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MACROMOLECULAR
ANALYSIS
Mentor :
Dr. Nidhi Tiwari mam
Presented By:
Utkarsh Mishra
Branch : CSE (Core)
Sec. : ‘D’
Sem. : 4th
Roll No. : 19
Why are Macromolecules important to the
Human Body?
Macromolecules are essential to the
functioning of the human body.
Carbohydrates are the body’s main source of energy.
Lipids provide stored energy reserves. This allows us to
survive when carbohydrates are not being supplied to the body.
Protein helps us stay strong, by forming new bones and
muscles, and helping us fight diseases.
Nucleic acids are responsible for making each person
functional and unique; they are the blueprint for our genetic
structure.
Objectives
Learn Basic Structure and Function of:
• Carbohydrates
• Lipids
• Protein
• Nucleic Acids
…And Learn The Role of Enzyme Catalysts!
Carbohydrates are formed of carbon,
hydrogen, and oxygen atoms with a ratio of
1:2:1.
The two categories of carbohydrates include
sugar and starch.
Carbohydrates Are the main energy
source of the body!
Glucose is an
example of a
simple sugar.
The smallest unit of saccharides is a monosaccharide.
(“Mono” = one)
Examples: Glucose & Fructose
Monosaccharides combine together to form disaccharides
(“Di” = two)
Examples: Lactose & Sucrose
Carbohydrates are composed of
saccharides
Monosaccharides are also referred to
as Simple Sugars
Oligosaccharides are chains of 3-10 Monosaccharides.
(“Oligo” = few)
Polysaccharides are the largest unit of carbohydrates
(“Poly” = many)
Starches are polysaccharide chains made from
300 - 1000 glucose units.
Monosaccharides can also form larger
carbohydrates such as:
Polysaccharides
are referred to as
complex
carbohydrates.
 Enzymes in the mouth, stomach, and small
intestine, breakdown the carbohydrate
molecules.
 These large complex carbohydrate molecules
breakdown into simple sugars.
Carbohydrate Breakdown
Simple Sugar
Structure
How Does The Breakdown Occur?
Our bodies use special protein molecules called
enzymes to break the larger molecules into smaller
pieces.
Enzymes Are Catalysts
[Catalysts are chemicals that quicken a chemical reaction without
undergoing any change themselves]
• Activation Energy is the energy needed to start a reaction.
• Enzymes are protein catalyst that speeds up biological
reactions by lowering the activation energy. Enzymes help
naturally occurring slow life processes to speed up.
The Role of Enzymes
Each enzyme is very specific and only attaches to one
type of molecule.
The molecule the enzyme acts upon is called its substrate.
The Role of Enzymes
Variables that impact enzyme activity :
• Temperature
• pH
Protein
Proteins are nutrients which contain materials the body uses
for growth and repair.
Proteins are made of Carbon, Hydrogen, Oxygen and
Nitrogen.
Proteins are large molecules made up of combinations of
amino acids.
Amino Acid
Structure
• Amino acids are the building blocks of proteins.
• These building blocks bond together to form chains that
are called peptides.
• Proteins are formed of combinations of large peptides
chains, this is referred to as polypeptides.
Amino Acids Peptides Polypeptides Protein
In order for the body to use protein,
enzymes in the stomach and small intestine
break the polypeptides down into individual
amino acids.
Lipids
Lipids function as stored energy, insulation for the
body, and assist absorption of certain vitamins.
Lipids are large molecules that can be categorized as
fats or oils.
Lipids are composed of triglycerides.
These molecules are made up of carbon, hydrogen, and
oxygen atoms.
Glycerol + 3 Fatty Acids  Triglyceride
Chain of Triglycerides  Lipid
Triglycerides
Bile and enzymes in the small intestine
break lipids down into small molecules of
fatty acids and glycerol.
Lipid Breakdown
Nucleic Acids
DeoxyriboNucleic Acid (aka DNA)
Is a Nucleic Acid.
 Stores and Carries Genetic Information.
Composed of Nucleotides.
 Unlike the other macromolecules, nucleic acids
are not obtained from food.
Nucleotides are made of three
parts:
1. A five-carbon sugar
2. A base that has nitrogen (N)
atoms
3. An ion of phosphoric acid known
as phosphate (PO43-)
All nucleic acids are made from combinations of nucleotides.
There are five nucleotides:
uracil, cytosine, thymine, adenine, and guanine
Nucleotides
Thank You
Sources :
Wikipedia
Google
Book of ‘Principles of Biochemistry’

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Macromolecules Presentation.pptx

