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BioMed Central
Page 1 of 2
(page number not for citation purposes)
Molecular Cancer
Open AccessEditorial
Frequently asked questions about Molecular Cancer
Karsta Lüttich1, Christian Schmidt*2,3 and Guido M Sclabas3
Address: 1Department of Dermatology, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York, 10021, USA,
2Editor-in-Chief, Molecular Cancer, BioMed Central Ltd, Middlesex House, 34–42 Cleveland Street, London W1T 4LB, UK and 3Department of
Surgical Oncology and Molecular Oncology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas
77030, USA
Email: Karsta Lüttich - kal2003@mail.med.cornell.edu; Christian Schmidt* - christian.schmidt@molecular-cancer.org;
Guido M Sclabas - guido.m.sclabas@molecular-cancer.org
* Corresponding author
Abstract
Molecular Cancer is as a forum for cutting edge cancer-related papers. This editorial will answer
frequently asked question about this open-access and on-line journal as well as its publisher BioMed
Central.
Editorial
There is no question that immediate and unrestricted ac-
cess to information stimulates scientific communication.
The Freedom of Information Act "provides individuals
with a right to access to records in the possession of the
federal government" http://www.nih.gov/icd/od/foia/.
Indeed, almost every research funding comes from indi-
viduals and/or governmental institutions, and I firmly be-
lieve it is the right of everyone to access any kind of
scientific information without barriers and free of charge.
There is no limitation to positive data, because many
"prominent medical journals often provide insufficient
information to assess the validity of studies with negative
results" [1] to allow a rigorous evaluation of the quality of
these results. A newly launched journal focuses on "well
documented results/conclusions that are unexpected,
controversial, provocative and/or negative in the context
of current tenets" [2]. Molecular Cancer and its publisher
BioMed Central are fully devoted to open access publish-
ing and there is no doubt that this will be the golden
standard for scientific publishing [3–10].
Molecular Cancer is embedded in a family of related on-
line journals, all with BioMed Central's open-access poli-
cy. Molecular Cancer focuses on all areas of cancer-related
science, from bench and bedside [11] and publishes im-
mediately after accepting; this concept is paying us back
[12–19]. We, the editors of Molecular Cancer, are willing
to make the journal even more attractive and are not
afraid of work and effort. We do not charge extra for color-
ed pictures, amount of data presented in the paper and/or
supplemental data and so on.
Everything produces costs [8]; who will pay for it [20,21]?
BioMed Central charges a flat fee of $500 after a paper is
being accepted for publication. In return, the authors re-
tain their copyright and the paper is freely accessible with-
out barriers and fees to everyone. Again, visibility and
access rates are higher. There are no costs for an unlimited
number of papers if the submitting author's Institution is
a member of BioMed Central http://www.biomedcen-
tral.com/inst/. Next, a number of funding agencies explic-
itly allow direct use of their grants to covering the article
processing charges:
• Canadian Institutes of Health Research http://www.cihr-
irsc.gc.ca/
• Deutsche Forschungsgemeinschaft http://www.dfg.de/
Published: 31 January 2003
Molecular Cancer 2003, 2:16
Received: 9 January 2003
Accepted: 31 January 2003
This article is available from: http://www.molecular-cancer.com/content/2/1/16
© 2003 Lüttich et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the article's original URL.
Publish with BioMed Central and every
scientist can read your work free of charge
"BioMed Central will be the most significant development for
disseminating the results of biomedical research in our lifetime."
Sir Paul Nurse, Cancer Research UK
Your research papers will be:
available free of charge to the entire biomedical community
peer reviewed and publishedimmediately upon acceptance
cited in PubMed and archived on PubMed Central
yours — you keep the copyright
Submit your manuscript here:
http://www.biomedcentral.com/info/publishing_adv.asp
BioMedcentral
Molecular Cancer 2003, 2 http://www.molecular-cancer.com/content/2/1/16
Page 2 of 2
(page number not for citation purposes)
• Fonds zur Förderung der wissenschaftlichen Forschung
http://www.fwf.ac.at/
• Health Research Board http://www.hrb.ie/
• Howard Hughes Medical Institute http://www.hh-
mi.org/
• International Human Frontier Science Program Organi-
zation http://www.hfsp.org/
• Israel Science Foundation http://www.isf.org.il/
• National Health Service http://www.doh.gov.uk/
• National Institutes of Health http://www.nih.gov/
• National Science Foundation http://www.nsf.gov/
• Rockefeller Foundation http://www.rockfound.org/
• Swiss National Science Foundation http://www.snf.ch/
There is further assistance in publication costs. The Soros
Foundation http://www.soros.org/ allows authors from
certain countries to apply for help in getting manuscripts
published.
