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Telomeres Theory of Ageing
& Healthy Life Style
DR. SHARDA JAIN
• Great Teacher & surgeon ,taught for 2 decades in medical college (PGI Chandigarh , LHMC, Delhi )
• ETHICAL COMMITTEE MEMBER OF MEDICAL COUNCIL OF INDIA
• “TEACHER OF THE TEACHER AWARD” by Delhi Gynaecologist forum 2018
• Life time achievement Award from FOGSI (national organisation of Gynaecologists )
*IMA medical Association
*Lady Harding Medical Collage
*Delhi gynaecologist forum
• *ISAR ( Delhi)
• Founder chairman (for a decade )PushpanjaliCrosslayHospital now Max vaishali
• Founder & director of Lifecare Centre & IVF which is serving east Delhi for last 27 year for GYNAE
care , IVF ,Bariatric surgery , Advanced Lap / Hyst Surgery
• FOUNDER & SECRETARY GENERAL OF DELHI GYNAECOLOGIST FORUM ( 2000 )
• Recognised as Great Medical social worker is behind National movements of Female foeticide ,
Anamia Free India , Adolescent Health , Save uterus, Save girl child etc
NOW HER PASSION 360 * CARE ,DOCTORS TRAINING & SAFETY OF DOCTORS
DR. SHARDA JAIN
M.D. (PGIMER), MNAMS,FICOG,FIMSA,
DHM, QM &AHO
PGDMLS (SYMBIOSIS)
“Your body is very precious.
It is our vehicle for
awakening
TREAT IT WITH CARE”
BUDHA
Every One Wants To Know -An Indian YOGI,s
SECRET TO IMMORTALITY
• INDIA HAS MANY STORIES OF BABA & YOGI
WHO LIVED EXEPTIONALLY LONG ..
• TRAILANGA SWAMI OF VARANASI ..300 YRS
• DEVRAHA BABA ..250 YRS
• AUTOBIOGRAPHY OF A YOGI ..MENTIONED
DEATHLESS BABA
• AS A CHILD I WONDERED WHAT WAS THE
SECRET OF THEIR IMMORTALITY ???
E
A
S
T
PREDICTION
2050
American Academy of Anti - Ageing
The world will have more people who live
to see their 100 years than ever before
Anti – Ageing SPA
Movement
of
W
E
S
T
MANY THEORIES ,BUT LEADING CAUSES OF
AGING are few
* OXIDATIVE STRESS
* GLYCATION
* TELOMERE SHORTENING
* CHRONOLOGICAL AGE
ALL WORK TOGETHER TO CAUSE PREMATURE AGING .
******
TODAY EVERYBODY IS AGING PREMATURELY .
A WOMEN OF 30 IS FOUND TO BE 46 Or 50 yrs
TELOMERES THEORY
Is most
ATTRACTIVE !
***
Telomeres –do cell replication &
protection of Chromosomes.
What do Telomeres do?
Telomeres are pink protective pieces
of DNA material at the ends of
chromosomes.
Like the PLASTIC TIPS ON SHOELACES,
telomeres prevent chromosome ends from
fraying and sticking to each other, which would
damage genetic information to cause CANCER,
other diseases ,or PREMATURE AGEING.
WHAT DO TELOMERES DO?
Every time a cell divides, the telomeres get shorter.
After they get too short, the cell no longer can
divide and becomes inactive or dies.
This process is related with aging and age related
diseases.
Evidence clearly shows that people with long
telomeres age healthier & live longer
TELOMERES AND AGING
• It has been proposed that telomere
shortening may be a molecular clock
mechanism that counts the number of times a
cell has divided and when telomeres are too
short, cellular senescence (growth arrest)
occurs.
• It is believed that shortened telomeres in
mitotic (dividing) cells may be responsible for
some of the changes we associate with normal
& premature aging.
Diseases Affected - By
TELOMERE SHORTENING
• CARDIOVASCULAR CANCER
• COPD
• Degenerative Disc Disease
Alzheimer’s
• Osteoarthritis Rheumatoid
Arthritis Osteoporosis General
Immunity Skin Aging
• Macular Degeneration
• Liver Cirrhosis
• Muscular Dystrophy
• Cell & Tissue Transplants
• AIDS
• Progeria
• Dyskeratosis Congenita Idiopathic
Pulmonary Fibrosis
• Cri du Chat syndrome Down’s
Syndrome Fanconi’s Anemia
Tuberous Sclerosis
• Werner’s Syndrome And,
• Aging Itself???????
