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Causes of Mental Illness
IN THIS ARTICLE
 What Biological Factors Are Involved in Mental Illness?
 What Psychological Factors Contribute to Mental Illness?
 What Environmental Factors Contribute to Mental Illness?
What are the causes of mental illness? Although the exact
cause of most mental illnesses is not known, it is becoming
clear through research that many of these conditions are
caused by a combination of biological, psychological, and
environmental factors.
What Biological Factors Are Involved in Mental
Illness?
Some mental illnesses have been linked to abnormal
functioning of nerve cell circuits or pathways that connect
particular brain regions. Nerve cells within
these brain circuits communicate through chemicals called
neurotransmitters. "Tweaking" these chemicals -- through
medicines, psychotherapy or other medical procedures --
can help brain circuits run more efficiently. In addition,
defects in or injury to certain areas of the brain have also
been linked to some mental conditions.
Other biological factors that may be involved in the
development of mental illness include:
 Genetics (heredity): Mental illnesses sometimes run
in families, suggesting that people who have a family
member with a mental illness may be somewhat more
likely to develop one themselves. Susceptibility is
passed on in families through genes. Experts believe
many mental illnesses are linked to abnormalities in
many genes rather than just one or a few and that
how these genes interact with the environment is
unique for every person (even identical twins). That is
why a person inherits a susceptibility to a mental
illness and doesn't necessarily develop the illness.
Mental illness itself occurs from the interaction of
multiple genes and other factors -- such as stress,
abuse, or a traumatic event -- which can influence, or
trigger, an illness in a person who has an inherited
susceptibility to it.
 Infections: Certain infections have been linked
to brain damage and the development of mental
illness or the worsening of its symptoms. For example,
a condition known as pediatric autoimmune
neuropsychiatric disorder (PANDA) associated with
the Streptococcus bacteria has been linked to the
development of obsessive-compulsive disorder and
other mental illnesses in children.
 Brain defects or injury: Defects in or injury to
certain areas of the brain have also been linked to
some mental illnesses.
 Prenatal damage: Some evidence suggests that a
disruption of early fetal brain development or trauma
that occurs at the time of birth -- for example, loss of
oxygen to the brain -- may be a factor in the
development of certain conditions, such as autism
spectrum disorder.
 Substance abuse : Long-term substance abuse, in
particular, has been linked to anxiety, depression, and
paranoia.
 Other factors: Poor nutrition and exposure to toxins,
such as lead, may play a role in the development of
mental illnesses.
What Psychological Factors Contribute to
Mental Illness?
Psychological factors that may contribute to mental illness
include:
 Severe psychological trauma suffered as a child, such
as emotional, physical, or sexual abuse
 An important early loss, such as the loss of a parent
 Neglect
 Poor ability to relate to others
What Environmental Factors Contribute to
Mental Illness?
Certain stressors can trigger an illness in a person who is
susceptible to mental illness. These stressors include:
 Death or divorce
 A dysfunctional family life
 Feelings of inadequacy, low self-esteem, anxiety,
anger, or loneliness
 Changing jobs or schools
 Social or cultural expectations (For example, a society
that associates beauty with thinness can be a factor in
the development of eating disorders.)
 Substance abuse by the person or the person's
parents
WebMD Medical Reference Reviewed by Smitha Bhandari,
MD on May 20, 2018
Sources
© 2018 WebMD, LLC. All rights reserved

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Causes of mental illness

  • 1. Causes of Mental Illness IN THIS ARTICLE  What Biological Factors Are Involved in Mental Illness?  What Psychological Factors Contribute to Mental Illness?  What Environmental Factors Contribute to Mental Illness? What are the causes of mental illness? Although the exact cause of most mental illnesses is not known, it is becoming clear through research that many of these conditions are caused by a combination of biological, psychological, and environmental factors. What Biological Factors Are Involved in Mental Illness? Some mental illnesses have been linked to abnormal functioning of nerve cell circuits or pathways that connect particular brain regions. Nerve cells within these brain circuits communicate through chemicals called neurotransmitters. "Tweaking" these chemicals -- through medicines, psychotherapy or other medical procedures -- can help brain circuits run more efficiently. In addition, defects in or injury to certain areas of the brain have also been linked to some mental conditions. Other biological factors that may be involved in the development of mental illness include:  Genetics (heredity): Mental illnesses sometimes run in families, suggesting that people who have a family member with a mental illness may be somewhat more likely to develop one themselves. Susceptibility is passed on in families through genes. Experts believe
  • 2. many mental illnesses are linked to abnormalities in many genes rather than just one or a few and that how these genes interact with the environment is unique for every person (even identical twins). That is why a person inherits a susceptibility to a mental illness and doesn't necessarily develop the illness. Mental illness itself occurs from the interaction of multiple genes and other factors -- such as stress, abuse, or a traumatic event -- which can influence, or trigger, an illness in a person who has an inherited susceptibility to it.  Infections: Certain infections have been linked to brain damage and the development of mental illness or the worsening of its symptoms. For example, a condition known as pediatric autoimmune neuropsychiatric disorder (PANDA) associated with the Streptococcus bacteria has been linked to the development of obsessive-compulsive disorder and other mental illnesses in children.  Brain defects or injury: Defects in or injury to certain areas of the brain have also been linked to some mental illnesses.  Prenatal damage: Some evidence suggests that a disruption of early fetal brain development or trauma that occurs at the time of birth -- for example, loss of oxygen to the brain -- may be a factor in the development of certain conditions, such as autism spectrum disorder.  Substance abuse : Long-term substance abuse, in particular, has been linked to anxiety, depression, and paranoia.
  • 3.  Other factors: Poor nutrition and exposure to toxins, such as lead, may play a role in the development of mental illnesses. What Psychological Factors Contribute to Mental Illness? Psychological factors that may contribute to mental illness include:  Severe psychological trauma suffered as a child, such as emotional, physical, or sexual abuse  An important early loss, such as the loss of a parent  Neglect  Poor ability to relate to others What Environmental Factors Contribute to Mental Illness? Certain stressors can trigger an illness in a person who is susceptible to mental illness. These stressors include:  Death or divorce  A dysfunctional family life  Feelings of inadequacy, low self-esteem, anxiety, anger, or loneliness  Changing jobs or schools  Social or cultural expectations (For example, a society that associates beauty with thinness can be a factor in the development of eating disorders.)  Substance abuse by the person or the person's parents WebMD Medical Reference Reviewed by Smitha Bhandari, MD on May 20, 2018
  • 4. Sources © 2018 WebMD, LLC. All rights reserved