Non-alcoholic fatty liver disease (NAFLD) is associated with insulin resistance and an increased risk of cardiovascular and liver damage. It is diagnosed through identification of risk factors including obesity, diabetes, and hyperlipidemia. The disease is linked to mechanisms like insulin resistance affecting lipid metabolism and inflammatory pathways, which can also impact the risk of heart disease and vascular damage over time.

1. ‫ﺑﻣﻘﺎوﻣﺔ‬ ‫ﺻﻠﺗﮫ‬ ‫(و‬NAFLD) ‫ﻟﻛﺣلو‬ ‫ﻓﻲا‬ ‫ط‬‫ا‬‫ر‬ ‫ﻹﻓ‬ ‫ا‬‫ن‬ ‫ﻋ‬ ‫ﻟﻧﺎﺟم‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫ﻧﻲ‬ ‫ھ‬‫د‬ ‫ﻟ‬ ‫ا‬‫د‬ ‫ﻟﻛﺑ‬ ‫ا‬‫ض‬‫ر‬ ‫ﻣ‬ ‫ﻟﻘﻠب‬ ‫ا‬‫ض‬‫ا‬‫ر‬ ‫ﻣ‬ ‫أ‬‫و‬،‫ن‬ ‫ﯾﯾ‬ ‫ا‬‫ر‬ ‫ﻟﺷ‬ ‫ا‬‫ب‬ ‫ﺗﺻﻠ‬ ‫و‬، ( ‫م‬‫د‬ ‫ﻟ‬ ‫ا‬‫ت‬ ‫ﺷﺣﻣﯾﺎ‬ ‫ﻋﺳر‬ ‫ي‬‫أ‬ )
‫ﺳﻠﯾﺑﯾدﻣﯾﺎ‬ ‫د‬‫و‬،‫ن‬ ‫ﻷﻧﺳوﻟﯾ‬ ‫اﻟﺗﺎﺟﯾﺔا‬
‫ﻣﻠﺧص‬ ‫ﻟﯾس‬ ‫ﻟﻛن‬ ‫ﻟﻛﺑدﯾﺔو‬ ‫ا‬‫نوھد‬ ‫ﻟ‬ ‫ا‬‫م‬ ‫ﺗارﻛ‬ ‫ﯾق‬ ‫رط‬‫ن‬ ‫ﻋ‬ ‫ﻟﻛﺣلو‬ ‫ﻓﻲا‬ ‫ﻹﻓطار‬ ‫ا‬‫ن‬ ‫ﻋ‬ ‫ﻟﻧﺎﺟﻣﺔ‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫ﻟھدﻧﯾﺔ‬ ‫ا‬
‫ﻟﻛﺑد‬ ‫ا‬‫ضار‬ ‫ﻣ‬ ‫أ‬‫ص‬ ‫ﺗﺷﺧﯾ‬ ‫ﯾﺗم‬ ‫ﻓﻲ‬ ‫ﻹﻓطار‬ ‫ا‬‫ن‬ ‫ﻋ‬ ‫ﻟﻧﺎﺟم‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫ﻟھدﻧﻲ‬ ‫ا‬‫د‬ ‫ﻟﻛﺑ‬ ‫ا‬‫ضر‬ ‫ﻣ‬ ‫نأ‬‫ت‬ ‫ﻟاردﺳﺎ‬ ‫ا‬‫ن‬ ‫ﻣ‬ ‫ﻟﻌدﯾد‬ ‫ا‬‫تر‬ ‫ﮭ‬ ‫ظأ‬‫د‬ ‫ﻗ‬ ‫ﻟﻛﺣلو.و‬ ‫ﺗﻌﺎطﻲا‬ ‫ﺑﺳﺑب‬
‫ﻓﻲ‬ ‫ﻟﻸﻧﺳوﻟﯾن‬ ‫ﻟنوھد‬ ‫ا‬‫ر‬ ‫ﻟﺗﻛﺳﯾ‬ ‫ﻣﺿﺎد‬ ‫ﺗﺄﺛﯾر‬ ‫ﻓﻲ‬ ‫ﻣﻘﺎوﻣﺔ‬ ‫ﻟﻰ‬ ‫إ‬‫يدؤ‬ ‫ﯾ‬ ‫ﻣﻣﺎ‬ ‫ﻷﻧﺳوﻟﯾن‬ ‫ﺑﻣﻘﺎوﻣﺔا‬ ‫ﻣرﺗﺑط‬ (NAFLD) ‫ﻟﻛﺣلو‬ ‫ﻟﻰا‬ ‫(إ‬FFAs) ‫ﻟﺣةر‬ ‫ﻟھدﻧﯾﺔا‬ ‫ا‬‫ض‬ ‫ﻷﺣﻣﺎ‬ ‫ا‬‫ةد‬ ‫ﯾﺎ‬ ‫ز‬‫يدؤ‬ ‫ﺗ‬ ‫(.و‬FFAs) ‫ﻟﺣةر‬ ‫ﻟھدﻧﯾﺔا‬ ‫ا‬
