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Pneumonia in children
Dr Gururaja R
MD,DNB (Paed)
Pneumonia
Pneumonia - classification
• Lobar pneumonia
• Bronchopneumonia
• Interstitial pneumonia
Bronchopneumonia and interstitial
pneumonia
Etiology
• Viral – 40%
• Bacterial -60%
• Viral – RSV, Influenza, parainfluenza, adenovirus
• Bacterial - < 2 months – klebsiella, E coli,
pneumococci, staphylococci
• 3 months to 3 yrs – pneumococci, H influenzae
and staphylococci
• After 3 yrs – pneumococci and staphylococci
Etiology
• Chlamydia and mycoplasma – in > 5yrs and
adolescents
• Pneumocystis jiroveci and Histoplasma in
immunocompromised children
• Unknown in one third of cases
Risk factors
• Low birth weight
• Malnutrition
• Vitamin A deficiency
• Lack of breast feeding
• Passive smoking
• Family history
• Air pollution
Clinical feaures
• Insidious onset
• Starts with URTI
• FEVER
• TACHYPNOEA
• DYSPNOEA
• RETRACTIONS OF CHEST
Chest retractions
Pneumococcal pneumonia
• Transmitted by droplets
• Winter months
• Bacteria multiply in alveoli
• Inflammatory exudate
• Lobar pneumonia
• 1-3 days incubation period
• Fever, chills, cough, rusty sputum
• Tachypnoea, retractions of chest,
• Difficulty in feeding, cyanosis
• Percussion impaired
• Decreased air entry, crepitations and bronchial breathing
Pneumococcal pneumonia
• Chest x ray
• CBC – leucocytosis
• Sputum gram staining and
culture
• Blood culture
• Treatment
• Penicillin G
• Augmentin – (amoxycillin
and clavulanate)
• Cefotaxime
• Ceftriaxone
• IV injection – 7 days
Staphylococcal pneumonia
• Early infancy and childhood
• Primary infection of alveoli or secondary to
staphylococcal septicaemia
• May be complications of measles, influenza
• May follow pyoderma
• Underlying conditions – cystic fibrosis, DM,
malnutrition
Staphylococcal pneumonia
• Initially diffuse lesions
• Lesions suppurate -- brochoalveolar obstruction
• Multiple microabscess – erode brochial wall and
discharge their contents to bronchi
• Pneumatocoeles – pathognomonic finding
• Lung abscess
• Erodes pleura and pericardium
• Empyemia --- < 2yrs is always staphylococcal
Staphylococcal pneumonia
Staphylococcal pneumonia
• Complications
• Disseminated disease
• Bone, joints infection
• Liver abscess
• Brain abscess
• Pyopneumothorax
• pericarditis
Staphylococcal pneumonia
• Treatment
• Hospitalisation
• Oxygen
• IV fluids
• Antibiotics
• Augmentin
• Cloxacillin
• Vancomycin
• Teicoplanin
• Linezolid
• Prolonged therapy 2-6
weeks
Staphylococcal pneumonia
• Complications
• ICD tube for empyema
• May require VATS(video
assisted thoracoscopic
surgery)
• Decortication
H influenzae pneumonia
• < 3months to 3 yrs
• Associated bacteremia
• Begins in nasopharynx
and spreads locally or
through blood
• Fever,dyspnoea,retraction
s
• Course is sub acute and
prolonged
• Treatment –
augmentin/cefotaxime/
• ceftriaxone
Streptococcal pneumonia
• Group A – may follow
measles, varicella,
influenza or pertusis
• Group B – uncommon
in India – important
cause in west(new
borns)
• Interstitial pneumonia
• haemorrhagic
Streptococcal pneumonia
• Fever,chills,dyspnoea,retr
actions
• Cough, blood streaked
sputum
• Pleural effusion
• Interstitial pneumonia
• Leucocytosis
• Sputum microscopy
• Treatment –
penicillin/third generation
cephalosporins - for 7-10
days
Primary atypical pneumonia
• Mycoplasma
pneumoniae
• Chlamydia
• Legionella
• Common in more than
4 yrs of age
• Winter season
• Droplet infetion
• Subclinical mild
infection
Primary atypical pneumonia
• Incubation 12-14 days
• Insidious or abrupt
• Malaise, headache,
fever, sore throat,
myalgia and cough
• Dyspnoea – unusual
• Physical signs are
minimal
Primary Atypical pneumonia
• Difficult to differentiate from viral pneumonia
and rickettesial pneumonia
• Diagnosis is by detection of antibodies by
ELISA/PCR
• Treatment – macrolide antibiotics –
erythromycin/azithromycin/clarithromycin
• Or doxycycline
• For 7 – 10 days
Viral pneumonia
• Diffuse involvement rather than lobar
• RSV common in infants
• Parainfluenza/influenza/adenovirus
• Interstitial pneumonia
• Clinical signs of consolidation are absent
• X ray – perihilar and peribronchial infiltrates
• Supportive treatment
• Ribavirin for RSV
• Oseltamivir – for influenza
Viral pneumonia
COVID 19
• Novel corona virus – detected in wuhan, china in Dec 2019
• Soon spread all over world
• 63 crore people affected so far all over world
• 62 lakh people died officially all over world
• Unofficial ?
