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Liver Function Test
Happy is Healthy
Liver Function Test
• Liverfunctiontesthelpstodeterminethehealthofyourliverby
measuringthelevelofproteins,liverenzymes,orbilirubinin
yourblood.
When do you need a Liver Function
Test???
• Ifyouhavesymptoms,toscreenforanypotentialliverproblemsor
infectionsaffectingtheliversuchashepatitisA,hepatitisBandhepatitisC.
• Toaidinthediagnosisofotherconditionssuchasgallstones.
• Whenyouhaveliverdisease,tomonitortheprogressionandseverityofthe
disease,andtodeterminehowwellatreatmentisworking
• Tomonitorsideeffects,ifyouaretakingprescription,ornon-prescription
medicinesthatcanaffectyourliverfunction.
Why do you need a Liver Function Test:
• Removingcontaminantsfromyourblood
• Convertingnutrientsfromthefoodsyoueat
• Storingmineralsandvitamins
• Regulatingbloodclotting
• Producingproteins,enzymes,andbile
• Makingfactorsthatfightinfection
• Removingbacteriafromyourblood
• Processingsubstancesthatcouldharmyourbody
• Maintaininghormonebalances
Common Tests for Liver Function Test
• AlanineTransaminase(SGPT)
• AlkalinePhosphatase
• Bilirubin–(Direct,Indirect,Total)
• GammaGlutamy|Transferase(GGT)
• Protein-Total
• SerumAlbumin
• SerumGlobulin
• AspartateAminotransferase(SGOT)
• SerumAlbumin/GlobulinRatio
Alanine Transaminase (SGPT)
• Alanine Transaminase isusedbyyourbodytometabolizeprotein
• Iftheliverisdamagedornotfunctioningproperly,AlanineTransaminase
isreleasedintotheblood.
• ThiscausesAlanine Transaminase levelstoincrease.
• AhighresultonthistestcanbesignofLiverdamage.
• Doctorwillprescribeyouthistestifyouhavesymptomslike:Vomiting,
Weakness,Extremetiredness,Dark-coloredUrine,Itchyskin,orJaundice
Alkaline Phosphate :
• AlkalinePhosphate(ALP)isanenzyme foundinBones,bileductsandLiver.
• AnAlkalinePhosphateistypicallyorderedincombinationwithseveralother
tests.
• HighlevelofAlkalinePhosphatemayindicateliverdamage,blockageofthebile
ducts,orabonedisease.
• Childrenandadolescents mayhaveelevated levelsofALPbecausetheirbonesare
growing.Pregnancy canalsoraiseALPlevels.
• NormalrangeforALPIs(45–115)U/L.
• LowlevelsofALPcanoccurfollowingabloodtransfusionorheartbypass surgery.
• LowlevelofALPcanresultfromazincdeficiency ormalnutrition.
Aspartate aminotransferase (SGOT) :
• Aspartateaminotransferaseisanenzymefoundinseveralpartsofyourbody
including,theheart,liverandmuscles.
• SinceAspartateaminotransferaselevelsaren’tspecificforliverdamage,it’s
usuallymeasured togetherwithAlanineTransferase tocheckliverproblems.
• Whenliverisdamaged,Aspartatetransferaseisreleasedintothebloodstream.
• AhighlevelofAspartateaminotransferasetestmightindicateaproblemwith
liverormuscle.
• Thenormalrangeforthistestis8-48U/L.
Bilirubin test :
• Bilirubinisawasteproductfrombreakdownofredbloodcells.It’sordinarilyprocessed
byliver.
• Itpassesthroughtheliverbeforebeingexcretedthroughyourstool.
• Adamagedlivercan’tproperlyprocessBilirubin,sothisleadstoanabnormallyhigh
levelofBilirubinintheblood.
• Ahighresultonthebilirubintestindicatesthattheliverisn’tfunctioning properly
• Henormalrangeforbilirubinis0.1–1.2mg/dL
a) IndirectBilirubin:Bilirubinnotattachedtoglucuronic.
b) TotalBilirubin:Allthebilirubininyourbloodtogether.(0.3-1.9mg/dL)
Serum Albumin test :
• Albuministhemainproteinmadebyyourliver.Itperformsmanyimportantbodily
functions,Suchas:
 Stopfluidfromleakingoutofyourbloodvessels.
 Nourishesyourtissues.
 Transportshormones,vitaminsandothersubstancesthroughout yourbody.
