It is based on fungicides used to kill pathogens. It elaborates on the properties and function of Orysastrobin and Famoxadone.

1. A PRESENTATION
ON
ORYSASTROBIN &
FAMOXADONE

2. Name of fungicide- ORYSASTROBIN (ISOPA)
Formula: C18H25N5O5.
Class: Strobilurin
Trade Name: ARASHI
Basic Producers: BASF
Corporation (Arashi*)
Fig: chemical structure of orysastrobin

3. Mode of Action / Resistance Management
Chemical Group: oximino acetamide
Taget Site: C3: complex III cytochrome bc1 (ubiquinol
oxidase) at Qo site
Mode of Action: Systemic, broad spectrum with
protective and curative properties. Interferes with
the respiration process.
Action Group: FRAC Code 11
Comments / Risk Notes: HIGH RISK
*Orysastrobin is basically used against Rice blast.

4. Some points about ORYSASTROBIN
Orysastrobin is a rice fungicide without EU regulatory
approval for use.
It has a moderate aqueous solubility, is non-volatile and,
based on its chemical properties, is mobile and can be
expected to leach to groundwater.
It is generally moderately persistent in soil systems but will
not usually persist in aquatic systems under certain
conditions.
It is not generally susceptible to hydrolysis.
It has a moderate mammalian toxicity and has a high
potential to bioaccumulate.
It is moderately toxic to most aquatic species, birds and
earthworms but relatively non-toxic to honey bees.

5. Name of fungicide- FAMOXADONE (ISOPA ANSI,
BSI, )
Formula: C22H18N2O4
Class: Strobilurin
Trade Name: TANOS* Equation*
Contact, Equation* Pro
Basic Producers: DuPont Crop
Protection (Famoxate*)
Shanghai MingDou Chemical
Co., Ltd.
Fig: chemical structure of Famoxadone

6. Mode of Action / Resistance Management
Chemical Group: oxazolidinedione
Taget Site: C3: complex III cytochrome bc1 (ubiquinol
oxidase) at Qo site
Mode of Action: Systemic, broad spectrum & act on
respiration process.
Action Group: FRAC Code 11
Comments / Risk Notes: HIGH RISK
Toxicity: (Rat): Oral LD50 >5000 mg/kg; Dermal LD50
>2000 mg/kg
*Famoxadone is used on cucurbits, head lettuce, peppers, potatoes,
tomatoes. Under development for cereals and grapes.

7. Some points about FAMOXADONE
 Famoxadone (DPX-JE874, Famoxate®) inhibited sporangial
differentiation and zoospore release and caused lysis of zoospores within
minutes.
 Doses in the order of 0.01 mg l−1 were sufficient to lyse zoospores of both
Plasmopara viticola and Phytophthora infestans.
 In the case of P.infestans, mycelial growth and direct germination of
sporangia were also inhibited but higher doses were needed.
 In whole plant tests, famoxadone exhibited strong preventative control of
both grape downy mildew and potato late blight with good residual
activity of at least 7–10 days.
 No significant effect on disease control was observed when famoxadone
was applied after inoculation.
 Both the in vitro and in vivo activities of famoxadone appeared
complementary to that of cymoxanil which exhibited shorter residual
activity but strong curative properties.

8. Doses of famoxadone in different crop
• Grape Vines @3 times at 0.3 kg ai/ha
• Tomato @0.63 kg ai/ha
• Potato @ 3 times at 0.3 kg ai/ha(in
greenhouse)
• Mature Wheat Plants @ 3 applications at
0.2 kg ai/ha