  • 1. MACROMOLECULAR ANALYSIS Mentor : Dr. Nidhi Tiwari mam Presented By: Utkarsh Mishra Branch : CSE (Core) Sec. : ‘D’ Sem. : 4th Roll No. : 19
  • 2. Why are Macromolecules important to the Human Body? Macromolecules are essential to the functioning of the human body. Carbohydrates are the body’s main source of energy. Lipids provide stored energy reserves. This allows us to survive when carbohydrates are not being supplied to the body. Protein helps us stay strong, by forming new bones and muscles, and helping us fight diseases. Nucleic acids are responsible for making each person functional and unique; they are the blueprint for our genetic structure.
  • 3. Objectives Learn Basic Structure and Function of: • Carbohydrates • Lipids • Protein • Nucleic Acids …And Learn The Role of Enzyme Catalysts!
  • 4. Carbohydrates are formed of carbon, hydrogen, and oxygen atoms with a ratio of 1:2:1. The two categories of carbohydrates include sugar and starch. Carbohydrates Are the main energy source of the body! Glucose is an example of a simple sugar.
  • 5. The smallest unit of saccharides is a monosaccharide. (“Mono” = one) Examples: Glucose & Fructose Monosaccharides combine together to form disaccharides (“Di” = two) Examples: Lactose & Sucrose Carbohydrates are composed of saccharides Monosaccharides are also referred to as Simple Sugars
  • 6. Oligosaccharides are chains of 3-10 Monosaccharides. (“Oligo” = few) Polysaccharides are the largest unit of carbohydrates (“Poly” = many) Starches are polysaccharide chains made from 300 - 1000 glucose units. Monosaccharides can also form larger carbohydrates such as: Polysaccharides are referred to as complex carbohydrates.
  • 7.  Enzymes in the mouth, stomach, and small intestine, breakdown the carbohydrate molecules.  These large complex carbohydrate molecules breakdown into simple sugars. Carbohydrate Breakdown Simple Sugar Structure
  • 8. How Does The Breakdown Occur? Our bodies use special protein molecules called enzymes to break the larger molecules into smaller pieces. Enzymes Are Catalysts [Catalysts are chemicals that quicken a chemical reaction without undergoing any change themselves]
  • 9. • Activation Energy is the energy needed to start a reaction. • Enzymes are protein catalyst that speeds up biological reactions by lowering the activation energy. Enzymes help naturally occurring slow life processes to speed up. The Role of Enzymes
  • 10. Each enzyme is very specific and only attaches to one type of molecule. The molecule the enzyme acts upon is called its substrate. The Role of Enzymes Variables that impact enzyme activity : • Temperature • pH
  • 11. Protein Proteins are nutrients which contain materials the body uses for growth and repair. Proteins are made of Carbon, Hydrogen, Oxygen and Nitrogen. Proteins are large molecules made up of combinations of amino acids. Amino Acid Structure
  • 12. • Amino acids are the building blocks of proteins. • These building blocks bond together to form chains that are called peptides. • Proteins are formed of combinations of large peptides chains, this is referred to as polypeptides. Amino Acids Peptides Polypeptides Protein
  • 13. In order for the body to use protein, enzymes in the stomach and small intestine break the polypeptides down into individual amino acids.
  • 14. Lipids Lipids function as stored energy, insulation for the body, and assist absorption of certain vitamins. Lipids are large molecules that can be categorized as fats or oils. Lipids are composed of triglycerides. These molecules are made up of carbon, hydrogen, and oxygen atoms.
  • 15. Glycerol + 3 Fatty Acids  Triglyceride Chain of Triglycerides  Lipid Triglycerides
  • 16. Bile and enzymes in the small intestine break lipids down into small molecules of fatty acids and glycerol. Lipid Breakdown
  • 17. Nucleic Acids DeoxyriboNucleic Acid (aka DNA) Is a Nucleic Acid.  Stores and Carries Genetic Information. Composed of Nucleotides.  Unlike the other macromolecules, nucleic acids are not obtained from food.
  • 18. Nucleotides are made of three parts: 1. A five-carbon sugar 2. A base that has nitrogen (N) atoms 3. An ion of phosphoric acid known as phosphate (PO43-) All nucleic acids are made from combinations of nucleotides. There are five nucleotides: uracil, cytosine, thymine, adenine, and guanine Nucleotides
  • 19. Thank You Sources : Wikipedia Google Book of ‘Principles of Biochemistry’

Editor's Notes

  1. Image Credit: http://www.bbc.co.uk/bitesize/ks3/science/images/protein_molecules.gif
  2. http://i1-news.softpedia-static.com/images/news2/What-Do-We-Really-Know-about-Fats-Are-All-Fats-Bad-2.bmp
  3. http://www.bodyrecomposition.com/wp-content/uploads/2009/05/triglyceride.gif
  4. Image Credit: http://www.bbc.co.uk/bitesize/ks3/science/images/fat_molecules.gif
  5. http://images.sciencedaily.com/2011/07/110721142408-large.jpg