Conclusion
Molecular Cancer is an open-access and on-line journal;
its publisher fulfills the Freedom of Information Act and
guarantees access to papers without barriers and fees. Mo-
lecular Cancer does not charge for colored pictures,
amount of data presented in the paper and/or supplemen-
tal data, page charges etc. BioMed Central charges a flat fee
of $500 after a paper is being accepted for publication; in
return, the authors retain their copyright. A number of
funding agencies explicitly allow direct use of their grants
to cover article processing charges; there are no costs for
an unlimited number of accepted papers if the submit-
ting author's Institution is a member of BioMed Central.
Authors' contributions
CS drafted the paper, and KL and GS provided suggestions
and comments to the paper. All authors read and ap-
proved the final manuscript.
References
1. Hebert RS, Wright SM, Dittus RS and Elasy TA Prominent medical
journals often provide insufficient information to assess the
validity of studies with negative results. J Negat Results Biomed
2002, 1:1
2. Pfeffer C and Olsen BR Editorial: Journal of Negative Results in
Biomedicine. J Negat Results Biomed 2002, 1:2
3. Verma IM Censorship of scientific publications: a bad idea. Mol
Ther 2002, 5:337
4. Trayhurn P The public library of science and "open access" to
the scientific literature. Br J Nutr 2002, 87:1-2
5. Suber P Open access to the scientific journal literature. J Biol
2002, 1:3
6. Delamothe T "Author pays" may be the new science publish-
ing model BMJ 2003, 326:182
7. Smith R The market for medical journals is anticompetitive,
says expert BMJ 2003, 326:182
8. Eaton L "Free" medical publishing venture gets under way.
BMJ 2003, 326:11
9. Nenadic G, Mima H, Spasic II, Ananiadou S and Tsujii J Terminology-
driven literature mining and knowledge acquisition in bio-
medicine. Int J Med Inf 2002, 67:33-48
10. Grivell L Mining the bibliome: searching for a needle in a hay-
stack? New computing tools are needed to effectively scan
the growing amount of scientific literature for useful infor-
mation. EMBO Rep 2002, 3:200-203
11. Schmidt C Bench and Bedside. Mol Cancer 2002, 1:1
12. Lynch C, Tycko B, Bestor T and Walsh C Reactivation of a si-
lenced H19 gene in human rhabdomyosarcoma by demeth-
ylation of DNA but not by histone hyperacetylation. Mol
Cancer 2002, 1:2
13. Arias-Pulido H, Narayan G, Vargas H, Mansukhani M and Murty VV
Mapping common deleted regions on 5p15 in cervical carci-
noma and their occurrence in precancerous lesions. Mol Can-
cer 2002, 1:3
14. Ohnishi K, Ota I, Yane K, Takahashi A, Yuki K, Emoto M, Hosoi H and
Ohnishi T Glycerol as a chemical chaperone enhances radia-
tion-induced apoptosis in anaplastic thyroid carcinoma cells.