Can we slowdown the loss of
Telomeres ?
Factors that accelerate
TELOMERE shortening
Homocysteine
Inflammation
Oxidative Stress
Depression
Emotional Stress
Physical TRAUMA
The abnormal stress of modern life has been shown
to greatly hasten the reduction of those telomeres.
The scientist who won the Nobel prize for her
research on telomeres. Elizabeth black burn , states
that lengthening these telomeres will keep people
healthier for longer time ,saving individual from
some disease of Ageing too
Biggest Discovery of Telomerase which rebuild
Telomeres ..is Path Breaking
Telomerase is the enzyme responsible for
RE-BUILDING TELOMERES.
Telomerase activity is observed in fetal tissue, adult
germ cells, and tumor cells.
Telomerase is “turned off” in all other cells.
Can You REVERSE the Signs of
AGING by Artificially Lengthening
the Telomere?
A Real Ground Breaking Study...
Harvard Medical School Professor,
Ronald DePinho,
used the TERT-ER mouse to demonstrate the profound
effect of telomerase activation on age management.
Reverse ageing in brain
Reversed aging in testes
Reversed aging of other Organs
Jaskelioff M, Muller FL, Paik JH, Thomas E, et al. Telomerase reactivation reverses tissue
degeneration in aged telomerase-deficient mice. Nature. 2010 Nov 28
Activation of Telomerase
Has Been Shown To:
1 . Immortalize cells
2. Reverse the age of tissue
3. Reverse aging in whole organisms
Telomeres & Telomerase
Activator
The only way to lengthen telomeres in
MODERN MEDICINE is through the activation of
an enzyme called Telomerase. Currently the only
way to activate telomerase is to take
TA-65
TELOMERASE ACTIVATOR
Is it a key to unlocking
the longevity puzzle?
GREAT
NEWS
A HEALTHY LIFESTYLE
MAY LENGTHEN
TELOMERES, REVERSING
CELLULAR AGING !
• RESEARCHERS FOUND EVIDENCE THAT
HEALTHY LIFESTYLE MAY RESULT IN
LONG TELOMERES .
• THE INTENTION OF STUDIES WAS TO
EXPLORE THE RELATIONSHIP BETWEEN
COMPREHENSIVE LIFESTYLE CHANGES
AND TELOMERE LENGTH .
Enough Studies which show that
we can Keep
Telomeres Long ?
▪ Right Exercise
▪ Anti-Oxidants
▪ Omega 3’fatty
acids
▪ Vitamin D3
▪ Don’t Smoke
▪ Weight
Management
▪ Reduce Stress
▪ Reduce Depression
▪ Reduce Pessimism
▪ Be Happy!
CARE TODAY
TOMORROW MAY BE TOO LATE !
For HEALTHY AGEING
Dr SUDHIR jAIN
Sow at
a young age
to reap at
a ripe age
Young Dr Sharda
Old Dr. Sharda
LIVING FOREVER OR FOR 100 YRS
MAY NOT BE POSSIBLE!!
BUT FEELING & LOOKING MUCH
YOUNGER THAN ONE,s BIOLOGICAL AGE IS
SOMETHING MOST PEOPLE CAN LIVE WITH !
Scientific studies in recent years support
what yogies have been claiming for
centuries : MEDITION ,YOGA , & LIVING A
SPRITUAL LIFE ACTUALLY REDUCES the
clinical bench marks of BIOLOGICAL AGE
or the age of one,s body & mind appear
to be.
MEDITATION & TELOMERES
INDIA IS WORLD GURU ON MEDITATION
“INDIAN RISHIS”
have shown that
Natural ageing
process can be
reversed through
meditation .
Meditation actually
change our very DNA
.
Modern Studies also show that
meditation INCREASES OR HELPS IN
MAINTAINING THE VOLUME OF GREY
MATTER IN THE BRAIN , which normally
decrease with age. Meditation helps one
feel, Look & behave much younger than
one’s physical age
even on a cellular level
Studies of people who meditate regularly
have shown that the
LENGTH OF THEIR TELOMERES
ACTUALLY INCREASE OVER TIME ,
REVERSING THE NATURAL AGEING
PROCESS
& giving them some protection
from many modern civilisation diseases.
