11. HMD
• Common in preterm babies<34 weeks
• 10-15% over all incidence
• > 80% in less than 28 weeks
• Immature lung
• Surfactant deficiency
12.
13. Surfactant
• Phospholipid
• Produced by type 2 alveolar cells
• Reduces surface tension in alveoli
• Production starts at 20 weeks and peaks 35
weeks
• In its absence – alveoli collapse
• Hypoxia
• Increased work of breathing
• Respiratory failure