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• Morning meeting
DR IRFAN ALI
fcps trainee
NURSERY
BIODATA
• B/O HUMAIRA
• DOB : 16th July 2016
• TOB :10 30 AM
• DOA : 1st August 2016
• DO L : 16th
• GENDER :FEMALE
• ADDRESS: SHIKARPUR
• c/o
Respiratory distress since 1st day of life
BIRTH HISTORY
• ANTENATAL HISTORY
23 yrs old mother
primigravida
38 week of gestation.
Booked case.
TT received.
U/S done
Multivitamin taken.
No h/o PROM
Prolong labour.
H/o fever 2 days before c-section.
• NATAL HISTORY
C-Section at 38 weeks
Hospital delivery,
• POSTNATAL HISTORY
• Cried immediately
• No history of resuscitation at birth
• First urine and stool passed within 24 hours.
• Vitamin k received.
• h/o respiratory distress
• FAMILY HISTORY
1st issue of non consanguineous marriage.
No h/o any significant illness in family.
• SOCIOECONOMIC HISTORY
Belongs to a poor class family. father is
unemployed and lives in house of 2 ventilated rooms
Examination
• sick looking neonate lying in incubator with visible distress.
H/r : 158 b /min
R/r : 73 br/min
Temp: a/f
Oxygen saturations : 95 % at room air
J-, A-, Cy- ,D- ,E-
Anthropometry
Weight 3 kg (50th centile)
Length 49 cm (b/w 75th and 50th centile)
foc 34 cm (b/w 75th and 50th centile)
Systemic examination
• Chest :
: tachypnea,
sternal subcostal and intercostal retractions, nasal
flaring,
b/l crepts audible.
• CVS : S 1 + S 2 + no added sounds
CRT 2 Sec
• Abdomen : soft NVM present, GS audible
• Genitals : female normal genitalia
• Anus: patent
• SKIN: Normal
• Back : Normal
• CNS :
• Fontanelle open and flat
• Moro:
• Sucking :
• Grasp : fair
• Rooting :
• Pupils: bilaterally equal and reactive to light.
Head to toe examination
• Normal with no dysmorphic features.
Provisional diagnosis
• TERM/ AGA/ NBW
• congenital pneumonia
• PPHN
Management
• Admited in nicu
• Incubator care
• Oxygen support via cpap.
• n/g tube passed
• NPO till further orders
• X-ray chest
• echo
• Investigations
• Maintainance fluids
• Iv antibiotics started.
Investigations
CBC 18-7-16 20-7-16 22-7-16
Hb
MCV
MCH
MCHC
15.5 g/dl
91 fl
32 pg
33 g/dl
14 g/dl 16.2 g/dl
WBCs 9,700 15,100 13,000
N 70%
(ANC=6790)
77 %
(ANC=11,627)
65 %
(ANC=8450)
L 2O% 15% 28 %
M 08% 5 % 05 %
E 02% 3 % 02%
PLATELETS 163,000 152,000 157,000
uce 20-7-16 22-7-16
urea 40 mg/dl 65 mg/dl
Cr 0.6 mg/dl 0.8 mg/dl
Na 135 mEq/L
K 5.12 mEq/L
Cl 102 mEq/L
• RBS : 100 mg/ dl at the time of presentation
serial monitoring remained normal
• BBG :B positive
Blood c/s; awaited
cxr
Hospital course
• Monitoring of vitals and RBS done
• oxygen support continued
• Preductal and postductal spo2 was 95%.
