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You have to dream
before your dreams can
come true.
A.P.J.Abdul Kalam
SINGLE DIGIT IMR IN KERALA :
Dream or Reality
-Dr.Arjun.B (Final Year)
Contents
• IMR – What & Why ?
• Numbers : Past & Present
– India story
– Kerala story
• Kerala – Cause analysis
• Making dreams come true – how ?
• Conclusion
Infant Mortality Rate
• “Ratio of infant deaths registered in a given year to the total
number of live births registered in the same year;
• usually expressed as a rate per 1000 live births
• STRICTLY SPEAKING – NOT A ‘RATE’,
Infant Mortality Rate =
Deaths among Children <1 year
Number of live births
x1000
BUT A ‘RATIO’
Health Indicators
INFANT MORTALITY RATE
IMR – more than just deaths
• Proxy indicator of population health
• Reflect the socio-economic development of a country
• Sensitive indicator of perinatal care
• Sensitive indicator of the availability, utilization and
effectiveness of health care service and medical technology
Why focus on infant deaths
• Largest single age-category of mortality
• Deaths are due to a particular set of diseases & conditions;
different from adults
• Effect of health programmes on infant mortality is quick
compared to general death rate
• Affected by
– Biological
– Economic
– Social
Numbers : Past & Present
Global IMR trend
Source : United Nations Population Division's World Population Prospects
• 1965 – 114.8
2015 – 31.7
Year
IMR
GLOBAL
• 8.1% of all deaths
• 75 % of Under-5 deaths
• 4,500,000 Infant Deaths in 2015
Source : UN Inter-agency Group for Child Mortality Estimates
IMR – 31.7 / 1000 live births
12,329 Infants die every Hour
• HIGHEST – Angola (96)
• LOWEST (2)
– Japan
– Norway
– Singapore
– Sweden
– Finland
IMR trend in India
Source : United Nations Population Division's World Population Prospects / SRS 2014
• 1965 – 153
2015 – 38
Year
IMR
13 % of all Deaths,
as against 8.1% at global level.
HIGHEST – MP (52)
LOWEST :
•Goa
•Manipur
•Kerala
SRS 2014 – 39 (R – 43; U – 26)
(10)
(11)
(12)
Source : SRS
INFANT Deaths – A closer look
0 - 7 8 - 28 29 - 365
SRS 2014
Neonatal
Mortality Rate
(NMR)
Early Late
Post-Neonatal Mortality
Rate
365 days
12
5 1
6
6
Trend of Child Mortality Rates in India
SRS 2000 - 2012
Kerala – Setting Targets !
• 2/3 reduction by 2020 and, 50% reduction by 2030
• 2/3 reduction of
– IMR from 12 to 8 by 2020 and 6 by 2030,
– NMR from 7 to 5 by 2020, 3 by 2030,
– <5MR from 14 to 9 by 2020 and 7 by 2030
Target 3.2: By 2030 end preventable deaths of newborn and
children under-5 years (NMR<12 & U5MR to 25/1000 livebirths)
What are the infants dying of ?
Source : IAP report on ‘Why infants continue to die in the state of Kerala?”
[1]
[2]
[3]
≤28 days 75%
>28 days 25%
Source : *CBHI Health Profile 2015, *Census India report on Causes of death 2010-2013
Making Dreams come True – How ?
When the nation goes right,
we go left !
• Interventions need to be catered for the state
• Eg.
– ITN for prematurity, (No endemic malaria)
– JSY to improve Institutional delivery, (Kerala 99.9%)
*CES- 2009
1.Prematurity
• 90% of preterm babies in LIC die within the first few days;
• Less than 10% in high-income settings.
• Causes :
– 45–50% are idiopathic.
– Multiple pregnancies
– Infections
– Chronic conditions, such as diabetes and high blood
pressure;
– Maternal factors (Young or advanced maternal age, short
inter-pregnancy intervals and low maternal BMI)
How many child deaths can we prevent this year. Child Survival Series. The Lancet.2003;362.
