This document provides a biography and curriculum vitae for Dragan Nikolic M, Ph.D. It outlines his educational background including a Ph.D. in examination of parameters affecting human adult pancreatic islet insulin secretion capacity. It details his professional experience researching human pancreatic islets and diabetes at various medical institutions in Belgrade, Serbia. It also lists his research skills, interests, memberships, publications, presentations, and computer/language skills.

1. NIKOLIĆ DRAGAN M, Ph.D.
Home Address:Milutina Miljkovica 54v, 11000 Belgrade, Serbia
Home Phone: +381 11 3942 336. Cell phone: +381 64 135 0835
Work: Faculty of Medicine Belgrade, Dr Subotica 9, 11000 Belgrade, University of
Belgrade, Serbia; Clinic for Endocrinology, Diabetes and Metabolic Diseases,
(Laboratory for pancreatic islets culture) Dr Subotica 13, 11000 Belgrade, Clinical Centre
of Serbia Phone: + 381 11 3639 719, Fax: + 381 11 2685 357, E-mail:
dragannikolic8@yahoo.com
EDUCATION:
2010 – Ph.D. degree from Medical Faculty, University of Belgrade, Clinic for
Endocrinology, Diabetes and Metabolic Diseases, (Laboratory for pancreatic islets
culture), Clinical Centre of Serbia, Belgrade
Title of Ph.D. thesis: “Examination of the parameters affecting insulin secretion capacity
of human adult pancreatic islets in culture”
1998 – Master of Science degree of Immunobiology sciences, University of Belgrade,
Faculty of Biology
Title of MSc thesis: “Advantages and disadvantages of RIA and ELISA techniques in
detection of IA (insulin antibodies) and IAA (insulin auto antibodies) in insulin
dependent and non-insulin dependent diabetic patients”
1991 – Bachelor of Science degree, Universitate of Belgrade, Faculty of Biology,
Department of Animal Phisiology
PROFESSIONAL EXPERIENCE:
January 2011 –present Research associate on the project of Serbian Ministry of
Education and Science, No 41002, “Carotid disease in Serbia – pathological dinamics,
prevention, diagnosis and innovative therapeutic procedures, of Academic
Prof.Dr.sc.med. Ph.D. Djordje Radak, Medical Faculty, University of Belgrade.

2. Novembar 2011 –present Research associate, Medical Faculty, University of Belgrade,
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia,
Belgrade.
January 2006 –december 2010 Research assistent on the project „Examination of
factors influencing the number and functional capacity of human fetal and adult islets in
order to achieve the optimal composition of the transplantation graft in Diabetes, type 1“
of Prof.Dr.sc.med. Ph.D. Predrag Djordjević, Medical Faculty, University of Belgrade,
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia,
Belgrade. Group leader on the research in laboratory for human pancreatic islets culture
January 2005- present Research assistant, Medical Faculty, Universitate of Belgrade,
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia,
Belgrade.
Januar 1996-decembar 2005 Research on the project of Serbian Ministry of Education
and Science, „Functional, immunological, metabolic and clinical aspects of
endocrine pancreatic islet transplantation in insulin dependent diabetics, Prof.Dr.sc.med.
Ph.D Predrag Djordjević.. Medical Faculty, University of Belgrade, Clinic for
Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade.
RESEARCH SKILLS:
Determination and standardization of the protocols for isolation of human adult
and fetal pancreatic islets for transplantation in patients with diabetes- type 1
and for experimental studies in vitro.
Obtaining of the pancreatic tissue and transport to the laboratory for cell culture.
Isolation of pancreatic islets from the surrounding exocrine tissue using adequate
Collagenase..
Purification of the islets on Ficol gradient.
Introduction of the isolated islets in the cell culture and estimation of their yield and
viability (by DTZ – staining and glucose –stimulating test).
Determination of apoptosis and necrosis of the islets by FSC and PJ staining.

