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PILOSEBACEOUS
DISORDERS
Acne Vulgaris
An inflammation of the pilosebaceous units of certain body
Multifactorial cause speculated
◦ Occupation
◦ Drugs
◦ Genetic Aspects
◦ Endocrine factors
◦ Emotional stress
◦ Occlusion and pressure
◦ Propionibacterium acnes
Acne Vulgaris
Comedonal Acne (Acne Vulgaris)
◦Small deeper elevation near a hair follicle.
◦Two types exist
◦Open (blackheads)
◦Closed (whiteheads)
Acne Vulgaris
Papulopustular acne
◦Red or skin colored papules and larger
pastules
Acne Vulgaris
Acne Vulgaris
Nodulocystic Acne
◦Nodules, noduloulcerative lesions, or cysts
◦Draining sinuses are seen
Scars may be seen in all types
Acne Vulgaris
Acne Vulgaris
Severe acne
◦persistent or recurrent inflammatory nodules
◦extensive papulopustular lesions,
◦active scarring, and/or presence of sinus tracts.
Acne Vulgaris
Acne in the Adult Woman
Acne Conglobata
Acne Fulminans
Treatment
Mild Acne
Topical antibiotics (clindamycin and
erythromycin)
Benzoyl peroxide gels (2 %, 5 %)
Topical retinoids (tretinoin)
Treatment
Moderate Acne:
Oral tetracyclines added to the preceding
regimen
Treatment
Severe Acne:
Isotretinoin 0.5 to 2mg/kg given
with food for 15 to 20 weeks
Rosacea
A chronic acneform disorder of the facial pilosebaceous units
Cause not clearly known
It is though to be disease of the capillaries than the glands
Comedones are absent
Rosacea
Patients feel “hot” on the face when stimulated by heat, spicy food,
stress etc.
Four stages:
◦ Stage 0
◦ Stage I
◦ Stage II
◦ Stage III
Rosacea
Rhinophyma is more common in
males
Corneal ulceration may occur in
severe cases
Rosacea
Treatment:
Reduction or elimination of aggravating
factors
Topical: Metronidazole
Systemic: Tetracycline
Prolonged treatment is needed
Perioral Dermatitis
Pesky facial dermatosis occurring mainly in young women
Cause not known
Discrete erythematous micropapules perioraly.
Rim of sparing around the vermilion border of lips.
There are no comedones.
Perioral Dermatitis
Topical: Metronidazole or erythromycin
Systemic: Minocycline, Doxycycline or
Tetracycline
Prognosis is generally good.

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13Pilosbaceous disorders.ppt