Was presented at the Meetings of the Minds State Plan Conference on January 30, 2013.

1. G E O R G E P E R R Y , P H . D .
D E A N A N D P R O F E S S O R
C O L L E G E O F S C I E N C E S
T H E U N I V E R S I T Y O F T E X A S A T S A N A N T O N I O
Alzheimer Disease:
Where Do We Go From Here?

2. Major Focus of Current Basic Research
 Genetics
 Biomarkers
 Amyloid
 Tau
 Oligomerization
 Metabolism
 Lifestyle

3. Continuing Approaches of Basic Research
 Infectious agent
 Environmental toxins
 Inflammation
 Oxidative stress
 Head trauma
 Apolipoprotein E

4. Limitations of Medicine
 Remove the abnormal
OR
 Bring it back to normal function
 This approach has served us well for diseases of defect or from
the outside
 But not for the most important diseases of our time- Alzheimer,
Cancer or metabolic syndrome
 Diseases of the aged are homeostatic and how the body
maintains normal function in the face of decline

5. Recent Developments in Alzheimer Research
 Connection to lifestyle, metabolism and metabolic
syndrome
 Indications of what we can do now to have more
years of healthy living
 Points to how we improve the prognosis of our aging
popluation

6. Progress in Alzheimer Research
 Realization that people with a diagnosis-
 Are human beings capable of giving and receiving love
 Have a life worth living for both themselves and their family