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Invited Lectures and Presentations (2000-Present)
Health Effects of Phycotoxins from Harmful Algal Blooms (HABs), Society of Toxicologic
Pathology Annual Symposium, Washington, DC, June 25, 2014
Celiac Disease, Gluten and Immune-mediated Disorders: Challenges and Future Directions.
Continuing Education Course on Immunopathology. International Academy of Toxicologic
Pathology (IATP) Symposium, and the European Society of Toxicologic Pathology (ESTP),
Uppsala, Sweden, September 2011.
Environmental Neurotoxicologic Pathology and the Regulatory Process.
Symposium: Environmental Pathology, XXVIIIth Congress of the International Academy of
Pathology - São Paulo, Brazil. October 2010.
Environmental Toxicological Pathology. 1st Workshop of the Latin American Society of
Toxicologic Pathology (LASTP). University of the State of Sao Paulo, Botucatu, Brazil, October
2010
Food Allergies and Intolerances. Current Knowledge. Faculty of Pharmaceutical Sciences,
Department of Food and Experimental Nutrition, Sao Paulo University, Sao Paulo, Brazil,
October, 2010
The role of toxicological pathology in the regulatory process. Symposium: Role of Toxicological
Pathology on Chemical Risk Assessment. Asociación Latino-Americana de Patología
Toxicológica (ALAPT). Sao Paulo, Brazil, March 2008
Overcoming the challenges faced by the general pathologist conducting developmental
neuropathology studies for toxicology assessment. Chair and Organizer of the Continuing
Education Course: Toxicologic Pathology of the Developing Nervous System. Annual
Symposium of the Society of Toxicologic Pathology, Vancouver, Canada, 2006
Neuropatología Toxicológica del Sistema Nervioso Central en Desarrollo. Profesor Invitado,
Programa de Doctorado en Neurotoxicologia y Psicofarmacología, Universidad de Rovieri i
Virgili, Reus, Tarragona, Spain, June 2005-2007.
Food excitotoxins and glutamate receptors. Symposium on Food Neurotoxins. International
Association of Neurotoxicology, Dresden, Germany, June 2003
Food excitotoxins and glutamate receptors. Symposium on Food Neurotoxins. International
Association of Neurotoxicology, Dresden, Germany, June 2003.
Seafood Toxins: a global problem with new challenges. Spirolides - novel shellfish toxins.
Symposium on Biotoxins. Meeting on Neurobehavioral Methods and Effects in Occupational
and Environmental Health, Brescia, Italy, 2002.
Neurotoxicological Pathology- From Necropsy to Transcriptional Analysis. Section on
Neuroscience Teaching and Education. Soc. For Neuroscience, San Diego, California, USA,
2001.
Neurotoxicological Pathology- From Necropsy to Transcriptional Analysis. Symposium on

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investigative pathology. Dept. of Pathology and Laboratory Medicine. Ottawa University, 2001.
Toxicological Neuropathology from Domoic Acid to Spirolides. The Health Canada Experience.
7th
Canadian Workshop on Harmful Marine Algae. Fishery and Oceans, Pacific Biological
Station, Nanaimo, BC. 2001.
Histopathology, Immunohistochemistry and Transcriptional Analysis of Biomarkers of Neural
Injury, Novel Shellfish Toxins. Int. Neurotoxicology Association. Estoril, Portugal, 2001.
Heart and brain glutamate receptors- a common mechanism for excitotoxicity? XIVth
International Congress of Neuropathology, Birmingham, UK. Sept. 2000.
Glutamate receptors implications for toxicology. Symposium on Glutamate Receptors, National
Research Council, Ottawa, ON. March 2000.
Toxicological pathology at Health Canada. International Symposium, Current Concepts in
Investigative Pathology, Santo Domingo, Dominican Republic. April 2000.
Publications
Pulido OM. Marine Algal Toxins: Seafood Safety, Human Health and Beyond. Oceanography
2014, 2: e111. doi:10.4172/2332-2632.1000e111 (by Invitation)
Olga M Pulido. Chapter 8. Domoic Acid: Biological Effects and Health Implications. In Rossini,
Gian Paolo, ed. Toxins and Biologically Active Compounds from Microalgae. Vol. 2. Biologicl
Effects and Risk Management. Section 2. Impact of Toxic Microalgae and Microalgal Toxins on
Biological Systems. CRC Press, 2014, pp 219-252 (by Invitation)
Pulido O, Zarkadas M, Dubois S, Macisaac K, Cantin I, La Vieille S, Godefroy
S, Rashid M. Clinical features and symptom recovery on a gluten-free diet in Canadian adults
with celiac disease. Can J Gastroenterol. 2013 Aug; 27(8):449-53.