This is the only reason --why yogis easily
overcome the fear of death & once the fear
of death is gone, they develop a child like
attitude in old age- even appeasing
YOUNG PERSONALITY & LOOKS.
TAKE HOME MESSAGE
India is world GURU of meditation
Why does not everyone in INDIA meditate
then? People claim they are too busy ,or it’s too
difficult or it’s not their thing .
But feeling younger, be
healthier-- everyone desires!
Surely you can do 15 – 30 minutes a day or more
to practice MEDITATION OR SILENCE
something that will give lasting benefits
THE MYSTERY OF IMMORTALITY—
so very Easy !!
WHO WOULD HAVE THOUGHT THAT THE
*SECRET OF HUMAN,s LONGEVITY
* SECRET OF INDIAN YOGI,s
IMMORTALITY
HAS BEEN PROBABLY KNOWN FOR
THOUSANDS OF YEARS IN INDIA, AND
THAT IS
SO VERY EASY…
WAY TO PREVENT/TREAT LIFE STYLE
DISEASES..& be healthy
Vegetarian
diet
Physical
Exercise
Yoga +
Pranayam
Detoxification
Fasting &
Ayurveda
Purification
of Mind
Meditation DE-
ADDICTION
De-stress
Your self
Confidence
Building
Workshop
Recreational
Exercises
Grace Full Anti Ageing
Autologous
Stem Cell
therapy
360* DEGREE CARE
Detoxification
Antioxidants
HRT
Exercise
Dance
Yoga
Aerobics
Zumba
Walk
GROUP ACTIVITY
Is Best
D*iet
MEDITATION
PRANAYAM
Consultation
Anti- Aging
Physician
*LAB TESTS
*Genomic Tests
*Food Allergy
Test
*Advance Metabolic
Analysis
RE GENERATIVE STEM CELL THERAPY
Cosmetic /
Aesthetic
Issues
O2 Cell RT
4 gurus who practice 360 * care feel
there is merit in assumption that
spiritual living has magical
effect in aging
VENUE : 11 GAGAN VIHAR , NEAR KARKARI
A unit of Llife care Centre
Cure morbid obesity / Diabetes/ fatty Liver /
Metabolic & Function Well being / cell
therapies / Diet Correction /
Nutraceuticals / Aesthetics
Monday to Saturday
Contact No : 965058833 ,01122414049
SMART METABOLIC
ANTI – AGEING CENTRE

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Telomeres Theory of Ageing & Healthy Life Style

  • 1. Telomeres Theory of Ageing & Healthy Life Style DR. SHARDA JAIN
  • 2. • Great Teacher & surgeon ,taught for 2 decades in medical college (PGI Chandigarh , LHMC, Delhi ) • ETHICAL COMMITTEE MEMBER OF MEDICAL COUNCIL OF INDIA • “TEACHER OF THE TEACHER AWARD” by Delhi Gynaecologist forum 2018 • Life time achievement Award from FOGSI (national organisation of Gynaecologists ) *IMA medical Association *Lady Harding Medical Collage *Delhi gynaecologist forum • *ISAR ( Delhi) • Founder chairman (for a decade )PushpanjaliCrosslayHospital now Max vaishali • Founder & director of Lifecare Centre & IVF which is serving east Delhi for last 27 year for GYNAE care , IVF ,Bariatric surgery , Advanced Lap / Hyst Surgery • FOUNDER & SECRETARY GENERAL OF DELHI GYNAECOLOGIST FORUM ( 2000 ) • Recognised as Great Medical social worker is behind National movements of Female foeticide , Anamia Free India , Adolescent Health , Save uterus, Save girl child etc NOW HER PASSION 360 * CARE ,DOCTORS TRAINING & SAFETY OF DOCTORS DR. SHARDA JAIN M.D. (PGIMER), MNAMS,FICOG,FIMSA, DHM, QM &AHO PGDMLS (SYMBIOSIS)
  • 3.
