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Lower GI-Bleed
Definition
• Lower GI - bleeding is defined as abnormal hemorrhage into
the lumen of the bowel from a source distal to the ligament
of Treitz.
• Normal faecal blood loss - 1.2 ml/day
• Significant - > 10ml/day
Anatomy
 The lower gastrointestinal tract comprises of:
(a) Bowel or intestine
 Small intestine, which has three parts:
 Duodenum - Starts from Ligament of Trietz
 Jejunum
 Ileum
 Large intestine, which has three parts:
 Cecum (the vermiform appendix is attached to the
cecum).
 Colon (ascending colon, transverse colon, descending
colon and sigmoid flexure)
 Rectum
(b) Anus
Ligament of TREITZ (Suspensory ligament/muscle
of duodenum )
A fibromuscular band that suspends duodenojejunal flexure from right crus of
diaphragm (a surgical landmark of duodenojejunal flexure)
Small intestine blood supply and innervation
Lymphatic drainage of small intestine
The small intestine is anchored to the abdominal by the
mesentery, a key structure involved in its lymphatics. The
mesentery contains an extensive lymphatic network of
approximately 150 lymph nodes which are arranged into
three stations:
the juxta-intestinal nodes (found along peripheral arterial
arcades)
the intermediate mesenteric nodes (along the jejunal and
ileal arteries), and
(central) superior mesenteric nodes (along the length of
the superior mesenteric artery).
Lymph from the lacteal passes sequentially through these
group of lymph nodes before finally ending up in the
superior mesenteric lymph nodes. Lymph from the
proximal duodenum flows through superior
pancreaticoduodenal, pyloric, hepatic lymph nodes which
drains to the celiac lymph nodes
Blood supply of Large intestine
 Foregut; celiac
trunk
 Midgut; Superior
mesenteric artery
 Hindgut; Inferior
mesenteric artey
 Superior and
Inferior mesenteric
arteries are
connected by
marginal artery of
Drummond
Venous drainage
Drains into
1.Inferior mesenteric vein which joins with splenic vein then
2.Superior mesenteric vein to form Portal vein to flow into
liver
Lymphatic drainage of large intenstine
• Mesenteries are double layers of peritoneum in the abdominal cavity.
• They are the continuations of the visceral and parietal peritoneum with the serous
membranes adhered back to back so that the outer mesothelium secretes serous fluid
into the peritoneal cavity.
Mesentry
STATISTICS BY COLONOSCOPE
Presentation
Lower GI Bleeding typically presents with :
1. Hematochezia (which can range from bright-red blood to old
clots)
2. Melena (If the bleeding is slower or from a more proximal
source)
• Presents as a large volume of bright red
blood PR
• Bleeding > 1.5 I / day
• Hemodynamic instability & shock
• in hematocrit level of 6 g / dL
• Common causes - D / A
• Transfusion of at least 2 units of packed
red blood cells
• Bleeding that continues for 3 days
Massive Bleeding
• Presents as haematochezia
or malena
• Hemodynamically stable
• Causes - Ano-rectal /
Cong./Infla.& Neoplastic
diseases
• Initial in hematocrit level
of 8 g / dL or less
Moderate Bleeding
Occult Blood
 Detected by routine chemical
tests of the stool, with or
without systematic evidence of
chronic blood loss.
 10 ml. of blood loss / day is
necessary to have stool
occult blood positive.