Olga M. Pulido and Santokh Gill. Chapter 35, Food and Toxicologic Pathology: An
Introduction. Haschek and Rousseaux’s Eds., Handbook of Toxicologic Pathology 3e,
VOLUME II – Safety Assessment including Current and Emerging Issues in Toxicologic
Pathology Part 3 – Food and the Environment: Selected Toxic Agents. Elsevier, 2013. pp
1051-1073 (By invitation)
S. Gill, W. Bowers, J. Nakai, I. Chu, D. Moir, A.Yagminas, R. Mueller and O. Pulido. Effects of
Environmentally Relevant Mixtures of Persistent Organic Pollutants on the Developmental
Neurobiology in Rats. Toxicol Pathol 41:38-47,2013
Marion Zarkadas , Sheila Dubois , Krista MacIsaac , Isabelle Cantin, Mohsin Rashid, Karen C.
Roberts, Sébastien La Vieille, Samuel Godefroy, Olga M. Pulido* Living With Celiac Disease
and A Gluten-Free Diet: A Canadian Perspective. J Hum Nutr Diet. 28:10-23, 2012.
Zoë Gillespie, Olga Pulido and Elizabeth Vavasour. Risk Assessment Approaches for
Carcinogenic Food Contaminants. International Food Risk Analysis Journal Volume 1, Issue 1,
Sep 2011
Pulido Olga M. Chapter 1. Immune-mediated adverse reactions to dietary proteins. In Allergen
Management in the Food Industry, Editors: Joyce I. Boye and Samuel Godefroy; John Wiley &
Sons Publishing Co. 2010, pp 3-32. (By invitation)

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Pulido Olga M., Gillespie Z, and Godefroy SB. Chapter 4. The Canadian criteria for the
establishment of new priority food allergens: evidences for the inclusion of mustard and
insufficient evidences for garlic and onion as priority allergens in Canada. In Allergen
Management in the Food Industry, Editors: Joyce I. Boye and Samuel Godefroy; John Wiley &
Sons Publishing Co. 2010, pp 75-130. (By Invitation)
Pulido Olga M. , Gillespie Z, Zarkadas M, Dubois S, Vavasour E, Rashid M, Switzer C,
Godefroy SB. Chapter 6. Introduction of oats in the diet of individuals with
Celiac disease. A systematic review. Adv Food Nutr Res. 2009; 57:235-85 (By invitation).
Pulido OM. Domoic acid toxicologic pathology: a review. Marine Drugs. 2008 May
28; 6(2): 180-219.
Gill SS, Hou Y, Ghane T, Pulido OM. Regional susceptibility to domoic acid in
primary astrocyte cells cultured from the brain stem and hippocampus. Marine Drugs.
2008 Feb 14; 6 (1): 25-38.
Gill S, Barker M, Pulido O. Neuroexcitatory targets in the female reproductive
system of the nonhuman primate (Macaca fascicularis). Toxicol Pathol.
2008; 36(3): 478-84.
Chu I, Bowers WJ, Caldwell D, Nakai J, Wade MG, Yagminas A, Li N, Moir D, El
Abbas L, Håkansson H, Gill S, Mueller R, Pulido O. Toxicological effects of in utero and
lactational exposure of rats to a mixture of environmental contaminants detected in Canadian
Arctic human populations. J Toxicol Environ Health A. Jan; 71(2):93-108, 2008.
Gill S, Veinot J, Kavanagh M, Pulido O. Human heart glutamate receptors – implications for
toxicology, food safety, and drug discovery. Toxicol Pathol. 35(3): 411-7, 2007.
Rashid M, Butzner D, Burrows V, Zarkadas M, Case S, Molloy M, Warren R, Pulido O, Switzer
C. Consumption of pure oats by individuals with celiac disease: a position statement by the
Canadian Celiac Association. Can J Gastroenterology. Oct; 21(10):649-51, 2007.