3. Leadership in researches and project assignments, designing of the experiments in the
laboratory for pancreatic islets culture..
Standardization of ELISA and RIA tests for detection of insulin auto antibodies in newly
discovered diabetic patients.
RESEARCH INTEREST
Diabetes, transplantation, pancreatic islets culture, influence of microorganism on onset
of the diabetes
MEMBERSHIPS:
Member of EASD (European Association for the Study of Diabetes) in 2009 god
Member Organization Commity of Serbian Society for the Study of Diabetes since 2010
Member of Association of University Proffesors, Serbia, since 2012.
Editorial board member of:
Journal of Gastroenterology and Hepatology Research since 2012
American Journal of Current Immunology since 2013
Global Journal of Infectious Diseases and Clinical Research since 2015
Reviewer of American Journal of Biomedical Research
COMPUTER SKILLS:
MS Windows, Word, Excel, Statistica, Sequence Navigator, Power Point, various
Internet and Email systems
LANGUAGE SKILLS:
English , Russian – Basic, Serbian – Native Language
PUBLICATION:
1. Boban Stanojevic, Vladimir Saenko, Lidija Todorovic, Nina Petrovic, Dragan
Nikolic, Vladan Zivaljevic, Ivan Paunovic, Masahiro Nakashima, Shunichi

4. Yamashita, Radan Dzodic. Low VHL mRNA Expression is Associated with More
Aggressive Tumor Features of Papillary Thyroid Carcinoma. PLoS ONE .
12/2014; 9(12):e114511. DOI: 10.1371/journal.pone.0114511.
2. Nikolic DM. Effects of Candida on insulin secretion of human adult pancreatic
islets and possible onset of diabetes. British Journal of Biomedical Science 2014,
71 (2), 73-78.
3. Nikolic DM, Djordjevic PB, Lackovic VB, Stojiljkovic V, Stanojevic B.Effect of
low temperature cultivation on insulin secretory of human pancreatic islets.
Journal of Biological regulators and Homeostatic Agents 2013, Vol 27, no 1:85-
95
4. Stojiljkovic V, Pejic S, Kasapovic J, Gavrilovic Lj, Stojiljkovic S, Nikolic DM,
Snezana B. Glutathione redox cycle in small intestinal mucosa and peripheral
blood of pediatric celiac disease patients. Anais Da Academia Brasileira De
Ciencias 2012, vol. 84, No. 1:175-184.
5. Nikolic Dragan M. Effects of bacterial infection on insulin secretory capacity of
human adult pancreatic islets. British Journal of Biomedical Science 2011, vol.
68, No. 4:181-184.
6. Nikolic Dragan M, Djordjevic PB, Radak Dj, Lackovic V, Bajcetic M, Gostiljac
D et al. Extended time of cold ishemia and its influence on the physiological
function of human adult pancreatic islets. Archives of Biological Sciences 2011,
vol. 63, No. 4:1007-1013.
7. Nikolic Dragan M, P. B. Djordjevic, Vesna Dimitrijevic Sreckovic, I. Paunovic,
Nevena Kalezic, S. Popovic, D Stefanovic and Marina Dzingalasevic: The effect
of different concentrations of liberase hi used in a non automated method for
human adult pancreatis islet isolation. Arch. Biol. Sci; Belgrade, 62 (3), 833-840,
2010.
8. Nikolic, M. D, et al. Comparative Analysis of Collagenase XI and Liberase H1
for the Isolation of Human Pancreatic Islets. Hepato-Gastroenterology 57, 1573-
1578 (2010).
9. Nikolić Dragan M, Djordjevic P, Dimitrijevic-Sreckovic V, Džingalašević M,
Belij S, Kalezić N. Influence of the purification of human adult pancreatic islets
on insulin secretion. Military Medical and Pharmaceutical (VSP) 2010;67:128-
131.
10. Nikolic Dragan, P.B. Djordjevic, V. Dimitrijevic-Sreckovic, N Kalezic, B.
Nikolic. Comparison of insulin secretion between human adult and fetal
pancreatic islets. Transplantationsmedizin, 2010, 22: 176-180.
11. Djordjević Predrag B, Vesna Dimitrijevic-Sreckovic, Vladimir Bumbasirevic,
Radoje Colovic, Dragan Nikolic, Nevenka Raketic, Fadil Canovic. Apoptosis of
human fetal islets during short term culture. Archives of Biological Sciences,
Belgrade, 2009. Vol. 61: 9-15