• Antibiotics changed
 Condition gradually improved
 Oxygen tapered kept on headbox support
• Activity improved
• N/G feeding started
• Planned to dmf and step down
Repeat labs
4-8-16 8-8-16
CBC
Hb
MVC
MCH
MCHC
13.5 g/dl
82 fl
26 pg
31 g/dl
13 g/dl
85 fl
25 pg
30 g/dl
WBCs 7,500 6,200
N 60 %
(ANC=4500)
64 %
(ANC=3968)
L 36 % 33 %
M 02 % 01 %
E 02 % O2 %
PLATELETS 182,000 2,94,000
UCE 04-08-16 08-08-16
Urea 13 26
Cr 0.4 01
Na 140 138
K 5.5 5.6
Cl 101 103
FINAL DAIGNOSIS
• TERM/ AGA/ NBW
• Congenital pneumonia
• AN APPROACH TO RESPIRATORY DISTRESS IN
NEONATES
PLAN
• Introduction
• Causes and
Classification
• Respiratory
Distress Signs
• Evaluation and
Investigation
• General
Management
Introduction
Respiratory Distress in Newborn
= Abnormal respiratory signs in neonates
Causes and Classification
Respiratory
Distress in
Newborn
Causes
Respiratory
Extrapulmonary
Management
Medical
Surgical
Causes
Respiratory
Extrapulmonary
Upper Airway
Obstruction
Choanal
Atresia
Pierre Robin
Sequence
Laryngeal
pathology
Lower Airway
TTN
RDS/HMD
MAS
Congenital
Pneumonia
Air Leak
Syndrome
Milk
Aspiration
Rib cage
anomalies
Congenital
Diaphragmatic
Hernia
Neuromuscular
diseases
PPHN
Congenital
Heart Diseases
Shock Anaemia Polycythaemia
Hypoglycaemia Hypothermia
Metabolic
acidosis
Intracranial
Birth Trauma/
Encephalopathy
Management
Medical
• TTN
• MAS
• RDS/HMD
• Pneumonia
• Milk Aspiration
• CHD
• Shock
• Anaemia
• Polycythaemia
• Hypoglycaemia
• Hypothermia
• Metabolic Acidosis
Surgical
• Choanal atresia
• Pierre Robin Sequence
• Air Leak Syndrome
• Rib cage anomalies
• Congenital Diaphragmatic Hernia
• Air Leak Syndrome
• Intracranial Birth Trauma/
Encephalopathy
Respiratory Distress Signs
Respiratory
Distress in
Newborn
Tachypnoea
Retractions
Grunting
Nasal
Flaring
Cyanosis
Tachypnoea
Respiratory Rate:
up to 2 months:
60 or more
2 to 12 months:
50 or more
12 months to 5 years:
40 or more
Retractions
• Due to negative intrapleural
pressure generated
between the contraction of
diaphragm, respiratory
muscles and the mechanical
properties of lung and chest
wall
– Suprasternal Retraction
SSR
– Intercostal Retraction
ICR
– Subcostal Retraction SCR
Suprasternal Retraction SSR
Subcostal Retraction SCR
Intercostal Retraction ICR
• Expiration through partially
closed vocal cords to
increase airway pressure
and lung volume resulting in
improved ventilation-
perfusion (V/P) ratio
• Low pitched expiratory
sound.
Grunting
Evaluation and Investigation
History Examination Investigation
History Examination Investigation
Antenatal US Finding
Amniotic Fluid Index
Renal Agenesis?
Pulmonary Hypoplasia?
Liquor
Oligohydramnio
?Pulmonary
Hypoplasia
Polyhydramnios
?Cong Diaphr
Hernia
?Oesoph
atresia/TEF
MSAF
MAS ? PPHN
Gestation/Delivery
Term LSCS
?TTN
Preterm
?RDS
Postdate
?MAS
History Examination Investigation
Risk Factors
IDM
?Hypoglycaemia
GBS+ve Mother
Sepsis/Congenital
Pneumonia
Condition at birth
Distress
?Met
acidosis
Not vigorous
?Asphyxial Lung
Ds
Require resus at
birth
?Air Leak
Syndrome
Leaking Liquor
>18hrs
?Presumed
Sepsis
PPROM/PROM
Maternal UTI
?Presumed
Sepsis
Term Baby
• TTN
• MAS
• Congenital
Pneumonia
• Dev Anomalies
Preterm Baby
• RDS
• Congenital
Pneumonia
• TTN
at birth
Respiratory
Distress
later after
a period of
normal
function
Possible causes
• Acquired/Nosocomial
Pneumonia
• Dev anomalies
• CHD
• IEM
• Metabolic (Met acidosis/
electrolytes)
• T – hypo/hyperthermic
• RR – tachy/apnoea
• HR – tach/bradycardia
• SPO2 – desaturate?
Vitals
• Pallor
• Plethoric
• SGA/LGA
• Macrosomic/hydroptic
General
Condition
• Cleft palate
• Excessive oral secretion
Oral Cavity
• Pierre Robin
• Potter face
Congenital
anomalies
History Examination Investigation
•Dextrocardi,murmurs
•In-drawing sternum
•Air entry
CVS/Lung
•Scaphoid abdomen
Abdomen
•Meconium stained
Umbilical
cord/
Nails
•Hypotonia
•Poor sucking reflex
•Incomplete Moro
Tone/
Reflexes
Look for:
• O2 Saturation
• Metabolic/ respiratory
acidosis/ alkalosis
• Blood counts
(Hb/TWC/Plt/Ht)
• Glucose level
• Sepsis causative agent
• Collapse/Air Leak/CDH/
Cardiomegaly
DXT Blood
C+S/LP
CXR
Portable
SPO2
monitoring
VBG/ ABG FBC
GENERAL MANAGEMENT
Respiratory
Support
Supportive Care
Definitive/Specific
Therapy
• O2 Delivery
• PEEP/ Mechanical ventilation
(CPAP/SiPAP)
• Intubation and suction
• HR monitoring
• Continuous SPO2
monitoring
• Temp/DXT monitoring
• I/O charting
• Feeding (PO/TPN)
• Cot/Incubator nursing
According to
diagnosis
RDS.pptx

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RDS.pptx

  • 1.