Classification
Site of
Bleeding
Pain + / -
Types
Aetiology
Aetiology
Aetiology - General causes
1. Congenital -
Polyp's / Meckel's diverticulum / HHT
2. Infammotary -
Ulcerative colitis / Infective / Amoebic / Crohn's disease
3. Neoplastic -
Adenomas / Carcinomas / Polyps
4. Vascular-
Angiodysplasia / Ischaemic colitis / Vasculitis / Hamangioma
5. Clotting disorders -
Haemophillia / Leukaemia / Warfarin therapy /DIC
6. Mischellaneous -
Piles / Anal fissure / Injury to rectum
Site-Local causes
1. Small Intestine -
Polyp's / Meckel's diverticulum /Ulcers / Tumours
/Intussusception
2. Large Instestine -
Angiodysplasia / Carcinomas / Colitis /
Diverticulitis
3. Perianal -
Injury / Rupture(Haematoma/Anorectal abscess)
/Carcinoma/Condyloma
4. Anal -
Piles / Anal fissure / Carcinoma / Fistula-in-ano
Painful
 Fissure in Ano
 Fistula in Ano
 Ca. Anal Canal
 Rup. perianal haematoma
 Rup. Ano Rectal abscess
 Endometriosis
 Injury
Painless
1. Blood Alone
a. Polyp
b. Villous Adenoma
c. Diverticular diseases
2. Blood After Defecation
a. Hemorrhoids
3. Blood with mucus
a. Ulcerative colitis
b. Intussusception
c. Ishaemic Colon
4. Blood Streaked on stool
a. Ca. Rectum
Clinical Presentations
Bleeding Per rectum -
• Bright red blood - Piles / Polyps / Fissure
• Altered blood - Ca / Ulcer / IBD / Dysentery
• Maroon colour - Meckel's diverticulum
• Streaks of blood- Anal fissure
• Splash in pan - Piles
• Red currant jelly- Intussusception
• Blood with mucus - Colitis / Ca / Dysentery
If your bleeding starts abruptly and
progresses rapidly, you could go into
shock. Signs and symptoms of shock
include:
 Vomiting blood, which might be
dark brown and resemble coffee
grounds in texture
 Lightheadedness
 Difficulty breathing
 Fainting
 Chest pain
 Abdominal pain
 Anemia
 Drop in blood pressure
 Not urinating or urinating
infrequently, in small amounts
 Rapid pulse
 Unconsciousness
Patient Assessment
1. AIRWAY
Drowsy patient -vomiting/ hematemesis is present ,then there is
increased risk of aspiration so,patient should be electively intubated
2. BREATHING
Provide supplemental oxygen
To keep SPO2 >95%
3. CIRCULATION
Intravenous access - bilateral with 2 large bore cannulae (16-gauge
minimum)
Rapid IV crystalloid infusion
Vitals
• Blood pressure, heart rate, Any postural hypotension
(Tachycardia is an early sign of shock)
• Narrowing pulse pressure (ind systolic hypotension)
• Patient’s conscious level – confused (shock)
• Compare current vitals with vitals in ED –
is there a worsening trend?
-Urine output:
General
inspection
• Pallor
• Confusion
Peripheries
• Signs of dehydration-CRT
• Any skin manifestation of IBD
Abdomen
• Any tenderness , epigastric mass
• Distension (++ blood in stomach)
Digital rectal
examination
• Any anal fissures or prolapsed hemorrhoids seen
• Hematoschezia,
• Rectal mass
Then proceed with proctoscope to look for any source of bleeding,active bleeding,mass

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CME LGIB.pptx

  • 2. Definition • Lower GI - bleeding is defined as abnormal hemorrhage into the lumen of the bowel from a source distal to the ligament of Treitz. • Normal faecal blood loss - 1.2 ml/day • Significant - > 10ml/day
  • 3. Anatomy  The lower gastrointestinal tract comprises of: (a) Bowel or intestine  Small intestine, which has three parts:  Duodenum - Starts from Ligament of Trietz  Jejunum  Ileum  Large intestine, which has three parts:  Cecum (the vermiform appendix is attached to the cecum).  Colon (ascending colon, transverse colon, descending colon and sigmoid flexure)  Rectum (b) Anus
  • 4. Ligament of TREITZ (Suspensory ligament/muscle of duodenum ) A fibromuscular band that suspends duodenojejunal flexure from right crus of diaphragm (a surgical landmark of duodenojejunal flexure)
  • 5. Small intestine blood supply and innervation
  • 6. Lymphatic drainage of small intestine The small intestine is anchored to the abdominal by the mesentery, a key structure involved in its lymphatics. The mesentery contains an extensive lymphatic network of approximately 150 lymph nodes which are arranged into three stations: the juxta-intestinal nodes (found along peripheral arterial arcades) the intermediate mesenteric nodes (along the jejunal and ileal arteries), and (central) superior mesenteric nodes (along the length of the superior mesenteric artery). Lymph from the lacteal passes sequentially through these group of lymph nodes before finally ending up in the superior mesenteric lymph nodes. Lymph from the proximal duodenum flows through superior pancreaticoduodenal, pyloric, hepatic lymph nodes which drains to the celiac lymph nodes
  • 7. Blood supply of Large intestine  Foregut; celiac trunk  Midgut; Superior mesenteric artery  Hindgut; Inferior mesenteric artey  Superior and Inferior mesenteric arteries are connected by marginal artery of Drummond
  • 8.
  • 9. Venous drainage Drains into 1.Inferior mesenteric vein which joins with splenic vein then 2.Superior mesenteric vein to form Portal vein to flow into liver
  • 10. Lymphatic drainage of large intenstine
  • 11.
