2. Magnesium
“Magnesium is a cofactor in more then 300
enzymes systems that regulate diverse
biochemical reactions in the body, including
protein synthesis, muscle and nerve function,
blood glucose control, and blood pressure
regulations.”-NIH
3. Magnesium
Required for synthesis of DNA, RNA, and
Antioxidant Glutathione.
Active Transport of Calcium and potassium ions
across cell membranes.
An adult body contains approximately 25g of
magnesium
Magnesium homeostasis is largely controlled by
the kidneys.
5. Sources of Magnesium
Green leafy vegetables, such as
spinach, Legumes, nuts, seeds and
whole grains.
30-40% of the dietary magnesium
consumed is absorbed by the body.
Supplements such as magnesium
citrate, oxide, and chloride
6. Groups at Risk for Magnesium
Inadequacy
People with Gastrointestinal
disease.
People with type 2 diabetes.
People with alcohol dependence
Older adults
7. Magnesium and health
“Habitually low intakes of magnesium induce
changes in biochemical pathways that can
increase the risk of illness over time”- NIH
Hypertension and cardiovascular disease
Type 2 diabetes
Osteoporosis
Migraines
Antioxidant Glutathione. Recycles antioxidants “ the mother of all antioxidants (www.huffingtonpost.com/dr-mark-hyman)
DNA Deoxyribonucleic Acid. This holds biological instructions that make each of us unique. (www.gnome.gov)
RNA Ribonucleic Acid. Polymeric molecule made up of one or more nucleotide.
RDA Recommended Daily Allowance
It has been noted that magnesium in aspartate, citrate, lactate, and chloride forms is absorbed more completely then magnesium oxide and magnesium sulfate
Gastrointestinal disease the reduced absorption from the gut or the increased loss from the body. (National Institution of health)
Type 2 diabetes The magnesium loss appears to be secondary to higher concentration of glucose in the kidneys that increase urine output.(NIH)
Alcohol dependence Poor dietary intake and nutrition status.(NIH)
Older adults They have lower dietary intake the young adults.(NIH)
Hypertension and cardiovascular disease studies have shown that magnesium supplementation lowers blood pressure.(NIH)
Type 2 diabetes Diets higher in in magnesium are associated with lower risks of diabetes. (NIH)
Osteoporosis Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts.
Migraines. Magnesium deficiency is related to factors that promote headaches, including neurotransmitter release and vasoconstriction.
Bisphosphonates magnesium- rich supplements can decrease the absorption of oral bisphonates. (NIH)
Antibiotics Magnesium can form insoluble complexes with tetracycline's. (NIH)
Diuretics these can increase the loss of magnesium in the urine and lead to magnesium depletion
Proton Pump InhibitorsFDA advises healthcare professionals to consider measuring patients serum magnesium levels prior to initiating long-tempt treatment to check magnesium levels periodically in patients. (NIH)
