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Health Institutions:
Type of Health Facilities:
a) Primary Health Care Facilities (more detailed in attached file):
Health Unit: The Health Unit (HU) represents the first level of the health
system and it is considered the first contact level between the service
provider and the client. The HU provides mainly preventive services and
health education, but also some limited services of very basic curative care.
More complicated cases are referred to the next Health Centre or District
Hospital. The HU provides its services to a catchment area of approximately
1,000-5,000 population.
Health Center including Motherhood & Childhood center: The Health
Centre (HC) represents the second level of the health system and serves a
catchment area of 5,000-20,000 population. It provides the same PHC
services as the HU. But in addition it provides basic diagnostic (laboratory)
and a wider range of curative services, including minor operations such as
surgical incision of abscesses under local anaesthesia, dressing, etc. The HC
receives referred cases from HU and itself refers complicated cases to the
District Hospital.
3. District Health Hospital:
The District Hospital (DH) represents the third level of the health system
and serves a catchment area of 60,000-150,000 population. It provides
all the services, which are delivered at the HC, but at a larger scale. In
addition, it provides life-saving emergency surgical operations, blood
transfusion services, and inpatient services. The standard district
hospital has four departments: internal medicine, pediatrics, gyn-
obstetrics and surgery. The district hospital is the referral centre for
surrounding HCs and also supervises these HCs. The DH refers cases of
complexity exceeding its capacity to the next higher level.
b)Curative Facilities:
1.General Hospital
2.Specialized Hospital
3.Motherhood & Childhood Hospital.
Job Description of some health staff:
1.General Medical Doctor (Physician): ► CHILD HEALTH : IMCI, ►
WOMEN’S REPRODUCTIVE HEALTH: FP, ANC, Safe Delivery, Post-
Natal Care, STDs, ► MANAGEMENT OF COMMUNICABLE
DISEASES: TB / DOTS, Leprosy, Malaria, Bilharziasis / Helminthiasis,
Hepatitis,► MANAGEMENT OF NON-COMMUNICABLE DISEASES:
Hypertension, Diabetes, ► PRIMARY EYE CARE, ► SKIN INFECTION
MANAGEMENT,► MEDICAL & SURGICAL EMERGENCIES: Injuries
(accidents, bullets), Animal bites, Shocks, Burns, Acute Abdomen,
► MINOR SURGERY: Circumcision, Abscess incision / drainage,
Health education
2. Doctor Assistant: he provide the following preventive and curative services:
provide all PHC services including vaccination, ► CHILD HEALTH : IMCI,►
MANAGEMENT OF COMMUNICABLE DISEASES: TB / DOTS, Leprosy, Malaria,
Bilharziasis / Helminthiasis, Hepatitis,► If the medical doctor is unavailable he
provide MANAGEMENT(follow up) OF NON-COMMUNICABLE DISEASES:
Hypertension, Diabetes, ► PRIMARY EYE CARE, ► SKIN INFECTION
MANAGEMENT,► If the medical doctor is unavailable he provide MEDICAL &
SURGICAL EMERGENCIES (first Aids): Injuries (accidents, bullets), Animal bites,
Shocks, Burns, Acute Abdomen, ► MINOR SURGERY: Circumcision, Abscess incision
/ drainage, Health education, referring complicated cases to doctors, participate in
health campaigns, Nutrition management.
3. Nurse: the same like Doctor Assistant.
4. Midwife: ► WOMEN’S REPRODUCTIVE HEALTH: FP, ANC, Safe Delivery, Post-
Natal Care, STDs, Health education, Nutrition management for women, discovering
and referring pregnant women with danger signs, Home Based Care for mother and
child, Newborn Resuscitation, Perform basic EmOC services, Vaccination services for
Mother and Child.
10/1/2022 Human Resources 6
What are our basic HR
objectives?

Is equitably distributed – rural vs urban

Is efficiently used – balance of MD and
paraprofessionals, PHC vs hospital

Has Appropriate skills (quality)

both clinical and administrative

Is motivated to solve problems at each level

Follows rules and standards (“good agents”)
10/1/2022 Human Resources 7
HR Management Systems Problems

Alignment of staff with organizational structure

Hiring, Promoting, Firing and Transfers

Migration and Premature Death

Incentives for improving performance

Training

HR Planning

Conflict Resolution Mechanisms
10/1/2022 Human Resources 8
Staffing Organizational Structure

Are staff with the right skills in the right
organizational units?

Is there a critical mass of skilled people in each
organizational unit?