• Analbumintestmeasureshowwellyourliverismakingthisparticularprotein.Alow
resultonthistestindicatesthatyourliverisn’tfunctioningproperly.
• Thenormalrangeforalbuminis(3.5–5.0)gramsperdeciliter(g/dL).
Gamma-Glutamyl Transferase(GGT):
• TheGamma-glutamyltranferasetestmeasurestheamountofenzymeinyour
blood.
• Sinceenzymesaremoleculesthatarenecessaryforchemicalreactioninyour
body,SoGamma-glutamyltransferasefunctionsinthebodyasatransport
moleculehelpingtomoveothersmoleculesaroundthebody.
• Itplaysasignificantroleinhelpingthelivermetabolizedrugs&othertoxins.
• Thistestbeingprescribedbydoctorifhesuspectsyourliverdamagedueto
heavyalcoholuseoranytoxicsubstanceslikedrugs/poison.
Serum Globulin test :
• Globulinsareagroupofproteinsinyourblood.Theyaremadeinyourliverbyyour
immunesystem.Globulinsplayanimportantroleinliverfunction,bloodclotting,and
fightinginfection.
• Atotalproteintestmaybeincludedinaseriesofteststocheckhowwellyourliveris
working.
• Globulintestsarebloodtests.Duringabloodtest,ahealthcareprofessionalwilltakea
bloodsamplefromaveininyourarm,usingasmallneedle.
• Lowglobulinlevelscanbeasignofliverorkidneydisease.
• Highglobulinlevelsmayalsoindicatecertaintypesofcancer,suchasmultiple
myeloma,Hodgkin'sdisease.
COST@
LIVER FUNCTION TEST
Market Price (in Gen.)
• Price for Multiple cities in India
@Rs.1000/-INR only
@BookMyScans
• Price in Multiple cities in India @Rs.400/-
• Package includes (11 tests) :
 Serum Albumin / Globulin Ratio
 Alkaline Phosphatase
 Bilirubin - Direct
 Bilirubin - Indirect
 Bilirubin - Total
 Gamma Glutamy|Transferase (GGT)
 Protein - Total
 Serum Albumin
 Serum Globulin
 Aspartate Aminotransferase (SGOT)
 Alanine Transaminase (SGPT)
Liver Function Test | A must needed precautionary act

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Liver Function Test | A must needed precautionary act

  • 2. Liver Function Test • Liverfunctiontesthelpstodeterminethehealthofyourliverby measuringthelevelofproteins,liverenzymes,orbilirubinin yourblood.
  • 3. When do you need a Liver Function Test??? • Ifyouhavesymptoms,toscreenforanypotentialliverproblemsor infectionsaffectingtheliversuchashepatitisA,hepatitisBandhepatitisC. • Toaidinthediagnosisofotherconditionssuchasgallstones. • Whenyouhaveliverdisease,tomonitortheprogressionandseverityofthe disease,andtodeterminehowwellatreatmentisworking • Tomonitorsideeffects,ifyouaretakingprescription,ornon-prescription medicinesthatcanaffectyourliverfunction.
  • 4. Why do you need a Liver Function Test: • Removingcontaminantsfromyourblood • Convertingnutrientsfromthefoodsyoueat • Storingmineralsandvitamins • Regulatingbloodclotting • Producingproteins,enzymes,andbile • Makingfactorsthatfightinfection • Removingbacteriafromyourblood • Processingsubstancesthatcouldharmyourbody • Maintaininghormonebalances
  • 5. Common Tests for Liver Function Test • AlanineTransaminase(SGPT) • AlkalinePhosphatase • Bilirubin–(Direct,Indirect,Total) • GammaGlutamy|Transferase(GGT) • Protein-Total • SerumAlbumin • SerumGlobulin • AspartateAminotransferase(SGOT) • SerumAlbumin/GlobulinRatio
  • 6. Alanine Transaminase (SGPT) • Alanine Transaminase isusedbyyourbodytometabolizeprotein • Iftheliverisdamagedornotfunctioningproperly,AlanineTransaminase isreleasedintotheblood. • ThiscausesAlanine Transaminase levelstoincrease. • AhighresultonthistestcanbesignofLiverdamage. • Doctorwillprescribeyouthistestifyouhavesymptomslike:Vomiting, Weakness,Extremetiredness,Dark-coloredUrine,Itchyskin,orJaundice
  • 7. Alkaline Phosphate : • AlkalinePhosphate(ALP)isanenzyme foundinBones,bileductsandLiver. • AnAlkalinePhosphateistypicallyorderedincombinationwithseveralother tests. • HighlevelofAlkalinePhosphatemayindicateliverdamage,blockageofthebile ducts,orabonedisease. • Childrenandadolescents mayhaveelevated levelsofALPbecausetheirbonesare growing.Pregnancy canalsoraiseALPlevels. • NormalrangeforALPIs(45–115)U/L. • LowlevelsofALPcanoccurfollowingabloodtransfusionorheartbypass surgery. • LowlevelofALPcanresultfromazincdeficiency ormalnutrition.