  • 4. “Your body is very precious. It is our vehicle for awakening TREAT IT WITH CARE” BUDHA
  • 5. Every One Wants To Know -An Indian YOGI,s SECRET TO IMMORTALITY • INDIA HAS MANY STORIES OF BABA & YOGI WHO LIVED EXEPTIONALLY LONG .. • TRAILANGA SWAMI OF VARANASI ..300 YRS • DEVRAHA BABA ..250 YRS • AUTOBIOGRAPHY OF A YOGI ..MENTIONED DEATHLESS BABA • AS A CHILD I WONDERED WHAT WAS THE SECRET OF THEIR IMMORTALITY ??? E A S T
  • 6. PREDICTION 2050 American Academy of Anti - Ageing The world will have more people who live to see their 100 years than ever before Anti – Ageing SPA Movement of W E S T
  • 7. MANY THEORIES ,BUT LEADING CAUSES OF AGING are few * OXIDATIVE STRESS * GLYCATION * TELOMERE SHORTENING * CHRONOLOGICAL AGE ALL WORK TOGETHER TO CAUSE PREMATURE AGING . ****** TODAY EVERYBODY IS AGING PREMATURELY . A WOMEN OF 30 IS FOUND TO BE 46 Or 50 yrs
  • 8. TELOMERES THEORY Is most ATTRACTIVE ! *** Telomeres –do cell replication & protection of Chromosomes.
  • 9. What do Telomeres do? Telomeres are pink protective pieces of DNA material at the ends of chromosomes. Like the PLASTIC TIPS ON SHOELACES, telomeres prevent chromosome ends from fraying and sticking to each other, which would damage genetic information to cause CANCER, other diseases ,or PREMATURE AGEING.
  • 10. WHAT DO TELOMERES DO? Every time a cell divides, the telomeres get shorter. After they get too short, the cell no longer can divide and becomes inactive or dies. This process is related with aging and age related diseases. Evidence clearly shows that people with long telomeres age healthier & live longer
  • 11. TELOMERES AND AGING • It has been proposed that telomere shortening may be a molecular clock mechanism that counts the number of times a cell has divided and when telomeres are too short, cellular senescence (growth arrest) occurs. • It is believed that shortened telomeres in mitotic (dividing) cells may be responsible for some of the changes we associate with normal & premature aging.
  • 12. Diseases Affected - By TELOMERE SHORTENING • CARDIOVASCULAR CANCER • COPD • Degenerative Disc Disease Alzheimer’s • Osteoarthritis Rheumatoid Arthritis Osteoporosis General Immunity Skin Aging • Macular Degeneration • Liver Cirrhosis • Muscular Dystrophy • Cell & Tissue Transplants • AIDS • Progeria • Dyskeratosis Congenita Idiopathic Pulmonary Fibrosis • Cri du Chat syndrome Down’s Syndrome Fanconi’s Anemia Tuberous Sclerosis • Werner’s Syndrome And, • Aging Itself???????
  • 13. Can we slowdown the loss of Telomeres ?
  • 14. Factors that accelerate TELOMERE shortening Homocysteine Inflammation Oxidative Stress Depression Emotional Stress Physical TRAUMA
  • 15. The abnormal stress of modern life has been shown to greatly hasten the reduction of those telomeres. The scientist who won the Nobel prize for her research on telomeres. Elizabeth black burn , states that lengthening these telomeres will keep people healthier for longer time ,saving individual from some disease of Ageing too
  • 16. Biggest Discovery of Telomerase which rebuild Telomeres ..is Path Breaking Telomerase is the enzyme responsible for RE-BUILDING TELOMERES. Telomerase activity is observed in fetal tissue, adult germ cells, and tumor cells. Telomerase is “turned off” in all other cells.
  • 17. Can You REVERSE the Signs of AGING by Artificially Lengthening the Telomere?
  • 18. A Real Ground Breaking Study... Harvard Medical School Professor, Ronald DePinho, used the TERT-ER mouse to demonstrate the profound effect of telomerase activation on age management. Reverse ageing in brain Reversed aging in testes Reversed aging of other Organs Jaskelioff M, Muller FL, Paik JH, Thomas E, et al. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 2010 Nov 28
  • 19. Activation of Telomerase Has Been Shown To: 1 . Immortalize cells 2. Reverse the age of tissue 3. Reverse aging in whole organisms
  • 20. Telomeres & Telomerase Activator The only way to lengthen telomeres in MODERN MEDICINE is through the activation of an enzyme called Telomerase. Currently the only way to activate telomerase is to take TA-65 TELOMERASE ACTIVATOR Is it a key to unlocking the longevity puzzle?
  • 21. GREAT NEWS A HEALTHY LIFESTYLE MAY LENGTHEN TELOMERES, REVERSING CELLULAR AGING !
