal appearance of various luminal surfaces and the underlying anatomy is essential • Requires general anaesthesia • Many git lesions have a polymorphic appearance. Therefore biopsy is mandatory for definitive diagnosis
  • 4. Indications • Oesophagus -Oesophagitis -Foreign body obstruction -Neoplasia -Stricture -Gastroeosophageal intussusception -Hiatal hernia
  • 5. • Stomach -Acute and chronic gastritis -Gastric ulceration -Foreign body -Neoplasia -Pyloric sternosis -Hypertrophic gastropathies
  • 6. • Small intestines -Ulceration -Chronic inflammatory disorders -Foreign body -Neoplasia • Colon -Colitis -Neoplasia -Ileocolic intussusception
  • 7. Endoscopic procedure • The animal must be fasted for 24 hours - Allow ingesta to pass from the stomach and upper intestine - Preparation for general anaesthesia • For upper digestive tract - Animal should be in left lateral recumbency (releases the pylorus and pyloroduodenal angle from the weight of the viscera) • General anaesthesia • Moderate insufflation
  • 8. Endoscopic procedure • A colonoscopy is also performed on an animal in left lateral recumbency, • Avoids accumulation of liquid within the transverse colon and ease the passage of the endoscope beyond the splenic flexure of the colon • Moderate insufflation
  • 9. Normal appearance • Oesophagus Pale pink in colour Ulcerative oesophagitis
  • 10. Oesophageal foreign body Oesophageal stricture Normal oesophagus
  • 11. • Stomach Normal gastric mucosa Haemorrhagic gastritis
  • 14. Computed tomography (CT): • Is the process of production of cross sectional images using X-rays and computers • Advantages of CT over conventional X-ray techniques - Superior soft tissue differentiation - No superimposition of overlying structures
  • 15. CT • Tomogram – an image of a slice or cut through a body part • CT, MRI and ultrasound are all tomograms
  • 16. CT Physics • Heavy duty x-ray tube rotates around the patient • Multiple x-ray beam projections are made through the patient
  • 17. CT Physics • The x-rays are attenuated by the tissues • The remnant radiation strikes a circular or curvilinear array of detectors
  • 18. CT Physics • The detectors when stimulated convert the radiation into an electric signal • The computer processes all the digital signals in a complex algorithm • A transverse (axial) image is reconstructed and displayed
  • 19. CT Physics • Image is composed of pixel • Pixel = 2D square • Voxel = 3D block of tissue • Each pixel represents attenuation in a voxel
  • 20.
  • 21. Image processing • The amount of remnant radiation passing through the voxel is dependant on the attenuation of that voxel
  • 22. Image processing • Each pixel is given a certain grey scale • Grey scale = attenuation of voxel of tissue • Grey scale = CT number = HOUNSFIELD UNITS
  • 23. Image processing • CT number of water = 0 • All other tissues are compared to water and assigned a CT number (from -1000 to +4000) • The higher the CT number the brighter (or denser) the pixel
  • 25. Advantages of CT • Excellent contrast resolution • Cross sectional anatomy avoids super imposition • Rapid image acquisition • Post-acquisition digital manipulation including multiplanar and 3D reconstruction
  • 26. Disadvantage of CT • Radiation dose
  • 27. Image Display; • Multiplanar reformatting • Maximum Intensity Projection • Surface Shaded Display • Volume Rendering Technic
  • 28. Components of a CT scanner
  • 29.
  • 30.
  • 31.
  • 32. Clinical applications • Head - Fractures - Tumours • Spine - Disc prolapses - Fractures - Neoplasia • Thorax • Abdomen • Joints
  • 33. Principles of magnetic resonance imaging (MRI)
  • 34. Advantages of MRI compared to other imaging modalities • Excellent soft tissue contrast • Cross sectional images • No ionizing radiation NB: Ideal for central nervous system imaging
  • 35. • The patient is placed in a high magnetic field • A radiofrequency wave is applied and which interacts with protons in the patient • The radiofrequency wave is turned off which results in a signal being emitted from patient • The signal is received by an antenna and the image is reconstructed by computer • The RF pulse frequencies are varied in duration and strength to produce T1 and T2 weighted images
  • 36.
  • 37.
  • 38. T2 T1
  • 39. Imaging planes • Sagittal • Transverse • Dorsal
  • 43. Disadvantages • General anaesthesia • Limitation use in patients with - Ferrous implants Can cause artefacts and can be pulled out of patient
  • 45. Scintigraphy • Diagnose abnormal function • Detect diseases that alter the physiology
  • 46. Scintigraphy • Some atoms have nuclei with excess energy = radionuclide • Abnormally excited state • Undergoes radioactive decay to become more stable • Emits particles and energy (β, α, ɤ rays)
  • 47. Scintigraphy • Radionuclide bound to a localising agent = radiopharmaceutical • Injected IV • Localises in a particular body region • Undergoes radioactive decay • Emits gamma rays = imaged with gamma camera
  • 48.
  • 49. Radioactive decay • Rate of decay specific for each radionuclide • Expressed as radioactive half-life • Half life = time required for 50% of radioactivity to decay • Becquerel = 1 disintegration per second • Curie = 3.7 x 1010 disintegration per second
  • 50. 99m-Technetium • Most commonly used • Formed by decay of Molybdenum • Easily generated • Binds to various RPs • Half-life = 6 hours • Emits gamma rays • 140 keV photon is readily detectable
  • 51. Radiopharmaceutical kits • Sterile reaction vial with non-radioactive chemical
  • 52. Gamma Camera • Scintillation detector • Counts • Detects position
  • 53. Gamma Camera • Collimator • NaI scintillation crystal • Photomultiplier (PM) tubes • Positional circuitry • Pulse height analyzer • Computer
  • 54. Image evaluation • Decreased RP uptake = photopaenia “cold spot” • Increased RP uptake = “hot spot” • Always compare to opposite limb at the same time
  • 55. Clinical application • Bone • Thyroid • Portosystemic shunts
  • 57. Fluoroscopy • Is a specialized type of x-ray examination used primarily to visualize the continuous movement of internal structures • Provides a real time radiographic viewing of moving anatomic structures • Uses an X-ray tube, image intensifier and television viewing system
  • 58. Indications • For assessment of motility and function of the pharynx, oesophagus, stomach and bowel • Evaluation of respiratory function - tracheal collapse - bronchial collapse - observe diaphragmatic movement • To direct internal organs biopsies and aspirates e.g. lung
  • 59. Fluoroscopic system consists of: • X-ray tube • Image intensifier tube • Television viewing system NB: Most fluoroscopic systems have the X-ray tube located under the table
  • 61. Image intensifier tube • Has an input and output fluorescent screens • Screens contains crystals • Converts x-ray image; - into light image, - then to an electron image - and finally back to a light image of diminished size and increased brightness
  • 62. • The image is viewed through closed-circuit television • Permanent records of fluoroscopic images can be recorded on x-ray films (spot film) or video tape
  • 63.
  • 64. Radiation exposure • Radiology personnel involved in fluoroscopy receive higher exposures because of the long fluoroscopic times that are used • Radiation exposure to personnel is the major disadvantage of doing fluoroscopy in animals • Therefore fluoroscopic studies should used only when specifically indicated • Should be performed by a veterinary radiologist or similarly trained person who is knowledgeable about radiation protection and the equipment