The area of Genomics uses technologically advanced methods to comprehensively understand how and in which way the flow of genetic information works. Genomics explores the basic cellular processes of growth and development that finally translate the knowledge to build a proper model which will be helpful to identify changes that cause disease and subsequently predict the pathways to diagnose as well as prevent the disease.
Our genomic section is now capable of doing whole genome sequencing, targeted gene sequencing, RNA expression, etc routinely.
4. A Genome is the complete set of
DNA sequences in an organism
and contains all of the
instructions required for that
organism to function, including
embryogenesis, growth,
responding to the environment,
and healing from disease. The
Human Genome - the complete
map of all 23 large DNA
sequences (chromosomes) that
encodes our species - comprises
a total of around 3 billion base
pairs contained within the nuclei
of each of our cells.
5. The study of genomics also
has enormous benefits at a
population level. By
aggregating genomic profiles
from across the population
we can develop invaluable
datasets to which advanced
analytics and AI can be
applied to develop a much
more detailed understanding
of the polygenetic causative
factors, and thus potential
treatments, of disease.
6. This is particularly the case for rare genetic diseases, which require large
datasets to find statistically significant correlations, which can identify
causations. The human genome contains around 25.000 genes, each of which
typically encodes a single protein that performs a specific biological function in
the cell, such as regulating cell metabolism, growth or shape.
7.
8. Understanding our own genomes then, particularly where and what mutations we have
in coding or non-coding regions of DNA, is critical to understanding our personal
molecular biology and our personal health. Sequencing the genomes of other species,
meanwhile is useful in understanding the biology of commercial crops, pathogens
causing infectious diseases and model organisms to understand fundamental concepts
of biology. Sequences from specimens can be compared to help scientists track the
spread of a virus, how it is changing, and how those changes may affect public health.