Colombia example of “Analytical” Unit

What to do about “over staffing”?

How do you know?

Golden handshakes?
10/1/2022 Human Resources 9
Hiring and Recruitment

How do you avoid patronage and create merit hiring
process?

What pre service training requirements are
appropriate?

What is role of Civil Service regulations?

Permanent vs. Contract staffing?

Current skill level in national or local labor pool?
10/1/2022 Human Resources 10
Migration and Premature Death

Shortage of nurses in English speaking countries often
due to migration to U.S., Britain, South Africa

HIV/AIDS deaths of health workers are creating a
crisis in high incidence countries in Africa
10/1/2022 Human Resources 11
Promotions and Career Paths

How can you design promotion procedures that are
fair and related to performance vs. allowing unfair
favoritism or simple longevity?

Defined steps and opportunities for career
advancement?

Docs as administrators?

Hospital administrators as career?
10/1/2022 Human Resources 12
Disciplining and firing

Civil service rules usually restrict management options
to extreme cases

Unions usually defend workers

Accepted practice vs. enforcing regulations – case of
the absent doctors
10/1/2022 Human Resources 13
Transfers, maternity leave and vacations

Who controls transfers? Local or central?

Who initiates transfers? Staff or management?

How can transfers, vacations and maternity leave be
replaced?
10/1/2022 Human Resources 14
Incentives in large organizations

Monetary

Salary scale – tends to reward longevity more than skills and
performance

Benefits – pensions, insurance

Bonus – can be tied to performance

Performance increases for groups vs individuals

Problem of declining budgets and increasing
percentage allotted to salaries

Problem of competition with private sector for
providers and effect on salaries and hours
10/1/2022 Human Resources 15
Incentives in Large Organizations

Non-monetary

Housing, schooling, other benefits

Promotion opportunities

Training opportunities

Symbolic rewards

Problem of Incentives for Rural Service

Restrictions of Labor Laws and Civil Service
10/1/2022 Human Resources 16
Pre-service training/education

Quality of training institutions – accreditation and
explosion of private sector

Job descriptions usually define requirements for
providers but seldom for administrative positions

MOH does usually not control medical schools but
often does control nursing and non-professional staff
schools

Rural schools to “keep ‘em down on the farm”
10/1/2022 Human Resources 17
In-service training

Upgrade current skill levels – continuing training

“too much training” disrupts service

Local capacity to provide training

Cascade system, training of trainers
10/1/2022 Human Resources 18
HR Planning

PAHO/”Stalinist” Planning Models

Plan for large public sector

Model of population based “needs” dictates hiring and
training planning

i.e. # MD per population or # nurses per MD

Thomas Hall’s planning model

Software to estimate both supply and demand

Only for public sector planning

How to plan for dynamic public/private system?

US failure: planning model leads to oversupply of MD
10/1/2022 Human Resources 19
Conflict Resolution Mechanisms

Define clearly responsibilities and roles

Transparency of recruitment, promotion, and
disciplinary processes

Role of unions

Politicization of labor conflicts is often the downfall of
ministers
HEALTH Economic
• Cost Minimization Analysis (CMA): Comparison of costs of different
interventions that are assumed to provide equivalent benefits
• Cost Effectiveness Analysis (CEA): Benefits are measured in natural units (e.g.
Life years gained, heart attacks avoided)
– CEA is an expression of the desired effect of a programme, service, institution or
support activity in reducing a health problem
– CEA measures the degree of attainment of pre-determined objectives and targets
– Most comprehensive indicator of CEA: Quality adjusted life years (QALYs)
gained
• Cost Utility Analysis (CUA): Comparison of costs and benefits of health
technologies that impact both quality and quantity of life
– CUA measures health benefits as healthy years; QALYs, DALYs (Disability
adjusted life years), healthy year equivalent are used
– CUA is multi-dimensional
– Most widely used measure of benefit in CUA: Quality adjusted life years
(QALYs)
• Cost Benefit Analysis (CBA): Benefits are measured in monetary terms
– Human capital approach
– Willingness to pay approach 20
• Cost Accounting: A quantitative management technique which provides basic
data on cost structure of any programme
• Input-Output Analysis: An economic technique which enables calculations to be
made of the effects of changing the inputs
• Network Analysis: Is the graphic plan of all events and activities to be completed
in order to reach an end objective
– Programme Evaluation and Review Technique (PERT): An arrow diagram
representing the logical sequence in which events must take place. It aids in
planning, scheduling and monitoring the project; allows better communication
between various levels and helps furnish timely, updated progress reports
– Critical Path Method (CPM): The ‘longest path’ of the network is called as
critical path. If any activity along the critical path is delayed, entire project will be
delayed
• Systems Analysis: Is a management technique of finding out the cost-
effectiveness of the available alternatives
• Planning Programming Budgeting System (PPBS): It helps decision makers to
allocate resources so as to help achieve objectives in the most efficient way
– It allows grouping of activities related to each objective
– Zero Budget Approach: All budgets start at zero and no one gets any budget that
he cannot specifically justify on a year-to-year basis
• Work Sampling: Systematic observation and recording of activities of one or
more individuals, carried out at pre-determined or random intervals
– It provides quantitative measurement of various activities 21
Environmental Health
INTRODUCTION