Interventions Reduction in NMR
Full antenatal care 10–20%
Detection and treatment of
asymptomatic bacteriuria
Incidence of prematurity or
low birth weight: 20–55%
Antenatal corticosteroids for
preterm labour
25 – 50%
Extra care for LBW infants: extra
warmth,
20 – 40%
Emergency neonatal care:
management of serious illness
15-50%
Evidence-based, cost-effective interventions: how many newborn babies can we save? Lancet Neonatal Survival series 2005
HUMAN MILK BANK
Bharadva K, Tiwari S, Mishra S, Mukhopadhyay K, Yadav B, Agarwal RK, Kumar V. Human milk banking guidelines. Indian
pediatrics. 2014 Jun 1;51(6):469-74.
2.Congenital anomalies
Interventions
• Primary prevention :
– Periconceptional Folate
– Availability of genetic services for couples with a family
history
• Secondary prevention :
– prenatal screening and diagnosis
– followed by the offer of termination of pregnancies
affected by major anomalies
Czeizel, A. E. (2005). Birth Defects Are Preventable. International Journal of Medical Sciences, 2(3), 91–92.
3.Sepsis and 4.Birth asphyxia
• Despite the fact that all deliveries are at hospitals (99.9%)
– Neonatal sepsis contributed to around 12% of infant
deaths.
• Despite a very high LSCS rate (43%),
– deaths are still happening due to birth asphyxias.
Infant Death audit to review current care against
standard of care
Dream or Reality ?Dream or Reality !
TOTAL RURAL URBAN
Total Male Female Total Male Female Total Male Female
12 10 13 14 12 15 10 8 11
Conclusion
1. So far, So good.
2. Why are the infants dying ? – Data gap
3. Focus on the neonates
4. Public health  Clinical
5. Strengthen facilities
References
1. Park’s Textbook of Preventive and Social medicine , 23rd
Edition
2. United Nations Inter-agency Group for Child Mortality Estimation. 2015. Levels & Trends in Child Mortality. Report 2015.
[http://childmortality.org/]. New York
3. World Health Organization, 2015, Health in 2015: From MDGs Millennium Development Goals to SDGs Sustainable
Development Goals, Geneva. [www .who.int/gho/publications/mdgs-sdgs/]
4. You D, Hug L, Ejdemyr S, Idele P, Hogan D, Mathers C, Gerland P, New JR, Alkema L. Global, regional, and national levels and
trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the
UN Inter-agency Group for Child Mortality Estimation. The Lancet. 2015 Dec 11;386(10010):2275-86.
5. SRS 2011, 2012, 2013, 2014
6. Census 2011
7. An Analysis of Levels and Trends in Infant and Child Mortality Rates in India, National Institute of Public Cooperation and
Child Development
8. UN Inter-agency Group for Child Mortality Estimates
9. IAP report on ‘Why infants continue to die in the state of Kerala?”
10. How many child deaths can we prevent this year. Child Survival Series. The Lancet.2003;362
11. CBHI Health Profile 2015
12. Census India report on Causes of death 2010-2013
13. Evidence-based, cost-effective interventions: how many newborn babies can we save? Lancet Neonatal Survival series
2005
14. Bharadva K, Tiwari S, Mishra S, Mukhopadhyay K, Yadav B, Agarwal RK, Kumar V. Human milk banking guidelines. Indian
pediatrics. 2014 Jun 1;51(6):469-74.
15. Czeizel, A. E. (2005). Birth Defects Are Preventable. International Journal of Medical Sciences, 2(3), 91–92.
THANK
YOU !

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Single digit IMR (Infant Mortality Rate) in Kerala : Dream or Reality ?

  • 1.
  • 2. You have to dream before your dreams can come true. A.P.J.Abdul Kalam
  • 3. SINGLE DIGIT IMR IN KERALA : Dream or Reality -Dr.Arjun.B (Final Year)
  • 4. Contents • IMR – What & Why ? • Numbers : Past & Present – India story – Kerala story • Kerala – Cause analysis • Making dreams come true – how ? • Conclusion
  • 5. Infant Mortality Rate • “Ratio of infant deaths registered in a given year to the total number of live births registered in the same year; • usually expressed as a rate per 1000 live births • STRICTLY SPEAKING – NOT A ‘RATE’, Infant Mortality Rate = Deaths among Children <1 year Number of live births x1000 BUT A ‘RATIO’
  • 7. IMR – more than just deaths • Proxy indicator of population health • Reflect the socio-economic development of a country • Sensitive indicator of perinatal care • Sensitive indicator of the availability, utilization and effectiveness of health care service and medical technology
  • 8. Why focus on infant deaths • Largest single age-category of mortality • Deaths are due to a particular set of diseases & conditions; different from adults • Effect of health programmes on infant mortality is quick compared to general death rate • Affected by – Biological – Economic – Social
  • 9. Numbers : Past & Present
  • 10.
