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•Irsa Ali
•Nimra Maheen
•Liver Diseases and
Their Medical Nutrition
Therapy
Liver:-
THE LIVER IS A VITAL ORGAN
THAT PERFORMS MANY
IMPORTANT FUNCTIONS IN
THE BODY.
FUNCTIONS OF THE LIVER: •METABOLISM OF NUTRIENTS •DETOXIFICATION OF
HARMFUL SUBSTANCES
•PRODUCTION OF BILE
•STORAGE OF VITAMINS AND
MINERALS
•PRODUCTION OF BLOOD
CLOTTING FACTORS
Liver function tests (LFTs)
LFTs are a group of blood
tests that can provide
information about the health
of the liver and help
diagnose liver disorders.
Some common LFTs include:
•Alanine aminotransferase
(ALT)
•Aspartate aminotransferase
(AST)
•Alkaline phosphatase(ALP)
•Total bilirubin •Albumin •Prothrombin time (PT)
Viral hepatitis:-
•Viral hepatitis is a type of
liver disorder caused by a viral
infection.
•There are several types of
viral hepatitis, including
hepatitis A, B, C, D, and E. Each
type of viral hepatitis is caused
by a different virus and has its
own unique characteristics
Viral hepatitis:-
•Hepatitis A:
It is usually transmitted through contaminated food or water and causes an acute infection.
•Hepatitis B:
It is transmitted through blood, semen, or other body fluids and can cause both acute and chronic
liver infection.
•Hepatitis C:
It is also transmitted through blood and can cause both acute and chronic liver infections.
•Hepatitis D:
It is a rare form of viral hepatitis that only occurs in people who are already
infected with hepatitis B. Hepatitis D can cause acute and chronic liver infections
and can lead to serious complications.
•Hepatitis E:
It is transmitted through contaminated food or water and is most common in
developing countries. It usually causes an acute infection and does not usually
cause chronic liver disease.
MNT for viral hepatitis
Here are some general guidelines for MNT for viral hepatitis:
•Adequate protein intake
•Avoidance of alcohol
•Moderate fat intake
•Avoidance of hepatotoxic drugs and supplements
•Adequate calorie intake
•Hydration
•Individualized recommendations
Diet planing:-
It is important for people with viral hepatitis to follow a balanced and healthy diet to support liver function and overall health. Here are some
drink and food recipe ideas for viral hepatitis patient
•Breakfast:
Oatmeal/ Scrambled eggs/ Fruit salad
•Lunch:
Grilled chicken salad/ Lentil and vegetable soup
•Dinner:
Baked salmon/ Grilled chicken with sautéed veggies
•Snack:-
Apple slices with almond butter/ Greek yogurt with friuts / Fruit smoothie/fruit salad
Liver Cirrhosis
•Cirrhosis occurs as a s result of excessive alcohol intake,
most common viral hepatitis, obstruction of the bile ducts,
and exposure to certain drugs or toxic substances. It is also
found in highly malnourished children.
• Liver cirrhosis is a chronic disease in which there is
considerable damage to its cells with infiltration by fats and
fibrosis.
• Symptoms include loss of appetite nausea, vomiting and
weight loss, giving an emaciated appearance.
Diet:
•Patients with cirrhosis
require a balanced diet
providing 2000-3,000
calories a day to allow the
liver cells to regenerate.
Thus the diet recommended
is a high-calorie, adequate
protein diet with vitamin
and mineral supplements.
Too much protein will result
in an increased amount of
ammonia in the blood, and
too little protein can reduce
healing of the liver.
Portal Hypertension
• Portal hypertension is one of the most serious complications
of advanced liver disease. Scar tissue in your liver (cirrhosis)
compresses the blood vessels running through it and reduces
their blood flow
Symptoms of portal hypertension
•Blood in vomit.
•Blood in poop.
•Bloated stomach with rapid weight gain (from fluid).
•Swelling in your legs and feet (edema).
•Mental confusion or disorientation.