  • 12. • Mesenteries are double layers of peritoneum in the abdominal cavity. • They are the continuations of the visceral and parietal peritoneum with the serous membranes adhered back to back so that the outer mesothelium secretes serous fluid into the peritoneal cavity. Mesentry
  • 13.
  • 14.
  • 16. Presentation Lower GI Bleeding typically presents with : 1. Hematochezia (which can range from bright-red blood to old clots) 2. Melena (If the bleeding is slower or from a more proximal source)
  • 17.
  • 18. • Presents as a large volume of bright red blood PR • Bleeding > 1.5 I / day • Hemodynamic instability & shock • in hematocrit level of 6 g / dL • Common causes - D / A • Transfusion of at least 2 units of packed red blood cells • Bleeding that continues for 3 days Massive Bleeding
  • 19. • Presents as haematochezia or malena • Hemodynamically stable • Causes - Ano-rectal / Cong./Infla.& Neoplastic diseases • Initial in hematocrit level of 8 g / dL or less Moderate Bleeding
  • 20. Occult Blood  Detected by routine chemical tests of the stool, with or without systematic evidence of chronic blood loss.  10 ml. of blood loss / day is necessary to have stool occult blood positive.
  • 21. Classification Site of Bleeding Pain + / - Types Aetiology Aetiology
  • 22. Aetiology - General causes 1. Congenital - Polyp's / Meckel's diverticulum / HHT 2. Infammotary - Ulcerative colitis / Infective / Amoebic / Crohn's disease 3. Neoplastic - Adenomas / Carcinomas / Polyps 4. Vascular- Angiodysplasia / Ischaemic colitis / Vasculitis / Hamangioma 5. Clotting disorders - Haemophillia / Leukaemia / Warfarin therapy /DIC 6. Mischellaneous - Piles / Anal fissure / Injury to rectum
  • 23. Site-Local causes 1. Small Intestine - Polyp's / Meckel's diverticulum /Ulcers / Tumours /Intussusception 2. Large Instestine - Angiodysplasia / Carcinomas / Colitis / Diverticulitis 3. Perianal - Injury / Rupture(Haematoma/Anorectal abscess) /Carcinoma/Condyloma 4. Anal - Piles / Anal fissure / Carcinoma / Fistula-in-ano
  • 24.
  • 25. Painful  Fissure in Ano  Fistula in Ano  Ca. Anal Canal  Rup. perianal haematoma  Rup. Ano Rectal abscess  Endometriosis  Injury
  • 26. Painless 1. Blood Alone a. Polyp b. Villous Adenoma c. Diverticular diseases 2. Blood After Defecation a. Hemorrhoids 3. Blood with mucus a. Ulcerative colitis b. Intussusception c. Ishaemic Colon 4. Blood Streaked on stool a. Ca. Rectum
  • 27. Clinical Presentations Bleeding Per rectum - • Bright red blood - Piles / Polyps / Fissure • Altered blood - Ca / Ulcer / IBD / Dysentery • Maroon colour - Meckel's diverticulum • Streaks of blood- Anal fissure • Splash in pan - Piles • Red currant jelly- Intussusception • Blood with mucus - Colitis / Ca / Dysentery
  • 28. If your bleeding starts abruptly and progresses rapidly, you could go into shock. Signs and symptoms of shock include:  Vomiting blood, which might be dark brown and resemble coffee grounds in texture  Lightheadedness  Difficulty breathing  Fainting  Chest pain  Abdominal pain  Anemia  Drop in blood pressure  Not urinating or urinating infrequently, in small amounts  Rapid pulse  Unconsciousness
  • 29. Patient Assessment 1. AIRWAY Drowsy patient -vomiting/ hematemesis is present ,then there is increased risk of aspiration so,patient should be electively intubated 2. BREATHING Provide supplemental oxygen To keep SPO2 >95% 3. CIRCULATION Intravenous access - bilateral with 2 large bore cannulae (16-gauge minimum) Rapid IV crystalloid infusion
  • 30. Vitals • Blood pressure, heart rate, Any postural hypotension (Tachycardia is an early sign of shock) • Narrowing pulse pressure (ind systolic hypotension) • Patient’s conscious level – confused (shock) • Compare current vitals with vitals in ED – is there a worsening trend? -Urine output: General inspection • Pallor • Confusion Peripheries • Signs of dehydration-CRT • Any skin manifestation of IBD Abdomen • Any tenderness , epigastric mass • Distension (++ blood in stomach)
  • 31. Digital rectal examination • Any anal fissures or prolapsed hemorrhoids seen • Hematoschezia, • Rectal mass Then proceed with proctoscope to look for any source of bleeding,active bleeding,mass