5. Etiology
• Viral – 40%
• Bacterial -60%
• Viral – RSV, Influenza, parainfluenza, adenovirus
• Bacterial - < 2 months – klebsiella, E coli,
pneumococci, staphylococci
• 3 months to 3 yrs – pneumococci, H influenzae
and staphylococci
• After 3 yrs – pneumococci and staphylococci
6. Etiology
• Chlamydia and mycoplasma – in > 5yrs and
adolescents
• Pneumocystis jiroveci and Histoplasma in
immunocompromised children
• Unknown in one third of cases
7. Risk factors
• Low birth weight
• Malnutrition
• Vitamin A deficiency
• Lack of breast feeding
• Passive smoking
• Family history
• Air pollution
10. Pneumococcal pneumonia
• Transmitted by droplets
• Winter months
• Bacteria multiply in alveoli
• Inflammatory exudate
• Lobar pneumonia
• 1-3 days incubation period
• Fever, chills, cough, rusty sputum
• Tachypnoea, retractions of chest,
• Difficulty in feeding, cyanosis
• Percussion impaired
• Decreased air entry, crepitations and bronchial breathing
11. Pneumococcal pneumonia
• Chest x ray
• CBC – leucocytosis
• Sputum gram staining and
culture
• Blood culture
• Treatment
• Penicillin G
• Augmentin – (amoxycillin
and clavulanate)
• Cefotaxime
• Ceftriaxone
• IV injection – 7 days
12. Staphylococcal pneumonia
• Early infancy and childhood
• Primary infection of alveoli or secondary to
staphylococcal septicaemia
• May be complications of measles, influenza
• May follow pyoderma
• Underlying conditions – cystic fibrosis, DM,
malnutrition
13. Staphylococcal pneumonia
• Initially diffuse lesions
• Lesions suppurate -- brochoalveolar obstruction
• Multiple microabscess – erode brochial wall and
discharge their contents to bronchi
• Pneumatocoeles – pathognomonic finding
• Lung abscess
• Erodes pleura and pericardium
• Empyemia --- < 2yrs is always staphylococcal
18. H influenzae pneumonia
• < 3months to 3 yrs
• Associated bacteremia
• Begins in nasopharynx
and spreads locally or
through blood
• Fever,dyspnoea,retraction
s
• Course is sub acute and
prolonged
• Treatment –
augmentin/cefotaxime/
• ceftriaxone
19. Streptococcal pneumonia
• Group A – may follow
measles, varicella,
influenza or pertusis
• Group B – uncommon
in India – important
cause in west(new
borns)
• Interstitial pneumonia
• haemorrhagic
21. Primary atypical pneumonia
• Mycoplasma
pneumoniae
• Chlamydia
• Legionella
• Common in more than
4 yrs of age
• Winter season
• Droplet infetion
• Subclinical mild
infection
22. Primary atypical pneumonia
• Incubation 12-14 days
• Insidious or abrupt
• Malaise, headache,
fever, sore throat,
myalgia and cough
• Dyspnoea – unusual
• Physical signs are
minimal
23.
24. Primary Atypical pneumonia
• Difficult to differentiate from viral pneumonia
and rickettesial pneumonia
• Diagnosis is by detection of antibodies by
ELISA/PCR
• Treatment – macrolide antibiotics –
erythromycin/azithromycin/clarithromycin
• Or doxycycline
• For 7 – 10 days
25. Viral pneumonia
• Diffuse involvement rather than lobar
• RSV common in infants
• Parainfluenza/influenza/adenovirus
• Interstitial pneumonia
• Clinical signs of consolidation are absent
• X ray – perihilar and peribronchial infiltrates
• Supportive treatment
• Ribavirin for RSV
• Oseltamivir – for influenza
28. COVID 19
• Novel corona virus – detected in wuhan, china in Dec 2019
• Soon spread all over world
• 63 crore people affected so far all over world
• 62 lakh people died officially all over world
• Unofficial ?
• Severe disease less common in healthy children
• Airborne – droplets infection
• Many variants – alpha, beta, gamma, delta, omicron
• Mild cough and cold to Severe acute respiratory syndrome
• RT-PCR/CT Chest/RAT
• Treatment – supportive, oxygen, remdesivir, molnupiravir,
monoclonal antibodies, corticosteroids, IvIg