Most diseases caused by or influenced by
environmental factors.

Estimated that 80% of all cancers are caused by
pollutants in:

Air.

Water.

Food.

Climate.

Space.
22
INTRODUCTION

Environmental epidemiology provides scientific basis
for studying and interpreting the relations between
sanitation
hygiene
air/water/soil
food
fast foods
tobacco
alcohol
house/office
leisure
NCD
malformation
effect
behaviour
KAP
23
Environmental Factor

Accident factor

Hazard situation, speed, work load, chemicals.

Physical factor

Noise, climates, work load, light, radiation.

Chemical factor

Chemicals, drugs, skin irritants, food addictive

Biological factor

Bacteria, virus, parasites, protozoa, helminthes.

Psychological factor

Stress, shift work, pay, human relationship.
24

Factors that modify the effect of environmental factors

Genetic (5%).

Gender.

Age.

Physical condition.

Personality.

Nutrition.

Disease.
25
ENVIRONMENTAL
EPIDEMIOLOGY

Definition:
Application of concept and method of epidemiology in
investigating and assessing any possible
environmental hazards to be used in prevention and
control through evaluation.
26

National Research Council (1991):
The study of the effect on human health of
physical, biologic, and chemical factors in the
external environment.
27
WHO

Implement epidemiologic studies of the health
effects of chemical and physical hazards in the
environment

Asbestos.

Toxic metals and pesticides.

Air pollutants.

Solvents.
28
WHO

Provide consultant support and assist in developing
technical information and guidance material on
environmental epidemiology.

Training activities and collaborate in transferring
information and methods.
29
WHO

Geneva from 7 – 13 October 1975:

Produced “Guidelines on Studies in Environmental
Epidemiology”.
30
FOCUS
DEVELOPED COUNTRY

Smoking.

Occupational hazard.

Toxic metal pollution (l
ead).

Air pollution.
DEVELOPING COU
NTRY

Sanitation.

Communicable di
seases.

Water pollution.

Air pollution.
31
CHRONIC DISEASES

Congenital malformation (
60% unknown cause).

Adult-onset asthma.

Chronic respiratory diseas
es.

Kidney problem.

Liver problem.

Endometriosis.

Onset of menses.

Onset of menopause.

Obesity.

Cardiovascular disease
s.

Cerebrovascular diseas
es.
32

Smallpox (WHO 1967 – at 31 countries)

10 to 15 million new cases.

2 million death.

Methyl-mercury poisoning

Minamata Bay, Kyushu Island, Japan (1950’s)

Rheumatic fever.

Smoking / asbestos and lung cancer.

AIDS.
33
METHOD

Appropriate methods or study design:

Case study.

Case series.

Cross sectional study.

Case-control study.

Cohort.

Randomized clinical trial.

Animal study.
34

Limitations:

Small number of expose people.

Agent still under research investigation.

Only small increase of risk.

Result is not inferable to other subject.

Co incidence.
35
EXPOSURE

Complete data and information:

Exposure history (concentration, duration,
frequency).

Pre and post exposure health problems.

Route of exposure (inhalation, ingestion, skin).

Ratio of absorption (body weight).

Half life of the substance.

Measure metabolites.
36
HEALTH IMPACT

Identify health implication due to the exposure:

Illness

Acute.

Chronic.

Biological markers

Chronic diseases.

Exposure assessment.
37
RISK ASSESSMENT

Present of risk or not.

Decreasing of 37% mean population blood lead due to
reducing usage of leaded petrol.

An increase of 2.5 times mortality rate during fog
episode in London 1952.

Risk communication.

