presented by HAFIZ M WASEEM university of education LAHORE Pakistan i am from mailsi vehari and studied in lahore bsc in science college multan msc from lahore

2. Inflammation and its Mechanism

3. HAFIZ M WASEEM UNIVERSITY OF
EDUCATION LAHORE

4.  Inflammation refers to your body’s process of
fighting against things that harm it, such as
infection, toxins, in an attempt to heal itself
 When something damages your cell your body
releases a response chemicals that trigger a
response from your immune system
 Without inflammation wounds go unchecked never
heal

5.  1793-John Hunter described that
inflammation is not a disease it is salutary
effect on host
 1893-Conheihm used microscope to observe
changes in vessels
 1880-Metchinkoff discovered phagocytosis
Paul Ehrilch proposed humoral theory of
immunity
 1924-Lewis explained role of chemical
mediators in inflammation

7.  Infective agents like bacteria, viruses and their
toxins, fungi parasites
 Immunological agents like cell-mediated and
antigen-antibody reactions
 Physical agents like heat, cold, radiation, mechanical
trauma
 Chemical agents like organic and inorganic poisons
 Inert materials such as foreign bodies

9. Acute inflammation is a short- term process occuring in
response to tissue injury, usually appearing within few
minutes or hours
Cellular Events
Margination
Adhesion
Emigration
Chemotaxis
Phagocytosis
Mediators
Histamines
Serotins
Plasmins
Adrenalins and
Non Adrenalins
Neutrophilic
Proteases

11.  Chronic inflammation is the ability of body to repair and
overcome the damage and it is vary with the cause of
inflammation
 It is Slow, long-term lasting for prolonged periods of several
months to years
Granulomatous Chronic inflammation
Non Granulomatous Chronic
inflammation

12. Goals
To get rid of initial cause of cell injury
To get rid of consequences of injury
To prevent other organ system damage
Initiate the process of repair

14. • https://www.slideshare.net/mobile/Amrit
Jaishi/inflammation-75876889
• https://www.slideshare.net/mobile/BilalD
ear1/acute-inflammationpathology
• https://en.m.wikipedia.org/wiki/Inflamm
ationhttps://pubmed.ncbi.nlm.nih.gov/18
240538
• /https://www.medscape.com/answers/32
5370-155833/