  • 2. • Morning meeting DR IRFAN ALI fcps trainee NURSERY
  • 3. BIODATA • B/O HUMAIRA • DOB : 16th July 2016 • TOB :10 30 AM • DOA : 1st August 2016 • DO L : 16th • GENDER :FEMALE • ADDRESS: SHIKARPUR
  • 4. • c/o Respiratory distress since 1st day of life
  • 5. BIRTH HISTORY • ANTENATAL HISTORY 23 yrs old mother primigravida 38 week of gestation. Booked case. TT received. U/S done
  • 6. Multivitamin taken. No h/o PROM Prolong labour. H/o fever 2 days before c-section.
  • 7. • NATAL HISTORY C-Section at 38 weeks Hospital delivery, • POSTNATAL HISTORY • Cried immediately • No history of resuscitation at birth • First urine and stool passed within 24 hours. • Vitamin k received. • h/o respiratory distress
  • 8. • FAMILY HISTORY 1st issue of non consanguineous marriage. No h/o any significant illness in family. • SOCIOECONOMIC HISTORY Belongs to a poor class family. father is unemployed and lives in house of 2 ventilated rooms
  • 9. Examination • sick looking neonate lying in incubator with visible distress. H/r : 158 b /min R/r : 73 br/min Temp: a/f Oxygen saturations : 95 % at room air J-, A-, Cy- ,D- ,E-
  • 10. Anthropometry Weight 3 kg (50th centile) Length 49 cm (b/w 75th and 50th centile) foc 34 cm (b/w 75th and 50th centile)
  • 11. Systemic examination • Chest : : tachypnea, sternal subcostal and intercostal retractions, nasal flaring, b/l crepts audible.
  • 12. • CVS : S 1 + S 2 + no added sounds CRT 2 Sec • Abdomen : soft NVM present, GS audible • Genitals : female normal genitalia • Anus: patent • SKIN: Normal • Back : Normal
  • 13. • CNS : • Fontanelle open and flat • Moro: • Sucking : • Grasp : fair • Rooting : • Pupils: bilaterally equal and reactive to light.
  • 14. Head to toe examination • Normal with no dysmorphic features.
  • 15. Provisional diagnosis • TERM/ AGA/ NBW • congenital pneumonia • PPHN
  • 16. Management • Admited in nicu • Incubator care • Oxygen support via cpap. • n/g tube passed • NPO till further orders • X-ray chest • echo • Investigations • Maintainance fluids • Iv antibiotics started.
  • 17. Investigations CBC 18-7-16 20-7-16 22-7-16 Hb MCV MCH MCHC 15.5 g/dl 91 fl 32 pg 33 g/dl 14 g/dl 16.2 g/dl WBCs 9,700 15,100 13,000 N 70% (ANC=6790) 77 % (ANC=11,627) 65 % (ANC=8450) L 2O% 15% 28 % M 08% 5 % 05 % E 02% 3 % 02% PLATELETS 163,000 152,000 157,000
  • 18. uce 20-7-16 22-7-16 urea 40 mg/dl 65 mg/dl Cr 0.6 mg/dl 0.8 mg/dl Na 135 mEq/L K 5.12 mEq/L Cl 102 mEq/L
  • 19. • RBS : 100 mg/ dl at the time of presentation serial monitoring remained normal • BBG :B positive Blood c/s; awaited
  • 20. cxr
  • 21. Hospital course • Monitoring of vitals and RBS done • oxygen support continued • Preductal and postductal spo2 was 95%. • Antibiotics changed  Condition gradually improved  Oxygen tapered kept on headbox support • Activity improved • N/G feeding started • Planned to dmf and step down
  • 22. Repeat labs 4-8-16 8-8-16 CBC Hb MVC MCH MCHC 13.5 g/dl 82 fl 26 pg 31 g/dl 13 g/dl 85 fl 25 pg 30 g/dl WBCs 7,500 6,200 N 60 % (ANC=4500) 64 % (ANC=3968) L 36 % 33 % M 02 % 01 % E 02 % O2 % PLATELETS 182,000 2,94,000
  • 23. UCE 04-08-16 08-08-16 Urea 13 26 Cr 0.4 01 Na 140 138 K 5.5 5.6 Cl 101 103
  • 24.
  • 25.
  • 26. FINAL DAIGNOSIS • TERM/ AGA/ NBW • Congenital pneumonia
  • 27.