• Severe disease less common in healthy children
• Airborne – droplets infection
• Many variants – alpha, beta, gamma, delta, omicron
• Mild cough and cold to Severe acute respiratory syndrome
• RT-PCR/CT Chest/RAT
• Treatment – supportive, oxygen, remdesivir, molnupiravir,
monoclonal antibodies, corticosteroids, IvIg
SARS – CoV 2 (COVID 19)
•THANK YOU

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Pneuminia in children.pptx

  • 1. Pneumonia in children Dr Gururaja R MD,DNB (Paed)
  • 3. Pneumonia - classification • Lobar pneumonia • Bronchopneumonia • Interstitial pneumonia
  • 5. Etiology • Viral – 40% • Bacterial -60% • Viral – RSV, Influenza, parainfluenza, adenovirus • Bacterial - < 2 months – klebsiella, E coli, pneumococci, staphylococci • 3 months to 3 yrs – pneumococci, H influenzae and staphylococci • After 3 yrs – pneumococci and staphylococci
  • 6. Etiology • Chlamydia and mycoplasma – in > 5yrs and adolescents • Pneumocystis jiroveci and Histoplasma in immunocompromised children • Unknown in one third of cases
  • 7. Risk factors • Low birth weight • Malnutrition • Vitamin A deficiency • Lack of breast feeding • Passive smoking • Family history • Air pollution
  • 8. Clinical feaures • Insidious onset • Starts with URTI • FEVER • TACHYPNOEA • DYSPNOEA • RETRACTIONS OF CHEST
  • 10. Pneumococcal pneumonia • Transmitted by droplets • Winter months • Bacteria multiply in alveoli • Inflammatory exudate • Lobar pneumonia • 1-3 days incubation period • Fever, chills, cough, rusty sputum • Tachypnoea, retractions of chest, • Difficulty in feeding, cyanosis • Percussion impaired • Decreased air entry, crepitations and bronchial breathing
  • 11. Pneumococcal pneumonia • Chest x ray • CBC – leucocytosis • Sputum gram staining and culture • Blood culture • Treatment • Penicillin G • Augmentin – (amoxycillin and clavulanate) • Cefotaxime • Ceftriaxone • IV injection – 7 days
  • 12. Staphylococcal pneumonia • Early infancy and childhood • Primary infection of alveoli or secondary to staphylococcal septicaemia • May be complications of measles, influenza • May follow pyoderma • Underlying conditions – cystic fibrosis, DM, malnutrition
  • 13. Staphylococcal pneumonia • Initially diffuse lesions • Lesions suppurate -- brochoalveolar obstruction • Multiple microabscess – erode brochial wall and discharge their contents to bronchi • Pneumatocoeles – pathognomonic finding • Lung abscess • Erodes pleura and pericardium • Empyemia --- < 2yrs is always staphylococcal
  • 15. Staphylococcal pneumonia • Complications • Disseminated disease • Bone, joints infection • Liver abscess • Brain abscess • Pyopneumothorax • pericarditis
  • 16. Staphylococcal pneumonia • Treatment • Hospitalisation • Oxygen • IV fluids • Antibiotics • Augmentin • Cloxacillin • Vancomycin • Teicoplanin • Linezolid • Prolonged therapy 2-6 weeks
  • 17. Staphylococcal pneumonia • Complications • ICD tube for empyema • May require VATS(video assisted thoracoscopic surgery) • Decortication
  • 18. H influenzae pneumonia • < 3months to 3 yrs • Associated bacteremia • Begins in nasopharynx and spreads locally or through blood • Fever,dyspnoea,retraction s • Course is sub acute and prolonged • Treatment – augmentin/cefotaxime/ • ceftriaxone
  • 19. Streptococcal pneumonia • Group A – may follow measles, varicella, influenza or pertusis • Group B – uncommon in India – important cause in west(new borns) • Interstitial pneumonia • haemorrhagic
  • 20. Streptococcal pneumonia • Fever,chills,dyspnoea,retr actions • Cough, blood streaked sputum • Pleural effusion • Interstitial pneumonia • Leucocytosis • Sputum microscopy • Treatment – penicillin/third generation cephalosporins - for 7-10 days
  • 21. Primary atypical pneumonia • Mycoplasma pneumoniae • Chlamydia • Legionella • Common in more than 4 yrs of age • Winter season • Droplet infetion • Subclinical mild infection
  • 22. Primary atypical pneumonia • Incubation 12-14 days • Insidious or abrupt • Malaise, headache, fever, sore throat, myalgia and cough • Dyspnoea – unusual • Physical signs are minimal
  • 23.
  • 24. Primary Atypical pneumonia • Difficult to differentiate from viral pneumonia and rickettesial pneumonia • Diagnosis is by detection of antibodies by ELISA/PCR • Treatment – macrolide antibiotics – erythromycin/azithromycin/clarithromycin • Or doxycycline • For 7 – 10 days
  • 25. Viral pneumonia • Diffuse involvement rather than lobar • RSV common in infants • Parainfluenza/influenza/adenovirus • Interstitial pneumonia • Clinical signs of consolidation are absent • X ray – perihilar and peribronchial infiltrates • Supportive treatment • Ribavirin for RSV • Oseltamivir – for influenza
  • 27.
  • 28. COVID 19 • Novel corona virus – detected in wuhan, china in Dec 2019 • Soon spread all over world • 63 crore people affected so far all over world • 62 lakh people died officially all over world • Unofficial ? • Severe disease less common in healthy children • Airborne – droplets infection • Many variants – alpha, beta, gamma, delta, omicron • Mild cough and cold to Severe acute respiratory syndrome • RT-PCR/CT Chest/RAT • Treatment – supportive, oxygen, remdesivir, molnupiravir, monoclonal antibodies, corticosteroids, IvIg
  • 29. SARS – CoV 2 (COVID 19)