Morton D, Kemp RK, Francke-Carroll S, Jensen K, McCartney J, Monticello TM,
Perry R, Pulido O, Roome N, Schafer K, Sellers R, Snyder PW. Best practices for reporting
pathology interpretations within GLP toxicology studies. Toxicol Pathol.; 34(6):806-9, 2006.
Ih Chu, Wayne J. Bowers, Don Caldwell, Jamie Nakai, Olga Pulido, Al Yagminas, Michael G.
Wade, David Moir, Santokh Gill, and Rudi Mueller. Toxicological Effects of Gestational and
Lactational Exposure to a Mixture of Persistent Organochlorines in Rats: Systemic Effects.
Toxicol. Sci. 88: 645-655, 2005.
Santokh Gill and Olga Pulido. Distribution of Glutamate Receptors in Peripheral Tissues. In
Glutamate Receptors in Peripheral Tissues, S.Gill & O. Pulido (Eds), Kluwer Academic Plenum
Press, NY, page 3-26, 2005
Olga Pulido, Don Caldwell, Meghan Murphy and Santokh Gill. Chapter 15. Practical
Considerations in Assessing Immunhistopathology in Rodents and Nonhuman Primates. In
Investigative Immunotoxicology, Helen Tryphonas et al (Eds), Tylor & Francis International,
CRC press, USA, p 229, 2005.

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Cooke G.M., Tryphonas H., Pulido O., Caldwell. D., Bondy G.S., Forsyth D. In utero and
postnatal oral (gavage) exposure of Sprague-Dawley rats to low doses of tributyltin chloride.
Part 1: Toxicology, Histopathology and Clinical Chemistry. Food and Chemical Toxicology Feb;
42(2):211-20, 2004
H. Tryphonas, G. Cooke, D. Caldwell, G. Bondy, M. Parenteau S. Hayward and O. Pulido. Oral
(gavage), in utero and post-natal exposure of Sprague-Dawley rats to low doses of tributyltin
chloride. Part II: Effects on the immune system. Food and Chemical Toxicology Feb;
42(2):221-35.2004.
WJ Bowers, JS. Nakai, I Chu, M Wade, D Moir, S Gill, R Mueller, O Pulido.
Early developmental neurotoxicity of a PCB/organochlorine mixture in rodents after gestational
and lactational exposure. Toxicol Sci.; 77(1):51-62. 2004.
Bowers, W.J., Nakai, J.S., Chu, I., Wade, M., Moir, D., Gill, S., Mueller, R., Pulido, O.
Neurobehavioral toxicity of in utero and lactational exposure to a chemical mixture based on
blood levels in Canadian Arctic populations. Neurotoxicology and Teratology, 25:395, 2003
Gill, S., Murphy, M., Clausen, J., Richard, D., Quilliam, M. MacKinnon, S., LeBlanc, P. & Pulido
O. Neural Injury Biomarkers of Novel Shellfish Toxins, Spirolides. A pilot study using
immunochemical and transcriptional Analysis. Neurotoxicology 34: 593-604, 2003.
R.Mueller, S. Gill and Olga Pulido. The monkey (Macaca fascicularis) heart neural structures
and conducting system. An immunochemical study of selected neural biomarkers and
glutamate receptors. Toxicologic Pathology, 31: 1-8, 2003.
Wang, G. -S.; Karamchandani, J.; Pulido, O.; Rosenberg, L.; Scott, F.W. Altered islet
homeostasis before classic insulinitis in BB rats. Diabetes Metab. 28, 3S90–3S97, 2002.
Bondy, G.; Barker, M.; Cooke, G.; Curran, I.; Doucet, J.; Gill, S.; Lok, E.; Mehta, R.; Pulido, O;
Robertson, P.; Rowsell, P.; Norstrom, R; Moisey, J. In Synopsis of Research Conducted under
the 2001-2002 Northern Contaminants Program, Kalhok, S., Ed.; Indian and Northern Affairs
Canada, Ottawa, 2002.
O. Pulido. Ochratoxin hepatotoxicity. Moderators Report. In Registry of Toxicologic Pathology
for Animals (RTPA). Armed Forces Institute of Pathology (AFIP), Washington, D.C., 2002.
