CASE PRESENTATION ON GASTROENTRITIS. GE is the inflammation of stomach and small intestine.

1. CASE PRESENTATION ON
GASTROENTERITIS
PRESENTED BY:
CH.BINDU MADHAVI
III/VI PHARMD
Y17PHD0805
DEPARTMENT OF PHARMACY PRACTICE

2. Brief summary about the case:
• A female patient of age 47 years was admitted in the hospital with
C/O loose stools and vomitings since 2 days associated with
abdominal discomfort and generalized weakness.
• She is diagnosed as having ACUTE GASTROENTRITIS.
• Followed by standard treatment the patient was normalized.
• The above case was presented in the form of SOAP analysis.

3. SUBJECTIVE DATA:
• A female patient of age 47 years was admitted in the hospital with
C/O loose stools and vomitings since 2 days associated with
abdominal discomfort and generalized weakness.
• She is having past history of polyarthralgia.
• Her sleep, appetite, bowel and bladder habits are normal.

4. OBJECTIVE DATA:
• PHYSICAL EXAMINATIONS:
Pt- conscious BP- 110/80mmHg PR- 86 beats/min
RR- 18 cycles/min Sp𝑂2 - 98% 𝑃0 𝐼0 𝐶0 𝐶0 𝐿0 𝐸0
• SYSTEMIC EXAMINATIONS:
CVS- 𝑆1 𝑆2
+
RS - BA𝐸+
P/A- soft
CNS- NFND

5. LABORATORY INVESTIGATIONS:
Hematology Observed value Normal value
Platelet count 50,000/cu.mm 1,50,000 – 4,00,000
LFT Observed value Normal value
Bilirubin test 0.48mg/dl 0.00 – 0.30
SGOT/AST 555 IU/L 0-32
SGPT/ALT 268 IU/L 0-33
Total protein 5.7g/dl 6.4-8.3
Serum albumin 2.6g/dl 3.2-5.2
ALB/GLOB ratio 0.84 1.10-1.80

6. OTHER INVESTIGATIONS:
• REAL TIME ULTRASONOGRAPHY OF THE ABDOMEN AND
PELVIS:
• IMPRESSION- Grade II fatty liver
Gall bladder wall edema
Minimal ascites
Circumferential wall thickening of caecum and
proximal ascending colon.
Maximum wall thickness 6mm infective/inflammatory

7. ASSESSMENT:
• Based on the subjective and objective data the final diagnosis was
found to be ACUTE GASTROENTRITIS.
• Based on diarrhea and emesis since 2 days..
• DEFINITION: It is the inflammation
of the stomach and intestines typically
resulting from bacterial toxins or viral
infections and causing vomiting and
diarrhea.

8. • ETIOLOGY: The main cause of gastroenteritis in the above case is
IDIOPATHIC.
• Other causes include viruses, bacteria, parasites and fungus.
• RISK FACTORS:
• Medications use like NSAID
• Certain foods such as lactose
and glutein
• Transmission through contaminated
water or sharing personnel objects.

9. PATHOPHYSIOLOGY:

10. CLINICAL PRESENTATIONS:
• Diarrhea
• Vomiting
• Abdominal discomfort
• Fever
• Head ache
• Muscle pain
• Dehydration

11. STANDARD TREATMENT:
• Rehydration
• Probiotics
• Antiemetics like ondansetron, metoclopramide
• Antibiotics
• Antimotility agents like loperamide, bismuth subsalicylate
• GOALS:
• To reduce signs and symptoms using symptomatic therapy
• To reduce disease progression
• To prevent further complications.

12. Drug information:
S.N
O
NAME OF THE
DRUG
DO
SE
R
O
A
FR
EQ
CATEGORY INDICATIO
N
MOA ADR MP
1. TAB.RCIFAX
(RIFAXIMIN)
400
mg
P/
O
BD Miscellaneous
antibiotics.
To treat
bacterial
infections
Blocks growth of
MO by interfering
with bacterial cell.
Black or
tarry stools,
blood in
urine.
Monitor
hematologic
functions.
2. TAB.XBIOTIC 1
tab
P/
O
BD Dietary
supplement
Used to
promote
normal
bacterial flora.
Act as temporary
flora to re-
establish normal
GI flora
Constipation
, thirst,
flactulence
-----
3. TAB.DOLO
(PARACETAMOL)
650
mg
P/
O
SO
S
Non-opioid
analgesic
Used as pain
reliver.
Activation of
descending
serotonergic
pathways in CNS.
Nausea or
vomiting,
ulcers,
bleeding
Monitor
liver
functions.
4. TAB.PAN 40
(PANTOPROZOLE)
40
mg
P/
O
OD Proton pump
inhibitor
Prophylactic
drug
Supress gastric
acid secretion by
inhibiting parietal
cells.
Headache,
edema,
vertigo,
dizziness
Monitor
bone loss,
serum
gastrin level.

13. S.
N
O
NAME OF THE
DRUG
DO
SE
RO
A
FR
EQ
CATEGO
RY
INDICATION MOA ADR MP
5. TAB.DPRISE
(CARICA PAPAYA
EXTRACT)
1
tab
P/O BD Platelet
booster
Used to increase
platelets. ------ ------ ------
6. TAB.ZERODOL CR
(ACECLOFENAC)
200
mg
P/O OD NSAID of
acetic acid
derivative
Used to reduce
inflammation
and pain.
Inhibit COX-I and
COX-II leading to
decrease PG
production.
Edema,
HTN, MI,
headache,
rashes.
Monitor
CBC, wt
gain,
LFT,BP.
7. INJ.MAGNEX
FORTE
(CEFOPERAZONE
+ SULBACTAM)
100
+
500
mg
IV BD Cephalospo
-rins 3rd
generation
Used to treat
bacterial
infections.
Inhibit cell wall
synthesis in bacteria
Headache,
rash, nausea,
vomiting
Monitor
serum
antibiotic
levels.
8. TAB.URCOSOL
(URSODEOXYCH
OLIC ACID)
300
mg
P/O BD Gall stone
dissolving
agent
Used to
decrease SGOT
and SGPT
levels.
Decrease cholesterol
content of bile stones
by decreasing
cholesterol
production from
liver.
Bladder pain,
dizziness,
fast heart
beat,
indigestion
Monitor
AST, ALT ,
LFT.
• NO DRUG DRUG INTERACTIONS WERE OBSERVED.

14. PATIENT COUNSELLING:
ABOUT DISEASE:
• Gastroenteritis also known as infectious diarrhea, is inflammation of the
gastrointestinal tract.
• It is usually caused by virus, bacteria, parasites and fungus.
ABOUT DRUGS:
TAB.RIFAMIXIN- administer with or without regard to food
TAB.DOLO- administer without regard to food
TAB.PAN 40- administer early morning on empty stomach
TAB.URCOSOL- should be taken with food

15. LIFESTYLE MODIFICATIONS:
• Get plenty of rest.
• Drink clear liquids like apple, grape or cranberry juice.
• Quiet smoking
• Limit alcohol consumption
• Control stress
• Eat healthy foods
• Wash your hands thoroughly before eating food.