  • 11. Global IMR trend Source : United Nations Population Division's World Population Prospects • 1965 – 114.8 2015 – 31.7 Year IMR
  • 12. GLOBAL • 8.1% of all deaths • 75 % of Under-5 deaths • 4,500,000 Infant Deaths in 2015 Source : UN Inter-agency Group for Child Mortality Estimates IMR – 31.7 / 1000 live births 12,329 Infants die every Hour
  • 13. • HIGHEST – Angola (96) • LOWEST (2) – Japan – Norway – Singapore – Sweden – Finland
  • 14.
  • 15. IMR trend in India Source : United Nations Population Division's World Population Prospects / SRS 2014 • 1965 – 153 2015 – 38 Year IMR 13 % of all Deaths, as against 8.1% at global level. HIGHEST – MP (52) LOWEST : •Goa •Manipur •Kerala SRS 2014 – 39 (R – 43; U – 26) (10) (11) (12)
  • 16.
  • 18. INFANT Deaths – A closer look 0 - 7 8 - 28 29 - 365 SRS 2014 Neonatal Mortality Rate (NMR) Early Late Post-Neonatal Mortality Rate 365 days 12 5 1 6 6
  • 19. Trend of Child Mortality Rates in India SRS 2000 - 2012
  • 20. Kerala – Setting Targets ! • 2/3 reduction by 2020 and, 50% reduction by 2030 • 2/3 reduction of – IMR from 12 to 8 by 2020 and 6 by 2030, – NMR from 7 to 5 by 2020, 3 by 2030, – <5MR from 14 to 9 by 2020 and 7 by 2030 Target 3.2: By 2030 end preventable deaths of newborn and children under-5 years (NMR<12 & U5MR to 25/1000 livebirths)
  • 21. What are the infants dying of ? Source : IAP report on ‘Why infants continue to die in the state of Kerala?” [1] [2] [3] ≤28 days 75% >28 days 25%
  • 22.
  • 23. Source : *CBHI Health Profile 2015, *Census India report on Causes of death 2010-2013
  • 24. Making Dreams come True – How ?
  • 25. When the nation goes right, we go left ! • Interventions need to be catered for the state • Eg. – ITN for prematurity, (No endemic malaria) – JSY to improve Institutional delivery, (Kerala 99.9%) *CES- 2009
  • 26. 1.Prematurity • 90% of preterm babies in LIC die within the first few days; • Less than 10% in high-income settings. • Causes : – 45–50% are idiopathic. – Multiple pregnancies – Infections – Chronic conditions, such as diabetes and high blood pressure; – Maternal factors (Young or advanced maternal age, short inter-pregnancy intervals and low maternal BMI) How many child deaths can we prevent this year. Child Survival Series. The Lancet.2003;362.
  • 27. Interventions Reduction in NMR Full antenatal care 10–20% Detection and treatment of asymptomatic bacteriuria Incidence of prematurity or low birth weight: 20–55% Antenatal corticosteroids for preterm labour 25 – 50% Extra care for LBW infants: extra warmth, 20 – 40% Emergency neonatal care: management of serious illness 15-50% Evidence-based, cost-effective interventions: how many newborn babies can we save? Lancet Neonatal Survival series 2005
  • 28. HUMAN MILK BANK Bharadva K, Tiwari S, Mishra S, Mukhopadhyay K, Yadav B, Agarwal RK, Kumar V. Human milk banking guidelines. Indian pediatrics. 2014 Jun 1;51(6):469-74.
  • 30. Interventions • Primary prevention : – Periconceptional Folate – Availability of genetic services for couples with a family history • Secondary prevention : – prenatal screening and diagnosis – followed by the offer of termination of pregnancies affected by major anomalies Czeizel, A. E. (2005). Birth Defects Are Preventable. International Journal of Medical Sciences, 2(3), 91–92.
  • 31. 3.Sepsis and 4.Birth asphyxia • Despite the fact that all deliveries are at hospitals (99.9%) – Neonatal sepsis contributed to around 12% of infant deaths. • Despite a very high LSCS rate (43%), – deaths are still happening due to birth asphyxias. Infant Death audit to review current care against standard of care
  • 32. Dream or Reality ?Dream or Reality !
