This document provides information on the Clinical and Molecular Immunology module. The module aims to provide an integrated understanding of the human immune system in health and disease at the molecular and cellular level. It will cover topics such as the cellular components of the immune system, generation of T-cell and B-cell diversity, inflammation, antibodies, immune responses to microorganisms, clinical immunology, transplantation, and immunological techniques. Students will learn through lectures, practical classes, and independent study. The module assessment includes a lab practical, classroom tests, written assignments, and a final exam.

1. ICIS Module Spec - BI3S74 Clinical and Molecular Immunology
Saved on: Thursday 06 November 2014 09:05PM
BI3S74 - Clinical and Molecular Immunology 09 MAY 2012 - 30 SEP 2018 | Version 1
Associated Module Information
Module Code: BI3S74
Module Title: Clinical and Molecular Immunology
Faculty: Faculty of Health, Sport and Science
Faculty Group: Department of Science and Sport
Faculty Sub Group: N/A
Module Leader: Martin B Powell
Module Team: Stuart I Hogg
First Intended Intake: NOV 2012 Final Year of Intake: NOV 2012
Date Validated: 27 NOV 2012 Date Closed: N/A
Credit Value: 20 Credit Level: 6 (Honours (H))
Language: English
Percentage of Module Taught in Welsh: 0
Equivalent Module: N/A
JACS Code:
ASC Code:
Document Version Information
Version: 1
Valid From: 09 MAY 2012
Valid To: 30 SEP 2018
Module Aims
To provide an up to date and integrated understanding of the human immune system in health and disease at
the molecular and cellular level
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2. Content Summary
Cellular components of the immune system (e.g. T- & B-cells, granulocytes, dendritic cells, platelets) and
lymphoid tissues (bone marrow and thymus). Generation of T-cell and B-cell receptor diversity Inflammation,
antibodies, major histocompatibility complex, antigen presentation, cytokines, cell-mediated immunity, immune
regulation and immune tolerance
121
Immunity to microorganisms (bacteria, viruses, parasites) Clinical immunology: Hypersensitivity and allergy.
Autoimmunity using inflammatory bowel disease as an example. Transplantation
Immunological techniques: antibodies in research and diagnosis; including immunohistochemistry, ELISA,
FACS analysis.
Learning and Teaching Methods
Activity Type Hours
Lecture 48
Practical classes and workshops 10
Independent Study 142
Total Hours Selected 200
Learning Outcomes
# Learning Outcome
1 Understand the different arms of the immune response (innate and cell-mediated), their initiation, response
and regulation.
2 Understand how the immune system protects an organism from infection by micro-organisms and how
inadequate or inappropriate responses result in disease pathology.
3 Understand the role of the immune system in common immunological pathologies (e.g autoimmune disease)
and how the immune system can be manipulated in clinical therapy.
4 Have acquired a knowledge and understanding of the laboratory techniques associated with this academic
discipline.
ICIS Module Spec - BI3S74 Clinical and Molecular Immunology
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3. ICIS Module Spec - BI3S74 Clinical and Molecular Immunology
Module Requisites
Pre / Co Requisites
Module Code Module Title Requisite Type
BI2S64 Medical Microbiology Pre-Requisite
Other Requisites
Other Prerequisite(s):
N/A
Other Corequisite(s):
N/A
Assessment Criteria
Assessment
Assessment Description Duration Word
Category
Count
Weight
(%)
Best
of?
Practical Lab practical 1 2 sessions each of
three 2 hour classes
720 N/A 20 No
Set Exercise -
Time
Constrained
Classroom test -
Time
constrained 1
Between 6-8
classroom tests with
5-10 questions per
test.
15 N/A 10 No
Written
Assignment
Exercise 1 2 assignments
based on current
research papers
240 500 10 No
Written Exam Written exam -
closed book
(unseen) 1
Final examination at
the end of the
module
180 N/A 60 No
Assessment Matrix
Learning Outcomes
Assessment Criteria 1 2 3 4
Written exam - closed book (unseen) 1 Yes Yes Yes -
Classroom test - Time constrained 1 Yes Yes Yes -
Lab practical 1 - - - Yes
Exercise 1 Yes Yes Yes -
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4. ICIS Module Spec - BI3S74 Clinical and Molecular Immunology
Reading List
# Reading List Entry
1 Male D, Rostoff J & Roitt IM (2006) Immunology 7th ed (Mosby)
2 Janeway CA, Travers P, Walport M & Schlomchik MJ (2005) Immunobiology 6th ed (Churchill Livingstone)
3 122
4 Abbas AK, Lichtman AH and Pillai S (2011) Cellular and Molecular Immunology. 7th Edition. (Saunders)
5 Where possible the most current version of reading materials will be used during the delivery of this module.
Comprehensive reading lists are provided to students in their handbooks and via the Blackboard Learning
environment. Reading Lists will be updated annually.
Key Skills
# Key Skill
1 1. Intellectual skills
2 2. Communication skills
3 3. Organisational skills
4 4. Interpersonal/teamwork skill
5 5. Research Skills
6 6. Numeracy Skills
7 7. Computing and IT skills
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