The Transdermal drug delivery and monitoring system (BI-1) allows medication to be administered through the skin via patch or micro device and senses changes in a patient's bloodstream to instantly administer medication when needed to stabilize health issues like low glucose levels. It provides analytics reporting to patients and doctors through a portal to track biological trends over time for improved care. The system aims to increase convenience by delivering smart medication without pills and providing free analytics data to help determine a patient's most vulnerable periods.