  • 22. • RESEARCHERS FOUND EVIDENCE THAT HEALTHY LIFESTYLE MAY RESULT IN LONG TELOMERES . • THE INTENTION OF STUDIES WAS TO EXPLORE THE RELATIONSHIP BETWEEN COMPREHENSIVE LIFESTYLE CHANGES AND TELOMERE LENGTH .
  • 23. Enough Studies which show that we can Keep Telomeres Long ? ▪ Right Exercise ▪ Anti-Oxidants ▪ Omega 3’fatty acids ▪ Vitamin D3 ▪ Don’t Smoke ▪ Weight Management ▪ Reduce Stress ▪ Reduce Depression ▪ Reduce Pessimism ▪ Be Happy!
  • 24. CARE TODAY TOMORROW MAY BE TOO LATE ! For HEALTHY AGEING Dr SUDHIR jAIN
  • 25. Sow at a young age to reap at a ripe age Young Dr Sharda Old Dr. Sharda
  • 26. LIVING FOREVER OR FOR 100 YRS MAY NOT BE POSSIBLE!! BUT FEELING & LOOKING MUCH YOUNGER THAN ONE,s BIOLOGICAL AGE IS SOMETHING MOST PEOPLE CAN LIVE WITH ! Scientific studies in recent years support what yogies have been claiming for centuries : MEDITION ,YOGA , & LIVING A SPRITUAL LIFE ACTUALLY REDUCES the clinical bench marks of BIOLOGICAL AGE or the age of one,s body & mind appear to be.
  • 28. INDIA IS WORLD GURU ON MEDITATION “INDIAN RISHIS” have shown that Natural ageing process can be reversed through meditation . Meditation actually change our very DNA .
  • 29. Modern Studies also show that meditation INCREASES OR HELPS IN MAINTAINING THE VOLUME OF GREY MATTER IN THE BRAIN , which normally decrease with age. Meditation helps one feel, Look & behave much younger than one’s physical age even on a cellular level
  • 30. Studies of people who meditate regularly have shown that the LENGTH OF THEIR TELOMERES ACTUALLY INCREASE OVER TIME , REVERSING THE NATURAL AGEING PROCESS & giving them some protection from many modern civilisation diseases.
  • 31. This is the only reason --why yogis easily overcome the fear of death & once the fear of death is gone, they develop a child like attitude in old age- even appeasing YOUNG PERSONALITY & LOOKS.
  • 32. TAKE HOME MESSAGE India is world GURU of meditation Why does not everyone in INDIA meditate then? People claim they are too busy ,or it’s too difficult or it’s not their thing . But feeling younger, be healthier-- everyone desires! Surely you can do 15 – 30 minutes a day or more to practice MEDITATION OR SILENCE something that will give lasting benefits
  • 33. THE MYSTERY OF IMMORTALITY— so very Easy !! WHO WOULD HAVE THOUGHT THAT THE *SECRET OF HUMAN,s LONGEVITY * SECRET OF INDIAN YOGI,s IMMORTALITY HAS BEEN PROBABLY KNOWN FOR THOUSANDS OF YEARS IN INDIA, AND THAT IS SO VERY EASY…
  • 34. WAY TO PREVENT/TREAT LIFE STYLE DISEASES..& be healthy Vegetarian diet Physical Exercise Yoga + Pranayam Detoxification Fasting & Ayurveda Purification of Mind Meditation DE- ADDICTION De-stress Your self Confidence Building Workshop Recreational Exercises Grace Full Anti Ageing Autologous Stem Cell therapy
  • 35. 360* DEGREE CARE Detoxification Antioxidants HRT Exercise Dance Yoga Aerobics Zumba Walk GROUP ACTIVITY Is Best D*iet MEDITATION PRANAYAM Consultation Anti- Aging Physician *LAB TESTS *Genomic Tests *Food Allergy Test *Advance Metabolic Analysis RE GENERATIVE STEM CELL THERAPY Cosmetic / Aesthetic Issues O2 Cell RT
  • 36. 4 gurus who practice 360 * care feel there is merit in assumption that spiritual living has magical effect in aging
  • 37. VENUE : 11 GAGAN VIHAR , NEAR KARKARI A unit of Llife care Centre Cure morbid obesity / Diabetes/ fatty Liver / Metabolic & Function Well being / cell therapies / Diet Correction / Nutraceuticals / Aesthetics Monday to Saturday Contact No : 965058833 ,01122414049 SMART METABOLIC ANTI – AGEING CENTRE