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Signaling pathway
Different signaling pathways use different mechanisms for signal transduction.
Those mechanisms have different kinds of on/off switches

EGF pathway regulates cell division, and is mutant in many cancers.
Epidermal Growth Factor (EGF) pathway

WT: 1000kDa, larger
Mutant: <1000kDa, smaller

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Lec#4

1. Lecture #4

2. How cell cycle is regulated?

5. Signaling pathway Different signaling pathways use different mechanisms for signal transduction. Those mechanisms have different kinds of on/off switches

6. Competitive inhibitor

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11. EGF pathway regulates cell division, and is mutant in many cancers. Epidermal Growth Factor (EGF) pathway

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13. Dimerize—dimer

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46. DNA is negatively charged

47. WT: 1000kDa, larger Mutant: <1000kDa, smaller

Lec#4

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