(1) Auddalaka, also known as the suicide tree, is a species of tree native to India and parts of southern Asia that grows in coastal areas. (2) All parts of the tree produce a potent poison, especially the milky latex and fruit kernels. Ingestion of even one fruit kernel can be fatal, with signs and symptoms appearing within 1-2 hours and death occurring within 24-48 hours from heart failure. (3) In Ayurveda, auddalaka is used to treat conditions like madness, skin diseases, itching, and arthritis, though it must be processed (shodhana) first when taken internally. The tree has also been used for suicide,

1. AUDDALAKA
AGADA TANTRA
PRESENTATION

2. CONTENTS
Introduction
Basic Data – Latin name, Family, Morphology, varieties,
Active Principles etc.
Mode of Actions
Rasa panchaka –
Indications
Routes of Administration
Fatal dose, Fatal Period
Signs and Symptoms
Recent Research updates
Post Mortem Findings
Medicolegal Importance

3. Auddalaka
BASIC DATA
Latin name:- Cerbera odollam
Family:- Apocynaceae
Vernacular names:-
Kannada :- Chande, Chende
hoo
Hindi:- Dabur, Pilikirbir, Sukan
English:-sea mango

4. Cerbera odollam, the pong-pong tree is a dicotyledonous
angiosperm, a plant species in the family Apocynaceae and
commonly known as the suicide tree, pong-pong, mintolla,
and othalam
Toxic Part:
It bears a fruit known as othalanga that yields a potent poison
that has been used for suicide and murder. All parts of the
tree yield a potent poison, especially the milky latex which
copiously exudes from the stems.

5. Intoduction
KEY WORDS
(1)Auddalaka is a small tree found along coasts
in tropical countries.
(2) It is a species native to India and other parts of
southern Asia, growing preferentially in coastal salt
swamps and in marshy areas but also grown as a
hedge plant between home compounds

6. Varities:- cerebra odollum
Cerebra thevatia
ACTIVE PRINCIPALS:-
Cerberin
Cerberoside
Odollum
Odollotoxin
Thevetin
Cerapain

7. MODE OF ACTION
Cerberin has a mechanism of action similar to digoxin;
hence, Cerbera odollam toxicity manifests similar to
acute digoxin poisoning. Ingestion of its kernel causes
nausea, vomiting, hyperkalemia, thrombocytopenia,
and ECG abnormalities. Exposure to high doses of
Cerbera odollam carries the highest risk of mortality.

8. 01 Add your title
Add your text here. Add your text here.
Text
Rasa
s
Gun
a
Virya
Vipaka
Katu
Tikta
Ushna
Laghu
Ruksha
Please add a
comment here.
Katu
Vata
Shamaka
RASA PANCHAKA

9. Leaves
Flower

10. Fruit with seed

11. Useful parts:
bark,latex,leaves,fruits
Bark
Fruit

12. INDICATIONS:-
Pacifies vitiated
vata and kapha
Unmada
Kusta
Kandu
Pakshagata
Arthritis
Aasthma
Nephritis
Medyaa( improve intellect)
Purgative and emetics.
Route of administration:-
External (as paste)
Internal (after shodhana)
FATAL DOSE:- kernel of one fruit.
FETAL PERIOD:-24 to 48 hrs
SIGNS AND SYMPTOMS:
They appear within one or 2 hrs in the GIT
initially.there is bitter taste, nausea, vomiting.
Abdominal pain, severe retching.Diarrhea,
genaral weakness.Blurring of vision,sinus
bradycardia.Irregular respiration,
collapse.Death from heart failure.

13. POSTMORTEM FINDINGS:-
Congested eyes
Congested internal organs
Congested and edematous lung
Subepicardial subendocardial and
subpleural petechial hemorrhage
Stomach mucous congested with
hemorrhages and gastritis
The findings find in same as
asphyxia.
MEDICO-LEGAL
IMPORTANCE:-
Common method in
(i)Suicide &
(2)Homicide (Cerberin is difficult
to detect in autopsies)
As a part of ritual-trial of ordeal.

14. Research
The in vitro anti-cancer activities of 17βH-neriifolin isolated from
Cerbera odollam and its binding activity on Na+, K+-ATPase
Phytochemical analysis, antioxidant assay and antimicrobial activity in
leaf extracts of Cerbera odollam Gaertn
Abinash Sahoo, Thankamani Marar
Pharmacognosy Journal 10 (2), 2018
Potential of Cerbera odollam as a bio-fungicide for post-
harvest pathogen Penicilium digitatum Harbant Singh, Sue
Yin-Chu, Ghassan Al-Samarrai, Muhammad Syarhabil AIP
Conference Proceedings.

15. REFERENCES:-
Text book:-shekar numburii,text book of agada tantra, vegitable
poisons,chokambha publications,2020-21,pg -111-113.
Dr.k.s.narayan reddy,the synopsis of forensic medicine and toxicology,
cardiac poisons,pg-307,
Dr. prakash L hegde,dr.harini, dravya Guna vignana,KARAVEERA, chokambha
publications new delhi.
Dr shobha Bhat .k, A text book of Agadatantra, Audalaka,Karaveera,
choukambha orientalia
Easy ayurveda,Nerium indicum – Karavira – Benefits, Usage, Side Effects –
Ayurveda details,(online),( cited 2013 oct 14). Available from:
https://www-easyayurveda-
com.cdn.ampproject.org/v/s/www.easyayurveda.com/2013/10/14/nerium-
indicum-karavira-benefits-usage-side-effects-ayurveda-
details/?amp_js_v=a6&amp_gsa=1&usqp=mq331AQKKAFQArABIIACAw%3
D%3D#aoh=16393727512816&csi=1&referrer=https%3A%2F%2Fwww.goog

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