O. Pulido. Fumonisin B1 renal toxicity. Moderators Report. In Registry of Toxicologic Pathology
for Animals (RTPA). Armed Forces Institute of Pathology (AFIP), Washington, D.C, 2002.
O.Pulido. Retinal Degeneration in Rats and Dogs associated to the oral administration of ATP-
sensitive potassium channel activators. Moderators Report. In Registry of Toxicologic
Pathology for Animals (RTPA). Armed Forces Institute of Pathology (AFIP), Washington, D.C,
2002.
O.Pulido. Myopathy related to the administration of HMG-CoA reductase inhibitor. Moderators
Report. In Registry of Toxicologic Pathology for Animals (RTPA). Armed Forces Institute of
Pathology (AFIP), Washington, D.C., 2002.

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Olga Pulido, Don Richard, Michael Quilliam, Joann Clausen, Meghan Murphy, Peter Smyth,
Ruedi Mueller and Santokh Gill. Toxicological Neuropathology from Domoic Acid to Spirolides.
The Health Canada Experience. Can. J. Fisheries and Aquatic Sci. Proc. of the 7th
Canadian
Workshop on Harmful Marine Algae, 2001.
Bryce, F., Iverson, F., Andrews, P., Barker, M., Cherry, W., Mueller, R., Pulido, O., S. Hayward,
S., Fernie, S. and Arnold, D.L. Effects elicited by toxaphene in the cynomolgus (M. fascicularis)
monkey. A pilot study. Food Chemical Toxicology, 39:1243-1251, 2001.
Gill SS, Pulido OM. Glutamate receptors in peripheral tissues: current knowledge, future
research, and implications for toxicology. Toxicol Pathol. 2001 Mar-Apr; 29(2):208-23. Review.
Gill, S., Mueller, R., McGuire, P. and Pulido, O. Potential target sites in peripheral tissues for
excitatory neurotransmission and excitotoxicity. Toxicologic Pathology 28:277-284, 2000.
Pulido, O., Mueller, R., Smyth, P., Clausen, J. and Gill, S. Heart and brain glutamate receptors-
a common mechanism for excitotoxicity? Brain Pathology 10:681, 2000.
Wang, G.-S., Gruber, H., Smyth, P., Pulido, O., Rosenberg, L., Duguid, W. and Scott F.W.
Hydrolysed casein diet protects diabetes-prone BB rats from developing diabetes by promoting
islet neogenesis. Journal of Autoimmunity 15:407-416, 2000.
Sarwar, G; M.R. L'Abbe, S.P.J. Brooks, E. Lok, G. Cooke, O. Pulido and P. Thibert. Dietary
Phytoestrogens: Safety, Nutritional Quality and Health Considerations in ACS book entitled
"Quality Management of Nutraceuticals: edited by C-T. Ho and Q.Y. Zheng., 2000
Gill, S., Pulido, O., Mueller, R. and McGuire, P. Immunohistochemical characterization of
metabotropic glutamate receptors in the rat heart. Brain Research Bulletin 48:143-146, 1999.
Pulido, O. Demonstration of glutamate receptors in body tissues and their relation to food
safety and excitotoxicity. Soc. for Neuroscience Press Book, Part II, pg. 121, 1999.
Gill, S., Pulido, O., Mueller, R. and McGuire, P. Molecular and immunochemical
characterization of ionotropic glutamate receptors in the rat heart. Brain Research Bulletin 46:
429-434, 1998.
J. Truelove, R. Mueller, O.Pulido, L. Martin, S. Fernie, and F. Iverson. 30- Day Oral Toxicity of
Domoic Acid in Cynomolgu Monkeys: Lack of Overt Toxicity at Doses Approaching the Acute
Toxic Dose. Natural Toxins 5: 111-114, 1997
J. Truelove, R. Mueller, O. Pulido and F. Iverson. Subchronic toxicity Study of Domoic Acid in
Rat. Food Chem. Tox. 34: 525, 1996
Niles, L.P., Pulido,O.M. and Pickering, D.S. Age-related changes in GABA and
Benzodiazepine receptor binding in rat brain are influenced by sampling time. Prog.
Neuropsychopharmacol. & Biol. Psychiat. , 12: 337-344, 1988.