  • 8. Aspartate aminotransferase (SGOT) : • Aspartateaminotransferaseisanenzymefoundinseveralpartsofyourbody including,theheart,liverandmuscles. • SinceAspartateaminotransferaselevelsaren’tspecificforliverdamage,it’s usuallymeasured togetherwithAlanineTransferase tocheckliverproblems. • Whenliverisdamaged,Aspartatetransferaseisreleasedintothebloodstream. • AhighlevelofAspartateaminotransferasetestmightindicateaproblemwith liverormuscle. • Thenormalrangeforthistestis8-48U/L.
  • 9. Bilirubin test : • Bilirubinisawasteproductfrombreakdownofredbloodcells.It’sordinarilyprocessed byliver. • Itpassesthroughtheliverbeforebeingexcretedthroughyourstool. • Adamagedlivercan’tproperlyprocessBilirubin,sothisleadstoanabnormallyhigh levelofBilirubinintheblood. • Ahighresultonthebilirubintestindicatesthattheliverisn’tfunctioning properly • Henormalrangeforbilirubinis0.1–1.2mg/dL a) IndirectBilirubin:Bilirubinnotattachedtoglucuronic. b) TotalBilirubin:Allthebilirubininyourbloodtogether.(0.3-1.9mg/dL)
  • 10. Serum Albumin test : • Albuministhemainproteinmadebyyourliver.Itperformsmanyimportantbodily functions,Suchas:  Stopfluidfromleakingoutofyourbloodvessels.  Nourishesyourtissues.  Transportshormones,vitaminsandothersubstancesthroughout yourbody. • Analbumintestmeasureshowwellyourliverismakingthisparticularprotein.Alow resultonthistestindicatesthatyourliverisn’tfunctioningproperly. • Thenormalrangeforalbuminis(3.5–5.0)gramsperdeciliter(g/dL).
  • 11. Gamma-Glutamyl Transferase(GGT): • TheGamma-glutamyltranferasetestmeasurestheamountofenzymeinyour blood. • Sinceenzymesaremoleculesthatarenecessaryforchemicalreactioninyour body,SoGamma-glutamyltransferasefunctionsinthebodyasatransport moleculehelpingtomoveothersmoleculesaroundthebody. • Itplaysasignificantroleinhelpingthelivermetabolizedrugs&othertoxins. • Thistestbeingprescribedbydoctorifhesuspectsyourliverdamagedueto heavyalcoholuseoranytoxicsubstanceslikedrugs/poison.
  • 12. Serum Globulin test : • Globulinsareagroupofproteinsinyourblood.Theyaremadeinyourliverbyyour immunesystem.Globulinsplayanimportantroleinliverfunction,bloodclotting,and fightinginfection. • Atotalproteintestmaybeincludedinaseriesofteststocheckhowwellyourliveris working. • Globulintestsarebloodtests.Duringabloodtest,ahealthcareprofessionalwilltakea bloodsamplefromaveininyourarm,usingasmallneedle. • Lowglobulinlevelscanbeasignofliverorkidneydisease. • Highglobulinlevelsmayalsoindicatecertaintypesofcancer,suchasmultiple myeloma,Hodgkin'sdisease.
  • 13. COST@ LIVER FUNCTION TEST Market Price (in Gen.) • Price for Multiple cities in India @Rs.1000/-INR only @BookMyScans • Price in Multiple cities in India @Rs.400/- • Package includes (11 tests) :  Serum Albumin / Globulin Ratio  Alkaline Phosphatase  Bilirubin - Direct  Bilirubin - Indirect  Bilirubin - Total  Gamma Glutamy|Transferase (GGT)  Protein - Total  Serum Albumin  Serum Globulin  Aspartate Aminotransferase (SGOT)  Alanine Transaminase (SGPT)