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ACUTE APPENDICITIS
Presenter:
Dr. Saad Andalib.
M.B.B.S
Definition:
• Appendicitis is defined as an inflammation of the inner
lining of the vermiform appendix which spreads to its other
parts.
• It results from luminal obstruction followed by infection.
• Calcified fecal matter known as fecolith often plays a role.
Anatomy
• The three taeniae coli converge at the junction of the cecum
and the appendix and can be a useful landmark to identify
the appendix.
• The appendix can vary in length from <1 cm to >30 cm; most
appendices are 6 to 9 cm long.
Variations in topographic position of the
appendix
From its base at the cecum, the appendix may extend (A) upward, retrocecal and
retrocolic; (B) downward, pelvic; (C) downward to the right, subcecal; or (D) upward to
the left, ileocecal (may pass anterior or posterior to the ileum)
Surgical Anatomy – Position:
Etiology:
Obstruction of the lumen is the dominant etiologic factor in
acute appendicitis.
• – Faecolith / faecal stasis
• – Submucosal lymphoid hyperplasia
• – Inspissated barium
• – Vegetable/fruit seeds
• – Worms (Entrobius vermicularis)
• – Tumors of caecum/appendix
Pictorial Explanation
Appendiceal
obstruction/early
appendicitis – visceral
peritoneal irritation
Appendiceal
distension
Irritation of parietal
peritoneum
(localised)
Perforation,
localised/generalised
peritonitis, mass
obstruction
Distention
Distention
causing
Ischemia
Gangrene
Bacteriology:
Common organisms seen in patients with acute
appendicitis
1-Abdominal pain: Classically, pain is initially diffusely centered in the
umbilical area, is moderately to severe in intensity, cramping in nature. After a
period varying from 1 to 12 hours, the pain localizes to the right lower quadrant.
Symptoms:
2-Anorexia: Nearly always accompanies appendicitis. It is so constant that the
diagnosis should be questioned if the patient is not anorectic.
3-Nausia and vomiting: Nausea more common than vomiting. Occurs
in nearly 75% of patients.
4-Obstipation: Begins before the onset of abdominal pain.
-Temperature elevation is rarely > 38.6 °C
-Pulse rate is normal or slightly elevated
-Tenderness often is maximal at or near the McBurney point
-Direct rebound tenderness
-Rovsing sign: pain in the right lower quadrant when palpatory pressure
is exerted in the left lower quadrant
-Psoas sign: indicates an irritative focus in proximity to psoas muscle.
-Obturator: stretching the obturator internus causes irritation of the inflamed
appendix. The test is performed by passive internal rotation of the flexed right thigh
with the patient supine.
Signs:
• Leukocytosis, ranging from 10,000 to 18,000 cells/mm3, usually is
present in patients with acute, uncomplicated appendicitis and often is
accompanied by a moderate polymorphonuclear predominance.
• White blood cell counts are variable. It is unusual for the white blood cell
count to be >18,000 cells/mm3 in uncomplicated appendicitis.
• White blood cell counts above this level raise the possibility of a
perforated appendix with or without an abscess.
• Urinalysis can be useful to rule out urinary tract infection.
Laboratory findings:
USG W/A : Sonographically, the appendix is identified as a blind-ending,
nonperistaltic bowel loop originating from the cecum.
Common signs of acute appendicitis:
A fluid filled non compressible appendix.
Diameter greater than 6mm.
Appendicolith.
Pericecal fluid.
Increased echogenicity.
CT scan: Sensitivity and specificity > 95 %.
Imaging:
Manifestations Value
Symptoms Migration of pain 1
Anorexia 1
Nausea and/or
vomiting
1
Signs Right lower quadrant
tenderness
2
Rebound 1
Elevated temperature 1
Laboratory values Leukocytosis 2
Left shift in leukocyte
count
1
1-ACUTE MESENTERIC ADENITIS
2-Pelvic Inflammatory Disease
3-Ruptured Graafian Follicle
4-Twisted Ovarian Cyst
5-Ruptured Ectopic Pregnancy
6-ACUTE GASTROENTERITIS
7-Meckel's Diverticulitis
8-Crohn's Enteritis
9-Colonic Lesions
Treatment:
Appendectomy :
1- Open appendectomy
2- Laparoscopic appendectomy
Once the decision to operate has been made, the patient should be
prepared for the operating room. Adequate hydration should be
ensured, electrolyte abnormalities should be corrected.
Pre-existing cardiac, pulmonary, and renal conditions should be
addressed.
Administration of antibiotics to all patients with suspected appendicitis.
Open appendectomy:
For open appendectomy most surgeons use either a McBurney (oblique) or
Langer’s incision.
Laparoscopic appendectomy:
• Laparoscopic appendectomy requires the use of three ports.
• The surgeon usually stands to the patient's left. One assistant is
required to operate the camera.
• One trocar is placed in the umbilicus (10 mm).
• Second trocar (5mm) is placed in the suprapubic position. Some
surgeons place this second port in the left lower quadrant.
• Third trocar (5 mm) is variable and usually is either in the left lower
quadrant, epigastrium, or right upper quadrant.
Prognosis:
• The mortality from appendicitis in has steadily decreased
from a rate of 9.9 per 100,000 in 1939 to 0.2 per 100,000 in
recent years.
• Factors responsible are advances in anesthesia, antibiotics, IV
fluids, and blood products.
• Death is usually attributable to uncontrolled sepsis,
peritonitis, intra-abdominal abscesses, or gram-negative
septicemia.