Hazard index:
< 1

Acceptable cancer risk: 1 : 1 000 000 population.
38

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Community Medicine-1.ppt

  • 1. Health Institutions: Type of Health Facilities: a) Primary Health Care Facilities (more detailed in attached file): Health Unit: The Health Unit (HU) represents the first level of the health system and it is considered the first contact level between the service provider and the client. The HU provides mainly preventive services and health education, but also some limited services of very basic curative care. More complicated cases are referred to the next Health Centre or District Hospital. The HU provides its services to a catchment area of approximately 1,000-5,000 population. Health Center including Motherhood & Childhood center: The Health Centre (HC) represents the second level of the health system and serves a catchment area of 5,000-20,000 population. It provides the same PHC services as the HU. But in addition it provides basic diagnostic (laboratory) and a wider range of curative services, including minor operations such as surgical incision of abscesses under local anaesthesia, dressing, etc. The HC receives referred cases from HU and itself refers complicated cases to the District Hospital.
  • 2. 3. District Health Hospital: The District Hospital (DH) represents the third level of the health system and serves a catchment area of 60,000-150,000 population. It provides all the services, which are delivered at the HC, but at a larger scale. In addition, it provides life-saving emergency surgical operations, blood transfusion services, and inpatient services. The standard district hospital has four departments: internal medicine, pediatrics, gyn- obstetrics and surgery. The district hospital is the referral centre for surrounding HCs and also supervises these HCs. The DH refers cases of complexity exceeding its capacity to the next higher level. b)Curative Facilities: 1.General Hospital 2.Specialized Hospital 3.Motherhood & Childhood Hospital.
  • 3. Job Description of some health staff: 1.General Medical Doctor (Physician): ► CHILD HEALTH : IMCI, ► WOMEN’S REPRODUCTIVE HEALTH: FP, ANC, Safe Delivery, Post- Natal Care, STDs, ► MANAGEMENT OF COMMUNICABLE DISEASES: TB / DOTS, Leprosy, Malaria, Bilharziasis / Helminthiasis, Hepatitis,► MANAGEMENT OF NON-COMMUNICABLE DISEASES: Hypertension, Diabetes, ► PRIMARY EYE CARE, ► SKIN INFECTION MANAGEMENT,► MEDICAL & SURGICAL EMERGENCIES: Injuries (accidents, bullets), Animal bites, Shocks, Burns, Acute Abdomen, ► MINOR SURGERY: Circumcision, Abscess incision / drainage, Health education
  • 4. 2. Doctor Assistant: he provide the following preventive and curative services: provide all PHC services including vaccination, ► CHILD HEALTH : IMCI,► MANAGEMENT OF COMMUNICABLE DISEASES: TB / DOTS, Leprosy, Malaria, Bilharziasis / Helminthiasis, Hepatitis,► If the medical doctor is unavailable he provide MANAGEMENT(follow up) OF NON-COMMUNICABLE DISEASES: Hypertension, Diabetes, ► PRIMARY EYE CARE, ► SKIN INFECTION MANAGEMENT,► If the medical doctor is unavailable he provide MEDICAL & SURGICAL EMERGENCIES (first Aids): Injuries (accidents, bullets), Animal bites, Shocks, Burns, Acute Abdomen, ► MINOR SURGERY: Circumcision, Abscess incision / drainage, Health education, referring complicated cases to doctors, participate in health campaigns, Nutrition management. 3. Nurse: the same like Doctor Assistant. 4. Midwife: ► WOMEN’S REPRODUCTIVE HEALTH: FP, ANC, Safe Delivery, Post- Natal Care, STDs, Health education, Nutrition management for women, discovering and referring pregnant women with danger signs, Home Based Care for mother and child, Newborn Resuscitation, Perform basic EmOC services, Vaccination services for Mother and Child.
  • 5.
  • 6. 10/1/2022 Human Resources 6 What are our basic HR objectives?  Is equitably distributed – rural vs urban  Is efficiently used – balance of MD and paraprofessionals, PHC vs hospital  Has Appropriate skills (quality)  both clinical and administrative  Is motivated to solve problems at each level  Follows rules and standards (“good agents”)
  • 7. 10/1/2022 Human Resources 7 HR Management Systems Problems  Alignment of staff with organizational structure  Hiring, Promoting, Firing and Transfers  Migration and Premature Death  Incentives for improving performance  Training  HR Planning  Conflict Resolution Mechanisms
  • 8. 10/1/2022 Human Resources 8 Staffing Organizational Structure  Are staff with the right skills in the right organizational units?  Is there a critical mass of skilled people in each organizational unit?  Colombia example of “Analytical” Unit  What to do about “over staffing”?  How do you know?  Golden handshakes?