Mol Cancer 2002, 1:4
15. Gao X, Loggie B and Nawaz Z The roles of sex steroid receptor
coregulators in cancer. Mol Cancer 2002, 1:7
16. Zhang P, Gao W, Turner S and Ducatman BS Gleevec (STI-571) in-
hibits lung cancer cell growth (A549) and potentiates the cis-
platin effect in vitro. Mol Cancer 2003, 2:1
17. Moore PS, Beghelli S, Zamboni G and Scarpa A Genetic abnormal-
ities in pancreatic cancer. Mol Cancer 2003, 2:7
18. Juhasz M, Nitsche B, Malfertheiner P and Ebert MP Implications of
growth factor alterations in the treatment of pancreatic can-
cer. Mol Cancer 2003, 2:5
19. Carew JS and Huang P Mitochondrial defects in cancer. Mol Can-
cer 2002, 1:9
20. Wheatley D and Grynszpan D Can we speed up the online pub-
lishing process? And who will pay for it, anyway? Cancer Cell Int
2002, 2:5
21. Velterop J Author charges are the future. BMC News and Views
2001, 2:2

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1476-4598-2-16

  • 1. BioMed Central Page 1 of 2 (page number not for citation purposes) Molecular Cancer Open AccessEditorial Frequently asked questions about Molecular Cancer Karsta Lüttich1, Christian Schmidt*2,3 and Guido M Sclabas3 Address: 1Department of Dermatology, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York, 10021, USA, 2Editor-in-Chief, Molecular Cancer, BioMed Central Ltd, Middlesex House, 34–42 Cleveland Street, London W1T 4LB, UK and 3Department of Surgical Oncology and Molecular Oncology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA Email: Karsta Lüttich - kal2003@mail.med.cornell.edu; Christian Schmidt* - christian.schmidt@molecular-cancer.org; Guido M Sclabas - guido.m.sclabas@molecular-cancer.org * Corresponding author Abstract Molecular Cancer is as a forum for cutting edge cancer-related papers. This editorial will answer frequently asked question about this open-access and on-line journal as well as its publisher BioMed Central. Editorial There is no question that immediate and unrestricted ac- cess to information stimulates scientific communication. The Freedom of Information Act "provides individuals with a right to access to records in the possession of the federal government" http://www.nih.gov/icd/od/foia/. Indeed, almost every research funding comes from indi- viduals and/or governmental institutions, and I firmly be- lieve it is the right of everyone to access any kind of scientific information without barriers and free of charge. There is no limitation to positive data, because many "prominent medical journals often provide insufficient information to assess the validity of studies with negative results" [1] to allow a rigorous evaluation of the quality of these results. A newly launched journal focuses on "well documented results/conclusions that are unexpected, controversial, provocative and/or negative in the context of current tenets" [2]. Molecular Cancer and its publisher BioMed Central are fully devoted to open access publish- ing and there is no doubt that this will be the golden standard for scientific publishing [3–10]. Molecular Cancer is embedded in a family of related on- line journals, all with BioMed Central's open-access poli- cy. Molecular Cancer focuses on all areas of cancer-related science, from bench and bedside [11] and publishes im- mediately after accepting; this concept is paying us back [12–19]. We, the editors of Molecular Cancer, are willing to make the journal even more attractive and are not afraid of work and effort. We do not charge extra for color- ed pictures, amount of data presented in the paper and/or supplemental data and so on. Everything produces costs [8]; who will pay for it [20,21]? BioMed Central charges a flat fee of $500 after a paper is being accepted for publication. In return, the authors re- tain their copyright and the paper is freely accessible with- out barriers and fees to everyone. Again, visibility and access rates are higher. There are no costs for an unlimited number of papers if the submitting author's Institution is a member of BioMed Central http://www.biomedcen- tral.com/inst/. Next, a number of funding agencies explic- itly allow direct use of their grants to covering the article processing charges: • Canadian Institutes of Health Research http://www.cihr- irsc.gc.ca/ • Deutsche Forschungsgemeinschaft http://www.dfg.de/ Published: 31 January 2003 Molecular Cancer 2003, 2:16 Received: 9 January 2003 Accepted: 31 January 2003 This article is available from: http://www.molecular-cancer.com/content/2/1/16 © 2003 Lüttich et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