Have a nice day.

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ACUTE APPENDICITIS

  • 2. Definition: • Appendicitis is defined as an inflammation of the inner lining of the vermiform appendix which spreads to its other parts. • It results from luminal obstruction followed by infection. • Calcified fecal matter known as fecolith often plays a role.
  • 3. Anatomy • The three taeniae coli converge at the junction of the cecum and the appendix and can be a useful landmark to identify the appendix. • The appendix can vary in length from <1 cm to >30 cm; most appendices are 6 to 9 cm long.
  • 4. Variations in topographic position of the appendix From its base at the cecum, the appendix may extend (A) upward, retrocecal and retrocolic; (B) downward, pelvic; (C) downward to the right, subcecal; or (D) upward to the left, ileocecal (may pass anterior or posterior to the ileum)
  • 6. Etiology: Obstruction of the lumen is the dominant etiologic factor in acute appendicitis. • – Faecolith / faecal stasis • – Submucosal lymphoid hyperplasia • – Inspissated barium • – Vegetable/fruit seeds • – Worms (Entrobius vermicularis) • – Tumors of caecum/appendix
  • 7. Pictorial Explanation Appendiceal obstruction/early appendicitis – visceral peritoneal irritation Appendiceal distension Irritation of parietal peritoneum (localised) Perforation, localised/generalised peritonitis, mass obstruction Distention Distention causing Ischemia Gangrene
  • 8. Bacteriology: Common organisms seen in patients with acute appendicitis
  • 9. 1-Abdominal pain: Classically, pain is initially diffusely centered in the umbilical area, is moderately to severe in intensity, cramping in nature. After a period varying from 1 to 12 hours, the pain localizes to the right lower quadrant. Symptoms: 2-Anorexia: Nearly always accompanies appendicitis. It is so constant that the diagnosis should be questioned if the patient is not anorectic. 3-Nausia and vomiting: Nausea more common than vomiting. Occurs in nearly 75% of patients. 4-Obstipation: Begins before the onset of abdominal pain.
  • 10. -Temperature elevation is rarely > 38.6 °C -Pulse rate is normal or slightly elevated -Tenderness often is maximal at or near the McBurney point -Direct rebound tenderness -Rovsing sign: pain in the right lower quadrant when palpatory pressure is exerted in the left lower quadrant -Psoas sign: indicates an irritative focus in proximity to psoas muscle. -Obturator: stretching the obturator internus causes irritation of the inflamed appendix. The test is performed by passive internal rotation of the flexed right thigh with the patient supine. Signs:
  • 11. • Leukocytosis, ranging from 10,000 to 18,000 cells/mm3, usually is present in patients with acute, uncomplicated appendicitis and often is accompanied by a moderate polymorphonuclear predominance. • White blood cell counts are variable. It is unusual for the white blood cell count to be >18,000 cells/mm3 in uncomplicated appendicitis. • White blood cell counts above this level raise the possibility of a perforated appendix with or without an abscess. • Urinalysis can be useful to rule out urinary tract infection. Laboratory findings:
  • 12. USG W/A : Sonographically, the appendix is identified as a blind-ending, nonperistaltic bowel loop originating from the cecum. Common signs of acute appendicitis: A fluid filled non compressible appendix. Diameter greater than 6mm. Appendicolith. Pericecal fluid. Increased echogenicity. CT scan: Sensitivity and specificity > 95 %. Imaging:
  • 13. Manifestations Value Symptoms Migration of pain 1 Anorexia 1 Nausea and/or vomiting 1 Signs Right lower quadrant tenderness 2 Rebound 1 Elevated temperature 1 Laboratory values Leukocytosis 2 Left shift in leukocyte count 1
  • 14.
  • 15. 1-ACUTE MESENTERIC ADENITIS 2-Pelvic Inflammatory Disease 3-Ruptured Graafian Follicle 4-Twisted Ovarian Cyst 5-Ruptured Ectopic Pregnancy 6-ACUTE GASTROENTERITIS 7-Meckel's Diverticulitis 8-Crohn's Enteritis 9-Colonic Lesions
  • 16. Treatment: Appendectomy : 1- Open appendectomy 2- Laparoscopic appendectomy Once the decision to operate has been made, the patient should be prepared for the operating room. Adequate hydration should be ensured, electrolyte abnormalities should be corrected. Pre-existing cardiac, pulmonary, and renal conditions should be addressed. Administration of antibiotics to all patients with suspected appendicitis.
  • 17. Open appendectomy: For open appendectomy most surgeons use either a McBurney (oblique) or Langer’s incision.
  • 18. Laparoscopic appendectomy: • Laparoscopic appendectomy requires the use of three ports. • The surgeon usually stands to the patient's left. One assistant is required to operate the camera. • One trocar is placed in the umbilicus (10 mm). • Second trocar (5mm) is placed in the suprapubic position. Some surgeons place this second port in the left lower quadrant. • Third trocar (5 mm) is variable and usually is either in the left lower quadrant, epigastrium, or right upper quadrant.
  • 19.
  • 20. Prognosis: • The mortality from appendicitis in has steadily decreased from a rate of 9.9 per 100,000 in 1939 to 0.2 per 100,000 in recent years. • Factors responsible are advances in anesthesia, antibiotics, IV fluids, and blood products. • Death is usually attributable to uncontrolled sepsis, peritonitis, intra-abdominal abscesses, or gram-negative septicemia.
  • 21. Have a nice day.