  • 9. 10/1/2022 Human Resources 9 Hiring and Recruitment  How do you avoid patronage and create merit hiring process?  What pre service training requirements are appropriate?  What is role of Civil Service regulations?  Permanent vs. Contract staffing?  Current skill level in national or local labor pool?
  • 10. 10/1/2022 Human Resources 10 Migration and Premature Death  Shortage of nurses in English speaking countries often due to migration to U.S., Britain, South Africa  HIV/AIDS deaths of health workers are creating a crisis in high incidence countries in Africa
  • 11. 10/1/2022 Human Resources 11 Promotions and Career Paths  How can you design promotion procedures that are fair and related to performance vs. allowing unfair favoritism or simple longevity?  Defined steps and opportunities for career advancement?  Docs as administrators?  Hospital administrators as career?
  • 12. 10/1/2022 Human Resources 12 Disciplining and firing  Civil service rules usually restrict management options to extreme cases  Unions usually defend workers  Accepted practice vs. enforcing regulations – case of the absent doctors
  • 13. 10/1/2022 Human Resources 13 Transfers, maternity leave and vacations  Who controls transfers? Local or central?  Who initiates transfers? Staff or management?  How can transfers, vacations and maternity leave be replaced?
  • 14. 10/1/2022 Human Resources 14 Incentives in large organizations  Monetary  Salary scale – tends to reward longevity more than skills and performance  Benefits – pensions, insurance  Bonus – can be tied to performance  Performance increases for groups vs individuals  Problem of declining budgets and increasing percentage allotted to salaries  Problem of competition with private sector for providers and effect on salaries and hours
  • 15. 10/1/2022 Human Resources 15 Incentives in Large Organizations  Non-monetary  Housing, schooling, other benefits  Promotion opportunities  Training opportunities  Symbolic rewards  Problem of Incentives for Rural Service  Restrictions of Labor Laws and Civil Service
  • 16. 10/1/2022 Human Resources 16 Pre-service training/education  Quality of training institutions – accreditation and explosion of private sector  Job descriptions usually define requirements for providers but seldom for administrative positions  MOH does usually not control medical schools but often does control nursing and non-professional staff schools  Rural schools to “keep ‘em down on the farm”
  • 17. 10/1/2022 Human Resources 17 In-service training  Upgrade current skill levels – continuing training  “too much training” disrupts service  Local capacity to provide training  Cascade system, training of trainers
  • 18. 10/1/2022 Human Resources 18 HR Planning  PAHO/”Stalinist” Planning Models  Plan for large public sector  Model of population based “needs” dictates hiring and training planning  i.e. # MD per population or # nurses per MD  Thomas Hall’s planning model  Software to estimate both supply and demand  Only for public sector planning  How to plan for dynamic public/private system?  US failure: planning model leads to oversupply of MD
  • 19. 10/1/2022 Human Resources 19 Conflict Resolution Mechanisms  Define clearly responsibilities and roles  Transparency of recruitment, promotion, and disciplinary processes  Role of unions  Politicization of labor conflicts is often the downfall of ministers
  • 20. HEALTH Economic • Cost Minimization Analysis (CMA): Comparison of costs of different interventions that are assumed to provide equivalent benefits • Cost Effectiveness Analysis (CEA): Benefits are measured in natural units (e.g. Life years gained, heart attacks avoided) – CEA is an expression of the desired effect of a programme, service, institution or support activity in reducing a health problem – CEA measures the degree of attainment of pre-determined objectives and targets – Most comprehensive indicator of CEA: Quality adjusted life years (QALYs) gained • Cost Utility Analysis (CUA): Comparison of costs and benefits of health technologies that impact both quality and quantity of life – CUA measures health benefits as healthy years; QALYs, DALYs (Disability adjusted life years), healthy year equivalent are used – CUA is multi-dimensional – Most widely used measure of benefit in CUA: Quality adjusted life years (QALYs) • Cost Benefit Analysis (CBA): Benefits are measured in monetary terms – Human capital approach – Willingness to pay approach 20
