INTRODUCTION UN Sustainable development Goals(SDGs); healthy diets, and environment sustainability significant gap in providing sufficient food low-quality diets; micro-nutrient deficiencies and diet-related obesity 60%higher global food requirements by 2050 Domestication of livestock, adaptation of agriculture and the industrial revolution Food alternatives are needed

1. Cellular agriculture-
Industrial biotechnology
for food and materials
Presenters
Raveena Bano – S2018231057
Iqra - S2018231025
Zunaira Nasim - S2018231058
Syed Sibtul Hassan - S2018231019
Department of Life Sciences
University of Management and Technology

2. INTRODUCTION
• UN Sustainable development Goals(SDGs); healthy diets, and environment
sustainability
• significant gap in providing sufficient food
• low-quality diets; micro-nutrient deficiencies and diet-related obesity
• 60%higher global food requirements by 2050
• Domestication of livestock, adaptation of agriculture and the industrial revolution
• Food alternatives are needed
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3. Industrial biotechnology in agriculture
• Key to provide humanity with nutritious, safe and healthy food
• Chemicals and innovative materials
• Minimizing resource input to gain seasonal and geographical
independence.
• Key to provide humanity with nutritious, safe and
healthy food
• Chemicals and innovative materials
• Minimizing resource input to gain seasonal and
geographical independence.
Industrial biotechnology in Agriculture
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4. A-cellular products ; are made of
organic molecules like proteins and
fats and contain no cellular or living
material in the final product
Types of
biotechnol
ogy
Red
Green
White
A-cellular products
Massive yield
increase of crops
through breeding
varieties
A-cellular products
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5. CELLULAR AGRICULTURE
• The production of agriculture
products from cell
cultures (Figure 1)
• Cellular products that are Non-
GM
• A-cellular products in GM org.
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6. Animal cells
Cell-based meat
Clean meat, meat
produced from cells cultures, is
a prominent alternative for
traditional meat, derived from
live animals.
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7. 1
2
3
4
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Inefficiency
• 97% of the calories are lost for
processes regarding body
maintenance.
Environmental problems
• GHG emissions – 10%
• Methane emission - 37%
• Freshwater pollution – 8%
Foodborne illnesses
Overuse of
antibiotics - AMR
strains
Traditional meat
production systems is
not sustainable
Why Clean Meat?
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8. 8

9. 1 2 • Industrial BT of plant
cells – food applications
• < Animal products
• One-third of all
agricultural impact
Maintenance of quality
Plant cells : Environmental Impact
Reduce environmental
footprint
Plant Stem cells
Crop farming for
human consumption
Cosmetic products
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Rare plants
• Exploitation
• No further endangering
• Dedifferentiated cells
• Contain whole cells
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10. Nutritional
recommendations
Digestibility of
crop proteins
Essential amino
acids
Strong Trend
-Substitution
Animal proteins
✔ Plant based alternatives
- Soy, pulses
Crops > Animal
derived proteins
Crop proteins <
Animal proteins
Recent investigations-
nutritional composition
Exhibit differential
digestibility
Efficient absorption
Plant cells
Figure 1.1. The use of
plant cells as food
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11. Production of secondary metabolites
• Anti-cancer drug paclitaxel in 75 000 liter bioreactors
• Ginseng culture exploitation - food supplement
production
Plant cell culture medium
• Fully defined medium
• Less complex and costly comparatively
Plant cells as material constituents
• 3D printing
• Ordered growth
Other benefits of using plant cells
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12. Microbial cells
▪ Microbial cell has been used for food protein production from a long time.
▪ We require downstream processing due to the high concentration of RNA.
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13. Microbes and synthetic materials
▪ Microbes can also be cultivated to make synthetic materials. In nature, macroscopic
materials grown from microbes, such as biofilms, mushrooms, and lichens, have little
relevance as synthetic structural materials.
▪ Microbes can be used to produce various polymers and polymer precursors for materials.
▪ What are emerging field aims?
▪ Challenges?
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14. Fungal Mycelium and Researchers perspective
▪ An interesting material example is fungal mycelium.
▪ Interestingly, for centuries, humans have used fruiting bodies of bracket fungi to make
leather-like textile materials
▪ Presently, designers and workers are reviving this almost forgotten art and are able to
control the mycelium growth into desired materials and shapes.
▪ Aim of company Ecovative Design?
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15. Current opinions in Biotechnology
▪ Headset ‘Korvaa’ demonstrating
the use of microbially produced
materials.
▪ The headset was designed by
Aivan and the materials were
produced by VTT Technical
Research Centre of Finland Ltd
and Aalto University
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16. Other Microbes
▪ Alkalitolerant bacterial cells, such as some Bacillus species, can be cultured to form
biomineralized bricks in a microbially induced calcite precipitation process
▪ Gluconacetobacter can be cultivated to produce very pure cellulose non-woven films
and recently also 3D shapes
▪ Important Note.
▪ Understanding the relevant genetic factors will be highly important for the design of
novel biosynthetic functional materials
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17. THANK YOU!
Any Questions?
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