  • 28. • AN APPROACH TO RESPIRATORY DISTRESS IN NEONATES
  • 29. PLAN • Introduction • Causes and Classification • Respiratory Distress Signs • Evaluation and Investigation • General Management
  • 30. Introduction Respiratory Distress in Newborn = Abnormal respiratory signs in neonates
  • 31.
  • 32. Causes and Classification Respiratory Distress in Newborn Causes Respiratory Extrapulmonary Management Medical Surgical
  • 33. Causes Respiratory Extrapulmonary Upper Airway Obstruction Choanal Atresia Pierre Robin Sequence Laryngeal pathology Lower Airway TTN RDS/HMD MAS Congenital Pneumonia Air Leak Syndrome Milk Aspiration Rib cage anomalies Congenital Diaphragmatic Hernia Neuromuscular diseases PPHN Congenital Heart Diseases Shock Anaemia Polycythaemia Hypoglycaemia Hypothermia Metabolic acidosis Intracranial Birth Trauma/ Encephalopathy
  • 34. Management Medical • TTN • MAS • RDS/HMD • Pneumonia • Milk Aspiration • CHD • Shock • Anaemia • Polycythaemia • Hypoglycaemia • Hypothermia • Metabolic Acidosis Surgical • Choanal atresia • Pierre Robin Sequence • Air Leak Syndrome • Rib cage anomalies • Congenital Diaphragmatic Hernia • Air Leak Syndrome • Intracranial Birth Trauma/ Encephalopathy
  • 35. Respiratory Distress Signs Respiratory Distress in Newborn Tachypnoea Retractions Grunting Nasal Flaring Cyanosis
  • 36. Tachypnoea Respiratory Rate: up to 2 months: 60 or more 2 to 12 months: 50 or more 12 months to 5 years: 40 or more
  • 37. Retractions • Due to negative intrapleural pressure generated between the contraction of diaphragm, respiratory muscles and the mechanical properties of lung and chest wall – Suprasternal Retraction SSR – Intercostal Retraction ICR – Subcostal Retraction SCR
  • 41.
  • 42. • Expiration through partially closed vocal cords to increase airway pressure and lung volume resulting in improved ventilation- perfusion (V/P) ratio • Low pitched expiratory sound. Grunting
  • 43. Evaluation and Investigation History Examination Investigation
  • 44. History Examination Investigation Antenatal US Finding Amniotic Fluid Index Renal Agenesis? Pulmonary Hypoplasia? Liquor Oligohydramnio ?Pulmonary Hypoplasia Polyhydramnios ?Cong Diaphr Hernia ?Oesoph atresia/TEF MSAF MAS ? PPHN Gestation/Delivery Term LSCS ?TTN Preterm ?RDS Postdate ?MAS
  • 45. History Examination Investigation Risk Factors IDM ?Hypoglycaemia GBS+ve Mother Sepsis/Congenital Pneumonia Condition at birth Distress ?Met acidosis Not vigorous ?Asphyxial Lung Ds Require resus at birth ?Air Leak Syndrome Leaking Liquor >18hrs ?Presumed Sepsis PPROM/PROM Maternal UTI ?Presumed Sepsis
  • 46. Term Baby • TTN • MAS • Congenital Pneumonia • Dev Anomalies Preterm Baby • RDS • Congenital Pneumonia • TTN at birth Respiratory Distress later after a period of normal function Possible causes • Acquired/Nosocomial Pneumonia • Dev anomalies • CHD • IEM • Metabolic (Met acidosis/ electrolytes)
  • 47. • T – hypo/hyperthermic • RR – tachy/apnoea • HR – tach/bradycardia • SPO2 – desaturate? Vitals • Pallor • Plethoric • SGA/LGA • Macrosomic/hydroptic General Condition • Cleft palate • Excessive oral secretion Oral Cavity • Pierre Robin • Potter face Congenital anomalies History Examination Investigation
  • 48. •Dextrocardi,murmurs •In-drawing sternum •Air entry CVS/Lung •Scaphoid abdomen Abdomen •Meconium stained Umbilical cord/ Nails •Hypotonia •Poor sucking reflex •Incomplete Moro Tone/ Reflexes
  • 49. Look for: • O2 Saturation • Metabolic/ respiratory acidosis/ alkalosis • Blood counts (Hb/TWC/Plt/Ht) • Glucose level • Sepsis causative agent • Collapse/Air Leak/CDH/ Cardiomegaly DXT Blood C+S/LP CXR Portable SPO2 monitoring VBG/ ABG FBC
  • 50. GENERAL MANAGEMENT Respiratory Support Supportive Care Definitive/Specific Therapy • O2 Delivery • PEEP/ Mechanical ventilation (CPAP/SiPAP) • Intubation and suction • HR monitoring • Continuous SPO2 monitoring • Temp/DXT monitoring • I/O charting • Feeding (PO/TPN) • Cot/Incubator nursing According to diagnosis