  • 21. • Cost Accounting: A quantitative management technique which provides basic data on cost structure of any programme • Input-Output Analysis: An economic technique which enables calculations to be made of the effects of changing the inputs • Network Analysis: Is the graphic plan of all events and activities to be completed in order to reach an end objective – Programme Evaluation and Review Technique (PERT): An arrow diagram representing the logical sequence in which events must take place. It aids in planning, scheduling and monitoring the project; allows better communication between various levels and helps furnish timely, updated progress reports – Critical Path Method (CPM): The ‘longest path’ of the network is called as critical path. If any activity along the critical path is delayed, entire project will be delayed • Systems Analysis: Is a management technique of finding out the cost- effectiveness of the available alternatives • Planning Programming Budgeting System (PPBS): It helps decision makers to allocate resources so as to help achieve objectives in the most efficient way – It allows grouping of activities related to each objective – Zero Budget Approach: All budgets start at zero and no one gets any budget that he cannot specifically justify on a year-to-year basis • Work Sampling: Systematic observation and recording of activities of one or more individuals, carried out at pre-determined or random intervals – It provides quantitative measurement of various activities 21
  • 22. Environmental Health INTRODUCTION  Most diseases caused by or influenced by environmental factors.  Estimated that 80% of all cancers are caused by pollutants in:  Air.  Water.  Food.  Climate.  Space. 22
  • 23. INTRODUCTION  Environmental epidemiology provides scientific basis for studying and interpreting the relations between sanitation hygiene air/water/soil food fast foods tobacco alcohol house/office leisure NCD malformation effect behaviour KAP 23
  • 24. Environmental Factor  Accident factor  Hazard situation, speed, work load, chemicals.  Physical factor  Noise, climates, work load, light, radiation.  Chemical factor  Chemicals, drugs, skin irritants, food addictive  Biological factor  Bacteria, virus, parasites, protozoa, helminthes.  Psychological factor  Stress, shift work, pay, human relationship. 24
  • 25.  Factors that modify the effect of environmental factors  Genetic (5%).  Gender.  Age.  Physical condition.  Personality.  Nutrition.  Disease. 25
  • 26. ENVIRONMENTAL EPIDEMIOLOGY  Definition: Application of concept and method of epidemiology in investigating and assessing any possible environmental hazards to be used in prevention and control through evaluation. 26
  • 27.  National Research Council (1991): The study of the effect on human health of physical, biologic, and chemical factors in the external environment. 27
  • 28. WHO  Implement epidemiologic studies of the health effects of chemical and physical hazards in the environment  Asbestos.  Toxic metals and pesticides.  Air pollutants.  Solvents. 28
  • 29. WHO  Provide consultant support and assist in developing technical information and guidance material on environmental epidemiology.  Training activities and collaborate in transferring information and methods. 29
  • 30. WHO  Geneva from 7 – 13 October 1975:  Produced “Guidelines on Studies in Environmental Epidemiology”. 30
  • 31. FOCUS DEVELOPED COUNTRY  Smoking.  Occupational hazard.  Toxic metal pollution (l ead).  Air pollution. DEVELOPING COU NTRY  Sanitation.  Communicable di seases.  Water pollution.  Air pollution. 31
  • 32. CHRONIC DISEASES  Congenital malformation ( 60% unknown cause).  Adult-onset asthma.  Chronic respiratory diseas es.  Kidney problem.  Liver problem.  Endometriosis.  Onset of menses.  Onset of menopause.  Obesity.  Cardiovascular disease s.  Cerebrovascular diseas es. 32
  • 33.  Smallpox (WHO 1967 – at 31 countries)  10 to 15 million new cases.  2 million death.  Methyl-mercury poisoning  Minamata Bay, Kyushu Island, Japan (1950’s)  Rheumatic fever.  Smoking / asbestos and lung cancer.  AIDS. 33
  • 34. METHOD  Appropriate methods or study design:  Case study.  Case series.  Cross sectional study.  Case-control study.  Cohort.  Randomized clinical trial.  Animal study. 34
  • 35.  Limitations:  Small number of expose people.  Agent still under research investigation.  Only small increase of risk.  Result is not inferable to other subject.  Co incidence. 35
  • 36. EXPOSURE  Complete data and information:  Exposure history (concentration, duration, frequency).  Pre and post exposure health problems.  Route of exposure (inhalation, ingestion, skin).  Ratio of absorption (body weight).  Half life of the substance.  Measure metabolites. 36
  • 37. HEALTH IMPACT  Identify health implication due to the exposure:  Illness  Acute.  Chronic.  Biological markers  Chronic diseases.  Exposure assessment. 37
  • 38. RISK ASSESSMENT  Present of risk or not.  Decreasing of 37% mean population blood lead due to reducing usage of leaded petrol.  An increase of 2.5 times mortality rate during fog episode in London 1952.  Risk communication.  Hazard index: < 1  Acceptable cancer risk: 1 : 1 000 000 population. 38