‫ﻷﺣﻣﺎض‬ ‫ا‬‫ةد‬ ‫ﯾﺎ‬ ‫ﻣﻊز‬ ‫ﻟھدﻧﯾﺔ‬ ‫ﻷﻧﺳﺟﺔا‬ ‫ا‬‫د‬ ‫ﻟﻛﺑ‬ ‫ا‬‫ضر‬ ‫ﺑﻣ‬ ‫ﻟﻣﺻﺎﺑﯾن‬ ‫ا‬‫ص‬ ‫ﻷﺷﺧﺎ‬ ‫ا‬‫ت‬ ‫ﺣﺎﻻ‬ ‫ﻓﻔﻲ‬ ،‫ك‬ ‫ﻟ‬ ‫ﻋﻠﻰذ‬ ‫ﻋﻼةو‬ ‫ﻟﺷﺣﻣﯾﺔ.و‬ ‫ﻟﺳﻣﯾﺔا‬ ‫ا‬‫روط‬ ‫ﺗ‬ ‫و‬‫يرد‬ ‫ﻣﺗﻘ‬ ‫ﯾﻔﻲ‬ ‫ظو‬‫ل‬ ‫ﺧﻠ‬ ‫ﻟﻘﻠب‬ ‫ا‬‫نوھد‬‫م‬ ‫ﺗﺗارﻛ‬ ‫ﻛﻣﺎ‬ ‫ﯾﺿﺎ‬ ‫أ‬‫ةذ‬ ‫ﻟﻣﻧﺗﺑ‬ ‫ا‬‫نوھد‬ ‫ﻟ‬ ‫ا‬
‫ﺗﺗارﻛم‬ ،(NAFLD) ‫ﻟﻛﺣلو‬ ‫ﻓﻲا‬ ‫ﻹﻓطار‬ ‫ا‬‫ن‬ ‫ﻋ‬ ‫ﻟﻧﺎﺟم‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫اﻟھدﻧﻲ‬
‫ﻓﻲ‬ ‫ﻹﻓطار‬ ‫ا‬‫ن‬ ‫ﻋ‬ ‫ﻟﻧﺎﺟم‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫ﻟھدﻧﻲ‬ ‫ا‬‫د‬ ‫ﻟﻛﺑ‬ ‫ا‬‫ضر‬ ‫ﻣ‬ ‫ﺗرﺑط‬ ‫ﻟﺗﻲ‬ ‫ا‬‫ت‬ ‫ﻵﻟﯾﺎ‬ ‫ا‬‫ل‬ ‫ﺑﺗﺣﻠﯾ‬ ‫ﻗﻣﻧﺎ‬ ‫ﻻﺳﺗﻌضار‬ ‫ا‬‫اذھ‬ ‫ﻓﻲ‬ ‫ﻟﺑﻧﻛرﯾﺎس.و‬ ‫او‬‫ضار‬ ‫ﻣ‬ ‫أ‬‫مد‬ ‫ﺗﻘ‬ ‫و‬‫روط‬ ‫ﺑﺗ‬ ‫ﺗﺑﺎطﮫ‬ ‫ﻟمد(راو‬ ‫ا‬‫ت‬ ‫ﺷﺣﻣﯾﺎ‬ ‫)ﻋﺳر‬ ‫ﺳﻠﯾﺑﯾدﻣﯾﺎ‬ ‫ﻟﻐاذﺋﻲدو‬ ‫ا‬‫ل‬ ‫ﻟﺗﻣﺛﯾ‬ ‫ا‬
‫ﺑﻣﺗﻼزﻣﺔ‬ (NAFLD) ‫اﻟﻛﺣلو‬
.‫ﻟدﻣوﯾﺔ‬ ‫ﻷوﻋﯾﺔا‬ ‫او‬‫ب‬ ‫اﻟﻘﻠ‬
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‫ﺗرﺟﻣﺔاذھ‬ ‫ﺟرﯾت‬ ‫أ‬‫د‬ ‫ﻗ‬ ‫و‬.‫ﻹﻧﺟﻠﯾزﯾﺔ‬ ‫ا‬‫ر‬ ‫ﻏﯾ‬ ‫ﻟطﺑﯾﺔ‬ ‫ا‬‫ثو‬ ‫ﻟﺑﺣ‬ ‫ا‬‫ت‬ ‫ﻟﻣﻘﺎﻻ‬ ‫ﻟﻌﺎﻟﻣﯾﺔ‬ ‫ﻟؤرﯾﺔا‬ ‫ا‬‫م‬ ‫ﻟﻔﮭ‬ ‫ﺗﺟرﺑﺔ‬ ‫ُﺟير‬ ‫ﻧ‬ ،‫ﻟطﺑﯾﺔ‬ ‫ا‬‫ت‬ ‫ﻟﻣﻛﺗﺑﺎ‬ ‫ا‬‫ء‬ ‫ﻣﻧﺎ‬ ‫أ‬‫ن‬ ‫ﻧﺣ‬ ‫ﻧﺎ‬ ‫ﻟﻠﺟﻣﯾﻊھ‬ ‫ﻟﻣﺗﺎح‬ ‫ا‬‫ل‬ ‫ﻟﻣﻘﺎ‬ ‫ﻟﻰا‬ ‫إ‬‫ط‬ ‫ﺑ‬ ‫ارو‬PubMed ‫ﺑﺑﻣد‬ ‫ﻗﺗﺑﺎس‬ ‫ﻋﻠﻰا‬
‫ﻹطﻼع‬ ‫ا‬‫ن‬ ‫ﯾﻣﻛ‬ ‫و‬.‫ﻣﻌﺗﻣد‬ ‫ﻣﺗرﺟم‬ ‫ﺑاوﺳطﺔ‬ ‫اﻟﻣﻠﺧص‬
‫ﻟﻣﺷعور‬ ‫ﻋﻠﻰا‬ ‫ﺗﻌﻠﯾﻘﺎﺗك‬ ‫ﺿﺎﻓﺔ‬ ‫ﻓﻲإ‬ ‫ﺗﺗددر‬ ‫ﻻ‬ .https://www.ncbi.nlm.nih.gov/pubmed/?term=23666091
.‫ﻷﺻﻠﯾﺔ‬ ‫ﻟﻠﻐﺔا‬ ‫ا‬‫نو‬ ‫ﯾﺗﻛﻠﻣ‬ ‫ﻣن‬ُ ‫ﻣ‬ُ
‫ﻛﻧت‬ ‫ﻟﺗرﺟﻣﺔاذإ‬ ‫ا‬‫ةدو‬ ‫ﺟ‬ ‫ﻋﻠﻰ‬ ‫و‬،‫ه‬ ‫دأﻧﺎ‬