  • 2. Publish with BioMed Central and every scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical research in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community peer reviewed and publishedimmediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright Submit your manuscript here: http://www.biomedcentral.com/info/publishing_adv.asp BioMedcentral Molecular Cancer 2003, 2 http://www.molecular-cancer.com/content/2/1/16 Page 2 of 2 (page number not for citation purposes) • Fonds zur Förderung der wissenschaftlichen Forschung http://www.fwf.ac.at/ • Health Research Board http://www.hrb.ie/ • Howard Hughes Medical Institute http://www.hh- mi.org/ • International Human Frontier Science Program Organi- zation http://www.hfsp.org/ • Israel Science Foundation http://www.isf.org.il/ • National Health Service http://www.doh.gov.uk/ • National Institutes of Health http://www.nih.gov/ • National Science Foundation http://www.nsf.gov/ • Rockefeller Foundation http://www.rockfound.org/ • Swiss National Science Foundation http://www.snf.ch/ There is further assistance in publication costs. The Soros Foundation http://www.soros.org/ allows authors from certain countries to apply for help in getting manuscripts published. Conclusion Molecular Cancer is an open-access and on-line journal; its publisher fulfills the Freedom of Information Act and guarantees access to papers without barriers and fees. Mo- lecular Cancer does not charge for colored pictures, amount of data presented in the paper and/or supplemen- tal data, page charges etc. BioMed Central charges a flat fee of $500 after a paper is being accepted for publication; in return, the authors retain their copyright. A number of funding agencies explicitly allow direct use of their grants to cover article processing charges; there are no costs for an unlimited number of accepted papers if the submit- ting author's Institution is a member of BioMed Central. Authors' contributions CS drafted the paper, and KL and GS provided suggestions and comments to the paper. All authors read and ap- proved the final manuscript. References 1. Hebert RS, Wright SM, Dittus RS and Elasy TA Prominent medical journals often provide insufficient information to assess the validity of studies with negative results. J Negat Results Biomed 2002, 1:1 2. Pfeffer C and Olsen BR Editorial: Journal of Negative Results in Biomedicine. J Negat Results Biomed 2002, 1:2 3. Verma IM Censorship of scientific publications: a bad idea. Mol Ther 2002, 5:337 4. Trayhurn P The public library of science and "open access" to the scientific literature. Br J Nutr 2002, 87:1-2 5. Suber P Open access to the scientific journal literature. J Biol 2002, 1:3 6. Delamothe T "Author pays" may be the new science publish- ing model BMJ 2003, 326:182 7. Smith R The market for medical journals is anticompetitive, says expert BMJ 2003, 326:182 8. Eaton L "Free" medical publishing venture gets under way. BMJ 2003, 326:11 9. Nenadic G, Mima H, Spasic II, Ananiadou S and Tsujii J Terminology- driven literature mining and knowledge acquisition in bio- medicine. Int J Med Inf 2002, 67:33-48 10. Grivell L Mining the bibliome: searching for a needle in a hay- stack? New computing tools are needed to effectively scan the growing amount of scientific literature for useful infor- mation. EMBO Rep 2002, 3:200-203 11. Schmidt C Bench and Bedside. Mol Cancer 2002, 1:1 12. Lynch C, Tycko B, Bestor T and Walsh C Reactivation of a si- lenced H19 gene in human rhabdomyosarcoma by demeth- ylation of DNA but not by histone hyperacetylation. Mol Cancer 2002, 1:2 13. Arias-Pulido H, Narayan G, Vargas H, Mansukhani M and Murty VV Mapping common deleted regions on 5p15 in cervical carci- noma and their occurrence in precancerous lesions. Mol Can- cer 2002, 1:3 14. Ohnishi K, Ota I, Yane K, Takahashi A, Yuki K, Emoto M, Hosoi H and Ohnishi T Glycerol as a chemical chaperone enhances radia- tion-induced apoptosis in anaplastic thyroid carcinoma cells. Mol Cancer 2002, 1:4 15. Gao X, Loggie B and Nawaz Z The roles of sex steroid receptor coregulators in cancer. Mol Cancer 2002, 1:7 16. Zhang P, Gao W, Turner S and Ducatman BS Gleevec (STI-571) in- hibits lung cancer cell growth (A549) and potentiates the cis- platin effect in vitro. Mol Cancer 2003, 2:1 17. Moore PS, Beghelli S, Zamboni G and Scarpa A Genetic abnormal- ities in pancreatic cancer. Mol Cancer 2003, 2:7 18. Juhasz M, Nitsche B, Malfertheiner P and Ebert MP Implications of growth factor alterations in the treatment of pancreatic can- cer. Mol Cancer 2003, 2:5 19. Carew JS and Huang P Mitochondrial defects in cancer. Mol Can- cer 2002, 1:9 20. Wheatley D and Grynszpan D Can we speed up the online pub- lishing process? And who will pay for it, anyway? Cancer Cell Int 2002, 2:5 21. Velterop J Author charges are the future. BMC News and Views 2001, 2:2