5. 12. Dimitrijevic Srećković Vesna, Čolak E, Djordjević P, Gostiljac D, Srečkovič B,
Popović S, Canović F, Ilić M, Obrenović R,Vukčevoć V, Nikolić D, Nišić T,
Milić G, Pejčić GP.Prothrombogenic factors and reduced antioxidative defense in
children and adolescents with pre-metabolic and metabolic syndrome. Clinical
Chemistry and laboratory Medicine. 2007, vol 45, br. 9: 1140-1144.
13. .Djordjevic Predrag B, N.M.Lalic, A. Jotic, I. Paunović, K. Lalić, N. Raketić, D.
Nikolić, M. Zamaklar, N. Rajković, Lj. Lukić, V. Dimitrijević-Srećković, M.
Dragašević, D. Nikolić, I. Marković. Human fetal islet (hfi) transplantation (tx) in
type 1 diabetic patients: comaprison of metabolic effects between single and
multiple implantation regimens. Transplantation Preceedings, December, 2004;
vol. 36:9, 2869-73.
14. Djordjevic Predrag B, N. Lalic, V. Bumbasirevic, A. Jotic, I. Paunovic, R.
Colovic, K. Lalic, N. Raketic, D. Nikolic, M. Zamaklar, N. Rajkovic, Lj. Lukic,
14. V. Dimitrijevic-Sreckovic, M. Dragasevic, S. Popovic, D. Gostiljac, F.
Canovic, I. Markovic. Human fetal islet (hfi) transplantation (tx) in type 1
diabetics: comaprison of immunological effects between single and multiple
implantation regimens. Transplantation Preceedings, 2005; 37: 4440-5
CONFERENCE PRESENTATIONS:
Lecture:
1.Dragan Nikolic M. The Influence of Microorganisms (Microbiom) on Insulin Secretion
of Human Pancreatic Islets. New Data on the Etiopathogenesis of Type 2 Diabetes.
WDD 10: Genetic of Metabolic Diseases. BITs 5th
Annual World DNA and Genome Day-
2014, April 25-28 Internattional Conference Center,. Dalian, China. pp 130
2.Dragan M Nikolic. Effects of pancreatic infections on insulin secretion and possible
onset of diabetes. International Conference on Clinical Microbiology and Microbial
Genomics, November 12-14, 2012 Hilton San Antonio Airport, USA. J Microbial
Biochem Technol 2012, vol 4; issue 5: page 39.
3. Dragan Nikolic M. Influence of infection on insulin secretion of pancreatic islets of
human adult, new data on the pathogenesis of diabetes type 2. Congress „Serbian
Diabetes Days 2012“ SASD, Serbian Association for the study of Diabetes, Belgrade, 14-
15 December, 2012, abstract Book, page 29.

6. Oral Presentation:
1. Dragan M Nikolic, Djordjevic PB, Dimitrijevic-Sreckovic V, Popovic S,
Stefanovic D. Povoljnosti i nedostaci procesa purifikacije kao neophodnog koraka
u procesu izolacije ostrvaca humanog adultnog pankreasa. Congress „Serbian
Diabetes Days 2012“ SASD, Serbian Association for the study of Diabetes,
Belgrade, 14-15 December, 2012, abstract Book, page 40.
Miting abstract
1. Nikolić Dragan, Djordjević P, Dimitrijević Srećković V, Paunović I, Kalezić N,
Popović S, Stefanović D. Uticaj bakterijske infekcije na insulinsku sekreciju
ostrvaca humanog adultnog pankreasa. Šesti Srpski kongres o šećernoj bolesti,
Beograd 6-10 decembar 2009, PP 007: str. 48.
2. Djordjević P.,Lalić N., Bumbaširević V.,Paunović I.,Lalić K., Raketić N., Nikolić
D.., Zamaklar M.,Rajković N., Lukić Lj., Dimitrijević Srećković V., Canović F.,
Popović S., Gostiljac D., Marković I.Human fetal transplantation in type 1
diabetics:comparison 0f immunological effects between single and multiple
implantation regimes, 41st EASD Annual Meeting, Athens, 10-15 September
2005, Diabetologia, Vol 48, Supplement l, 2005, A190
3. Dimitrijević-Srećković V.,Čolak E., Djordjević P., Gostiljac D.,Popović S.,
Srećković B., Novaković T., Obrenović R., Canović F., Ilić M., Nikolić D., Milić
G., Nišić T., Panasiuk V., Pejčić G. Reduced antioxidative defense and
prothrombogenic factors in children and adolescents with metabolic syndrome
Abstracts of the 42nd
EASD Annual Meeting, Copenhagen-Malmoe, Denmark-
Sweden, 14-17 September 2006., Diabetologia, Vol 49, Supplement l, 2006, 442
4. Dimitrijević-Srećković V., Djordjević P., Gostiljac D., Čolak E., Srećković B.,
Popović S., Canović F., Ilić M., Nikolić D., Obrenović R., Milić G., Nišić T.,
Pejčić G.Gnjato G.Quinquennial follow-up of prediabetic patients progressing
into diabetic 2nd International Congress on «Prediabetes ant the Metabolic
Syndrome», Barselona, April 25-28, 2007.,Diabetes & Vascular Disease
Research,March 2007, Vol 4, Supplement l, S 105
5. Dimitrijević-Srećković V., Djordjević P., Čolak E., Srećković B., Gostiljac D.,
Popović S., Canović F., Ilić M., Nikolić D., Stojanović J.,Vukosavljević d.,Milić
G.,Nišić T., Pejčić G. Increased values of crp and microalbuminuriaand reduced
total antioxidant status in children and adolescents with metabolic syndrome, 2nd
International Congress on «Prediabetes ant the Metabolic Syndrome», Barselona,
April 25-28, 2007.,Diabetes & Vascular Disease Research,March 2007, Vol 4,
Supplement l, S 212

