1. IMS Department of Biochemistry Phase I Lecturer : Dr.B.Raghu Nucleic acid chemistry - Tutorial I . Multiple Choice Questions: Choose the correct answer 1. The following compound is present in RNA but absent from DNA: A. Thymine B. Cytosine C. Uracil D. Guanine 2. Complete acid hydrolysis of nucleic acid yields all of the following except: A. Phosphoric acid B. Purines C. 5-carbon sugar D. Adenosine

2. 3. Which is a pyrimidine nucleoside? A. Guanine-5-phosphate B. Adenosine C. Thymidine D. Guanosine 4. A nucleotide contains: A. Base + pentose + phosphate B. Base + pentose C. Base + P04 D. Base + hexose + phosphate

3. 5. In nucleic acids, nucleotides are linked to each other by: A. 3',5' -phosphodiester linkage B. Glycosidic linkage C. Ester linkage D. Salt-type of linkage 6. Nucleic acids contains: A. Phosphoric acids and purine bases B. Purine and pyrimidine bases, amino acids and phosphoric acid C. Ribose or deoxyribose, purine and pyrimidine bases and phosphoric acid D. Amino acids, ribose and phosphoric acid

4. 7. An example of a nucleoside is: A. Cyclic AMP B. AMP C. ATP D. Adenosine 8. If the base sequence of a segment of DNA is pCpApGpTpApGpC, which of the following sequence is complementary? A. pGpTpCpApTpCpG B. pGpCpTpApCpTpC C. pCpGpApTpGpApC D. pTpApGpCpApGpT

5. II. Short Answer Questions: 1.Nucleoside 2.Nucleotide 3.Chargaff’s rule 4.Types of RNA III. Short notes: 1.Structure of DNA 2.Structure of tRNA