. ‫و‬‫د‬‫ا‬‫ر‬‫و‬ ‫ﻛوﻟ‬ ‫ﺟﺎﻣﻌﺔ‬ ،‫ﺻﺣﯾﺔ‬‫ﻟ‬ ‫ا‬‫م‬‫و‬ ‫ﻟﻌﻠ‬ ‫ﻣﻛﺗﺑﺔا‬ ،‫ﺑﻲ‬ ‫ﻧﺎآ‬ ‫ا‬‫د‬‫و‬‫ر‬ ‫ﻓﻛ‬ ‫و‬‫ھ‬‫ن‬ ‫--ﻟﯾﻠﯾﺎ‬

2. Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary
heart disease
Abstract
Non-alcoholic fatty liver disease is marked by hepatic fat accumulation not due to alcohol abuse. Several studies have demonstrated that
NAFLD is associated with insulin resistance leading to a resistance in the antilipolytic effect of insulin in the adipose tissue with an increase of
free fatty acids (FFAs). The increase of FFAs induces mitochondrial dysfunction and development of lipotoxicity. Moreover, in subjects with
NAFLD, ectopic fat also accumulates as cardiac and pancreatic fat. In this review we analyzed the mechanisms that relate NAFLD with
metabolic syndrome and dyslipidemia and its association with the development and progression of cardiovascular disease.
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We are medical librarians conducting an experiment to understand the global visibility of non-English medical research articles. The
translation for this abstract was performed by a certified translator. The PubMed citation and link to the whole open access article can be
found here https://www.ncbi.nlm.nih.gov/pubmed/?term=23666091. Please feel free to add your comments below on the project and, if you are
a native-speaker, on the quality of the translation.
--Lilian Hoffecker and Dana Abbey, Health Sciences Library, University of Colorado.