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10Cutaneous Tuberculosis.ppt
1.
2. Relatively uncommon form of extra pulmonary
tuberculosis
Incidence is rising recently due to HIV pandemic
Caused by M.tuberculosis or rarely by M.bovis
Clinical feature depends on the host immunity
and the route of infection and classified as
primary or postprimary skinTB.
3. The result of the inoculation the bacilli into the
skin of an individual without immunity.
It enters the skin through abrasions and minor
injuries.
The early lesion is a nondescript, brownish
papule or nodule, or a ragged ulcer with an
undermined edge and a granular hemorrhagic
base.
In time, the edge becomes firmer, and a thin
adherent crust develops.
4. Ulcerated and edematous mucosal lesions may
also be seen.
The chancre will heal slowly, taking many
months, may proceed to lupus vulgaris or rarely
to miliaryTB
5.
6.
7. An indolent, warty, plaque-like form
occurring as a result of the inoculation of
organisms into the skin of a previously
infected patient.
Starts as a small, symptomless, indurated,
warty papule with a slight inflammatory
areola.
By gradual extension, a verrucose plaque is
formed.
8. Deeply destructive papillomatous and
sclerotic forms may cause deformity of the
limbs.
The condition responds to antituberculosis
treatment; without it, extension is usually
extremely slow and lesions may remain
virtually inactive for months or years
9.
10.
11.
12.
13.
14.
15. Results from the involvement and breakdown
of the skin overlying a contiguous
tuberculosis focus.
Numerous fistulae may intercommunicate
beneath ridges of a bluish skin.
Progression and scarring produce irregular
adherent masses.
16.
17.
18.
19.
20. A chronic progressive post-primary form of
cutaneous tuberculosis occurring in a person
with a moderate or high degree of immunity.
It originates from underlyingTB foci
It can also arise after exogenous inoculation
or as a complication of BCG vaccination.
21. Most of the cases occur in the head and neck.
Mucosa may be involved.
22.
23.
24.
25.
26. Metastatic tuberculous abscess.
The result of haematogenous dissemination
from a primary focus during periods of lowered
resistance.
Manifests as single or multiple subcutaneous
nodule or fluctuant abscess.
27.
28.
29. Xcis T. Chancre T.Verrucosa
cutis
Lupus
vulgaris
T.
Colliquativa
cutis
T. Guma
Primary site
of infection
Inoculation
to skin
Inoculation
to skin
underlying
TB foci/
exogenous
inoculation/
BCG vaccine
Breakdown
of skin
overlyingTB
foci
Heamatoge
neous
disseminati
on
Immunity Without
immunity
Pt is
previously
infected
Post
primary-
already
infected
Post
primary
Post
primary
Clinical
signs
Brownish
papule or
nodule,
ragged
ulcer
Warty
papule or
plaque,
destruction/
deformity
Mainly on
head and
neck
Inter
communicat
ing fistulae,
scarring
Subcutaneo
us nodules
or fluctuant
abscesses
30. Non tuberculous mycobacterial infection
caused by M.ulcerans.
Infection is acquired from contaminated soil.
Starts as small painless intradermal nodule on
the extremity that gradually extends to form
irregular shalow necrotic ulcer that may reach
several centimeters
Constitutional symptoms are typically absent.