Pulido, O.: Aging and a multicultural Society. In "Proc. of Multicultural Health Workshop",
Hamilton, Ontario, 1988, Pulido, O. and Niles, E. (Eds), Pine Crest.
Pulido, O.: Biology of Human Aging. Monograph and Videotapes I-III, General Concepts in
Gerontology and Theories of Aging. E. Brain (Ed). McMaster University, Hamilton, 1988.

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Pulido, O. and Clifford, J.: Age-associated changes in the circadian rhythm of retinal N-acetyl
serotonin (NAS) and melatonin in rats with pigmented eyes. Exp. Gerontology 21:23-30, 1986.
Davis, D., Majumdar, B., Pulido, O.: Report and Recommendation on The Impact of
Transculturalism on Health and Health Care. Proc. Transcultural Health Workshop, Faculty of
Health Sciences, McMaster University, 1987.
Pulido, O.M., Clifford, J., Brown, C. and Cole, S.: Pineal and extra-pineal N-acetyl serotonin
(NAS) and melatonin as function of age. International Workshop on the Pineal Gland during
Development, Neuroendocrinology Lett. Vol. 7(4), 1985.
Niles, L.P. and Pulido, O.M.: Age-related changes in GABA receptors. International Workshop
on the Pineal Gland during Development, Neuroendocrinology Lett. Vol. 7(4), 1985.
Brown, G.M., Pulido, O., Grota, L.J. and Niles, L.P.: N-acetyl-serotonin in the central nervous
system. Prog. Neuropsycho-pharmacol. and Biol. Psychiat. 8:475-480, 1984.
Brown, G.M., Niles, L.P., Pulido, O., Ho, A. and Grota, L.J.: Extrapineal melatonin and N-acetyl
serotonin. PECS Proceedings, 1984.
Pulido, O., Brown, G.M. and Grota, L.J.: B-adrenergic regulation of N-acetyl serotonin (NAS)
synthesis in the rat cerebellum. Life Sciences 33:1081, 1983.
Pulido, O., Brown, G.M. and Grota, L.J.: An Immunohistochemical method for the localization
of N-acetyl serotonin (NAS) in the central nervous system. Description, validation and
application of the technique. J. Histochem. Cytochem. 31:1343, 1983.
Psarakis, S., Pulido, O., Brown, G.M., Grota, L.J. and Smith, G.K.: Identification and
quantitation of N-acetyl serotonin in the developing hippocampus of the rat by
immunohistology. Prog. Neuropsychopharmacol. and Biol. Psychiat. 6:439, 1982.
Pulido, O., Brown, G.M. and Grota, L.J.: Localization of N-acetyl serotonin (NAS) in the rat
hindbrain by immunohistology. Prog. Neuropsychopharmacology 5:573, 1981.
Pulido, O., Brown, G.M. and Grota, L.J.: Immunohistological localization of N-acetyl serotonin
in the rat brain. J. Histochem. and Cytochem. 28:613, 1980.
Pulido, O.M., Bencosme, S.A., de Bold, M.L. and de Bold, A.: Intracellular B-cell serotonin and
the dynamics of insulin release. Diabetologia 15:197-204, 1978
Pulido, O., de Bold, A., de Bold, M. and Bencosme, S.A.: Demonstration of a tryptaminergic
mechanism in the rat B-cell. Experientia 33:268-270, 1977.
Gonzalez, J.E., Pulido, O. and Rojas, G.: Accion del SH 90 000 C (d-norgestrel) sobre la
estructura endometrial humana. In: “II Reunión Latino-americana SH 90 000 C. México, 1970.
Eds. Scharff, H.J.: Ruiz Albrecht F. Saladruck, Berlin, p. 104, 1972.
Potenza, Von, L., Pulido, O. and Rojas, G.: Zur wirkung won d-norgestral auf die struktur des
menschilichem endometriums vergleichende underschug mit dem light und
electronenmikroskop. Medizinische metteilugen Schering 1:20, 1972.

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Lejter, M., Gonzalez, J.E., Pulido, O. and Cardenas, N.: Sindrome de Reye. Arch. Venez.
Pueric y Pedt. 2:31, 1972.
Pulido, O. and Contreras, J.: Embarazo tubarico en pacientes con espiral intrauterino. Bol.
Med. Hosp. Centr. FF. AA. (Caracas) 2:7, 1971.