  • 33. TOTAL RURAL URBAN Total Male Female Total Male Female Total Male Female 12 10 13 14 12 15 10 8 11
  • 34. Conclusion 1. So far, So good. 2. Why are the infants dying ? – Data gap 3. Focus on the neonates 4. Public health  Clinical 5. Strengthen facilities
  • 35. References 1. Park’s Textbook of Preventive and Social medicine , 23rd Edition 2. United Nations Inter-agency Group for Child Mortality Estimation. 2015. Levels & Trends in Child Mortality. Report 2015. [http://childmortality.org/]. New York 3. World Health Organization, 2015, Health in 2015: From MDGs Millennium Development Goals to SDGs Sustainable Development Goals, Geneva. [www .who.int/gho/publications/mdgs-sdgs/] 4. You D, Hug L, Ejdemyr S, Idele P, Hogan D, Mathers C, Gerland P, New JR, Alkema L. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for Child Mortality Estimation. The Lancet. 2015 Dec 11;386(10010):2275-86. 5. SRS 2011, 2012, 2013, 2014 6. Census 2011 7. An Analysis of Levels and Trends in Infant and Child Mortality Rates in India, National Institute of Public Cooperation and Child Development 8. UN Inter-agency Group for Child Mortality Estimates 9. IAP report on ‘Why infants continue to die in the state of Kerala?” 10. How many child deaths can we prevent this year. Child Survival Series. The Lancet.2003;362 11. CBHI Health Profile 2015 12. Census India report on Causes of death 2010-2013 13. Evidence-based, cost-effective interventions: how many newborn babies can we save? Lancet Neonatal Survival series 2005 14. Bharadva K, Tiwari S, Mishra S, Mukhopadhyay K, Yadav B, Agarwal RK, Kumar V. Human milk banking guidelines. Indian pediatrics. 2014 Jun 1;51(6):469-74. 15. Czeizel, A. E. (2005). Birth Defects Are Preventable. International Journal of Medical Sciences, 2(3), 91–92.

Editor's Notes

  1. nfant mortality is a proxy indicator of population health. There is a potential association between the causes of infant mortality and factors that are likely to influence health status of the whole population. (IMR) is one those core population health indicators as it reveals the quality of life of mothers and other family members, the access to and quality of health services, access to a good nutrition, education, human rights and security, inequity in deprived population groups and the environment.
  2. Preventable newborn deaths account for 44 percent of all deaths among children under the age of fi ve globally. Th is fi gure is even higher for India. Four out of fi ve newborn deaths result from three treatable conditions: Complications during childbirth (including birth asphyxia), newborn infections, and complications from prematurity. It has been estimated that preventable neonatal deaths can be decreased by at least 50% through implementation and scale-up of educational interventions that include neonatal resuscitation and other essential elements of basic newborn care.
  3. Given the high rate of preterm births in the country and level of malnutrition that ensues in the postnatal growth in such babies after birth, there is an urgent need to establish milk banks across the country, especially in the large neonatal units of all hospitals. The first milk bank in Asia under the name of Sneha, founded by Dr. Armeda Fernandez, was started in Dharavi, Mumbai on November 27, 1989. Currently, the number of human milk banks (HMB) has grown to nearly 14 all over India BF within 1 hr – 68 % Kerala – 78.8 % (DLHS 2012-13) Mysore – 76 % (Dakshayani et al) INDIA – 33.5% (NFHS) EBF for 6 months – 45 % Kerala – 56.2 % (NFHS 3 ) Orissa – 47.5% (Chakrabarty et al) Globally – 36 %
  4. The current rate of C-sections in government hospitals in the State is 43 per cent, which is unacceptably high. Table 3. Cause specific effect of interventions to reduce sepsis and birth asphyxia deaths8 Interventions Reduction in neonatal deaths due to sepsis Reduction in birth asphyxia deaths Skilled maternal and immediate neonatal care 10-20% 30-45% Emergency obstetric care: management of complications—obstructed labour, haemorrhage, hypertension, infections - 20-60% Case management for pneumonia 20-55% - Emergency neonatal care 30-70% -
  5. Dream bigger and aim at zero preventable deaths