7. 6. Dimitrijević-Srećković V., Djordjević P., Čolak E., Srećković B., Gostiljac D.,
Popović S., Canović F., Ilić M., Nikolić D.,Stojanović J., Milić G., Nišić T.,
Pejčić., Milošević K.Increased values of c-reactive protein in children and
adolescents with metabolic syndrome 7th Congress of the European
Atherosclerosiss Society, June 10-13, 2007, Helsinki, Atherosclerosis,
Supplements, June 2007,Vol 8, Issue l, 159.
7. Dimitrijević Srećković V.,Čolak E., Djordjević P., Gostiljac D., Novaković T.,
Srećković B., Popović S., Obrenović R.,Canović F.,Ilić M.,Nikolić D.,Nišić
T.,Milić G., Pejčić G. Prothrombogenic factors and reduced antioxidative defense
in children and adolescents with metabolic syndrome Third Santorini Biologie
Prospective Conference 2006,»From Human Genetic Variations to Prediction of
Risks and Responses to Drug and the Environment» Santorini, Greece, Sept 29-
Oct 2, 2006, Abstracts, Poster B4
8. Dimitrijević Srećković V., Djordjević P., Čolak E., Srećković B., Gostiljac D.,
Popović S., Canović F., Ilić M., Nikolić D., Stojanović J., Milić G., Nišić T.,
Pejčić G., Pandrc M. Metabolic syndrome and microalbuminuria in early
glycoregulation disorders, 10th
Meeting of the Medierranean Group for the
study of Diabetes, April 26-29, 2007, Istanbul, Turkey,Abstract Book, 86
9. Dimitrijević Srećković V., Djordjević P., Čolak E., Srećković B., Gostiljac D.,
Popović S., Canović F., Ilić M., Nikolić D., Stojanović J., Nišić T., Pejčić G,
Milošević K. Increased values of c-reactive protein and reduced total
antioxidant status in children and adolescents with metabolic syndrome, 10th
Meeting of the Medierranean Group for the study of Diabetes, April 26-29,
2007, Istanbul, Turkey, Abstract Book, 87
10. Dordjevic P., Dimitrijevic Sreckovic V.,Gostiljac D.,Canovic F.,Raketic N.,
Djukanovic B.,Tasic N.,Slijepcevic D.,Grabez M.,Raca B.,Colak E., Stojanovic J.,
Nikolic D., Popovic S.Assotiation of findrisk (FDR) questionnaire values with the
risk factors for cardiovascular disease (CVD), 11th Meeting of the Mediterranean
Group for the Study of Diabetes, April 23-26, 2009, Malta, Abstract book, 87
11. Dimitrijević Srećković V., Srećković B., Djordjević P., Čivčić M., Stojanovic
J.,Soldatovic I., Nikolic D., Kijanovic Z. Non-alcoholic fat liver diseases may be
sign of pre-metabolic and metabolic syndromes in children, adolescents and
youth, 6th Congress on Prevention of Diabetes and its Complications, April 8-11,
2010, Dresden, Germany, Meet the experts on the Prevention of Diabetes,
www.wcpd2010.com, Abstract CD