This Slideshare states the use of nanotechnology in the pharmaceutical field. How nanotechnology can be useful in the pharma field. Polymer plays an important role in the pharma field.

1. DISCOVER . LEARN . EMPOWER
University Institute of Pharma Sciences
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Master in Pharmaceutics
PRESENTED BY :
Name - MANOJ DALABEHERA
UID – 22MPH10010
TOPIC- NANO TECHNOLOGY IN PHARMACEUTICAL FIELD

2. CONTENTS
• INTRODUCTION
• WHY DO WE NEED IT?
• CLASSIFICATION
• USE OF NANOTECHNOLOGY IN PHARMACETICAL FIELD
• DISSCUSSION
• CONCLUSION
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3. INTRODUCTION
• Nano derives from Greek word “ Nanos” which mean dwraf or extremly small.
• Nano particles are solid colloidal particles ranging from 1 to 1000nm in size ,they consist of macromolecular
materials in which active ingredients ( drug or biologically active material )is ,dissolved ,entrapped or
encapsulated or absorbed .
• Nanotechnology is the act of purposefully manipulating matter at the atomic scale, otherwise known as the
“nanoscale”.
• In pharmacy its all about synthesizinig, characterizing and screening the particle at nano level.
• Nanotechnology is the part of “Novel Drug Delivery System’’.
• Novel Drug Delivery System is an advanced drug delivery system to improve therapeutic effect and control
the release of drug .
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4. 4
WHY DO WE NEED IT ?
 Nanotechnology in pharmaceutical helps in the formulation of more advanced drug delivery
system and so it is an important and powerful tool as an alternative to conventional dosage form .
 Pharmaceutical nanotechnology is a specialized field which will change the fate of the
Pharmaceutical industry in near future .
 Pharmaceutical nanotechnology helps to fight against several diseases and also by detecting the
microorganisms and viruses causing the disease.
Pharmaceutical nanotechnology has played a very key to overcome several drawback of
conventional dosage form for like tablets, capsule etc.
The conventional forms suffered with drawback like low bioavailability ,poor patient
compliance ,damage to healthy cells etc. which were rectified using pharmaceutical
nanotechnology.

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CLASSIFICATION

6. USE OF NANOTECHNOLOGY ON PHARMACEUTICAL FIELD
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 Pharmaceutical nanotechnology is the exciting ,rapidly emerging branch of medical science
that deals with harnessing nanoscale materials as drug delivery and /or diagnostic tool.
 As drug delivery tool ,nano delivery system can be used to enhance the site-specific ,targeted
delivery precise medicine .
 This typically results in signicfiant reduction in side effects and concomitant improvments in
efficacy.
 For example,Doxorubicin is an older common chemotherapeutic agent with notable
cardiotoxicity .
 In the past ,its adverse effects on the heart have curtailed its usefulness .But a new liposomal
delivery form , in which doxorubicin is encapsulated in lipid nanopartical ,is vastely less
cardiotoxic .
 Thus nanotechnology has conferred promisining new life to this toxic old drug .

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8. ADVANTAGE
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 Enhancement of Solubility and Bioavailability.
 Protection from Toxicity.
 Sustained delivery.
 Protection from Chemical (PH), Physical & Biological (ENZYMES), Degradation.
 Decrease Side effect of Coventional Drugs.
 Improve therapeutic effect.
DISADVANTAGE
 High Cost
 Difficulties in scale of Processes
 Easy Inhability of Nano particles resulting into Lung Disease.
 High ability to aggregate in biological system.
 High Immunogenecity.

9. DISCUSSION
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 Some of the challenges and opportunities in nanomedicine involve improving the
specificity of these nanostructures to more precisely target specific areas of the body.
 Another goal is to reduce immunogenicity.
 The longer the immune system permits nanoparticles to circulate, the more likely they are
to reach their intended targets.
 Strategies to accomplish this include altering their coating or chemical functionalization
using a number of substances, including polymers, natural polysaccharides, antibodies, cell
membranes (for example, erythrocyte membranes), “turnable” surfactants and peptides.
 More than one thousand patents have been issued to date and scores of products have
advanced to the clinical trial stage.
 A large handful of products, including the nano-encapsulated doxorubicin referenced
above, already are in use.
 Essentially, future challenges include improvements in drug loading and release, and
further development of the potential of metallic nanoparticles to enhance both diagnosis and
treatment.

10. CONCLUSION
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 This new Drug delivery system allows the desire drug to accumulate into
the inflamed tissue in the higher efficacy.
 The drug is concentrated at its site of action, which reduces possible
adverse effect and enhances the effect of the adminstered dose.
 The sustained drug release allows pharmacological effect to be extended
due to the prolonged presence time of the carrior system at the targeted
inflamed area.

11. THANK YOU
For queries
Email: 22MPH10041@cuchd.in
22MPH10010@cuchd.in
22MPH10002@cuchd.in
22MPH10018@cuchd.in