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Bronchiolitis
Epidemiology, Etiology
Clinical Features, Complications, Management
Prognosis and Prevention
Prof. Imran Iqbal
Fellowship in Pediatric Neurology (Australia)
Prof of Paediatrics (2003-2018)
Prof of Pediatrics Emeritus, CHICH
Prof of Pediatrics, CIMS
Multan, Pakistan
(God speaking to Prophet Muhammad (PBUH)
And, in fact, You have a great moral character
Al Quran surah Qalam 68:5
Case scenario
• A 6 months old baby presents in emergency with
runny nose and cough and for the last 2 days. Baby
is feeding much less than before.
• On examination, baby is having frequent dry cough.
His temperature is 99.5 F. His respiration is 60 per
minute and chest indrawing is present. On
auscultation of chest, diffuse expiratory rhonchi
and fine inspiratory crepitations are bilaterally
audible.
• What is your diagnosis ?
Causes of Wheezing in infancy
• COMMON CAUSES
• Bronchiolitis
• Viral bronchitis
• Asthma
• Pneumonia (viral + bacterial infection)
• RARE CAUSES
• GERD
• Heart failure
• Cystic fibrosis
• Immunodeficiency
• Ciliary dyskinesia
• Congenital lobar emphysema
Bronchiolitis - Epidemiology
• Seen in infants up to 2 years of age
• Occurs in epidemics usually in winter months
• Can be mild or severe
• Resolves in 10 – 14 days
Bronchiolitis - Etiology
• Caused by RSV (Respiratory Syncytial Virus)
• Human metapneumo virus
• Parainfluenza virus
Bronchiolitis - Pathogenesis
• Mucosal edema
• Mucus secretion
• Cell necrosis, cell debris
• Bronchiolar obstruction
• Hyperinflation
• Atelectasis
Bronchiolitis - Clinical Features
• Runny nose
• Cough
• Fever – low grade
• Poor feeding
• Fast breathing
• Chest indrawing
• Prolonged expiration
• Wheezing
• Expiratory rhonchi and inspiratory crackles
Diagnosis
Investigations
• CBC
• CRP
• X-ray Chest
• HRCT chest
• Nasopharyngeal Swab for RSV – antigen test
• NPS for viral / bacterial PCR tests
Chest radiography
Complications
• Pneumonia – viral / bacterial
• Pneumothorax
• Apnea
• Hypoxia
• Respiratory Failure
Assessment of Severity
MANAGEMENT
• SUPPORTIVE MANAGEMENT IS REQUIRED
• IV fluids
• Oxygen
• Clearance of secretions
• NEBULISATION:
• Ipratropium and/or Salbutamol
• Steroids
• Hypertonic saline
• Antibiotics – if superadded bacterial infection
• Hospitalization (not feeding OR lethargy OR hypoxia)
Prevention
Prevention of Bronchiolitis
• Breastfeeding, Nutrition, Micronutrients
• Masks and Social Distancing
• Hand washing,
• Control of smoking, air pollution, cold air
Thank You

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Bronchiolitis 2021

  • 1. Bronchiolitis Epidemiology, Etiology Clinical Features, Complications, Management Prognosis and Prevention Prof. Imran Iqbal Fellowship in Pediatric Neurology (Australia) Prof of Paediatrics (2003-2018) Prof of Pediatrics Emeritus, CHICH Prof of Pediatrics, CIMS Multan, Pakistan
  • 2. (God speaking to Prophet Muhammad (PBUH) And, in fact, You have a great moral character Al Quran surah Qalam 68:5
  • 3. Case scenario • A 6 months old baby presents in emergency with runny nose and cough and for the last 2 days. Baby is feeding much less than before. • On examination, baby is having frequent dry cough. His temperature is 99.5 F. His respiration is 60 per minute and chest indrawing is present. On auscultation of chest, diffuse expiratory rhonchi and fine inspiratory crepitations are bilaterally audible. • What is your diagnosis ?
  • 4. Causes of Wheezing in infancy • COMMON CAUSES • Bronchiolitis • Viral bronchitis • Asthma • Pneumonia (viral + bacterial infection) • RARE CAUSES • GERD • Heart failure • Cystic fibrosis • Immunodeficiency • Ciliary dyskinesia • Congenital lobar emphysema
  • 5. Bronchiolitis - Epidemiology • Seen in infants up to 2 years of age • Occurs in epidemics usually in winter months • Can be mild or severe • Resolves in 10 – 14 days
  • 6. Bronchiolitis - Etiology • Caused by RSV (Respiratory Syncytial Virus) • Human metapneumo virus • Parainfluenza virus
  • 7. Bronchiolitis - Pathogenesis • Mucosal edema • Mucus secretion • Cell necrosis, cell debris • Bronchiolar obstruction • Hyperinflation • Atelectasis
  • 8. Bronchiolitis - Clinical Features • Runny nose • Cough • Fever – low grade • Poor feeding • Fast breathing • Chest indrawing • Prolonged expiration • Wheezing • Expiratory rhonchi and inspiratory crackles
  • 10.
  • 11. Investigations • CBC • CRP • X-ray Chest • HRCT chest • Nasopharyngeal Swab for RSV – antigen test • NPS for viral / bacterial PCR tests
  • 13. Complications • Pneumonia – viral / bacterial • Pneumothorax • Apnea • Hypoxia • Respiratory Failure
  • 15. MANAGEMENT • SUPPORTIVE MANAGEMENT IS REQUIRED • IV fluids • Oxygen • Clearance of secretions • NEBULISATION: • Ipratropium and/or Salbutamol • Steroids • Hypertonic saline • Antibiotics – if superadded bacterial infection • Hospitalization (not feeding OR lethargy OR hypoxia)
  • 17. Prevention of Bronchiolitis • Breastfeeding, Nutrition, Micronutrients • Masks and Social Distancing • Hand washing, • Control of smoking, air pollution, cold air