MNT for portal HTN
•Sodium restriction •Protein intake •Fluid restriction
•Adequate calorie
intake
•Avoid alcohol
•Vitamin and mineral
supplements
•Fiber intake
Hepatic Encephalopathy
•Hepatic encephalopathy is a nervous system disorder brought
on by severe liver disease. When the liver doesn’t work
properly, toxins build up in the blood. These toxins can travel to
the brain and affect brain function
Types of hepatic
encephalopathy
•There are three types of hepatic
encephalopathy:
•Type A is brought on by acute liver
failure (without underlying chronic liver
disease).
•Type B occurs in some people who have a
shunt that connects two veins inside the liver
without underlying liver disease.
•Type C results from chronic liver disease and
scarring (cirrhosis)
SYMPTOMS
•Anxiety or irritability. •Cognitive impairment
(confused thinking or
judgment).
•Coordination
or balance problems.
•Difficulty concentrating
or short attention span.
MNT for encephalopathy
•Protein should be severely
restricted (18–20g/day)
sometimes even 0 per day.
Maintenance of nitrogen
balance is difficult.
• Intravenous feeding may be
used in some cases.
Hypertonic dextrose solution
with 37–50% BCAA and low in
AAA should be administered.
•Alfa Keto analogs of BCAA
can also be given. All measures
to reduce ammonia
(previously mentioned) should
be taken.
• Fat solution containing 75%
medium-chain triglycerides
and 25% long chain
triglycerides may be better
utilized.
• Attention to electrolyte
balance as well as acid-base
status is equally important.
• Supplements of water and
fat-soluble vitamins should be
given. The patient should be
shifted to enteral feeding as
soon as possible.
•Enteral nutrition maintains
intestinal membrane integrity
thus preventing bacterial
translocation and subsequent
multiple organ failure in
critically ill patients.

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LIVER DIS AND MNT

  • 1. •Irsa Ali •Nimra Maheen •Liver Diseases and Their Medical Nutrition Therapy
  • 2. Liver:- THE LIVER IS A VITAL ORGAN THAT PERFORMS MANY IMPORTANT FUNCTIONS IN THE BODY. FUNCTIONS OF THE LIVER: •METABOLISM OF NUTRIENTS •DETOXIFICATION OF HARMFUL SUBSTANCES •PRODUCTION OF BILE •STORAGE OF VITAMINS AND MINERALS •PRODUCTION OF BLOOD CLOTTING FACTORS
  • 3. Liver function tests (LFTs) LFTs are a group of blood tests that can provide information about the health of the liver and help diagnose liver disorders. Some common LFTs include: •Alanine aminotransferase (ALT) •Aspartate aminotransferase (AST) •Alkaline phosphatase(ALP) •Total bilirubin •Albumin •Prothrombin time (PT)
  • 4. Viral hepatitis:- •Viral hepatitis is a type of liver disorder caused by a viral infection. •There are several types of viral hepatitis, including hepatitis A, B, C, D, and E. Each type of viral hepatitis is caused by a different virus and has its own unique characteristics
  • 5. Viral hepatitis:- •Hepatitis A: It is usually transmitted through contaminated food or water and causes an acute infection. •Hepatitis B: It is transmitted through blood, semen, or other body fluids and can cause both acute and chronic liver infection. •Hepatitis C: It is also transmitted through blood and can cause both acute and chronic liver infections.
  • 6. •Hepatitis D: It is a rare form of viral hepatitis that only occurs in people who are already infected with hepatitis B. Hepatitis D can cause acute and chronic liver infections and can lead to serious complications. •Hepatitis E: It is transmitted through contaminated food or water and is most common in developing countries. It usually causes an acute infection and does not usually cause chronic liver disease.
  • 7. MNT for viral hepatitis Here are some general guidelines for MNT for viral hepatitis: •Adequate protein intake •Avoidance of alcohol •Moderate fat intake •Avoidance of hepatotoxic drugs and supplements •Adequate calorie intake •Hydration •Individualized recommendations
  • 8. Diet planing:- It is important for people with viral hepatitis to follow a balanced and healthy diet to support liver function and overall health. Here are some drink and food recipe ideas for viral hepatitis patient •Breakfast: Oatmeal/ Scrambled eggs/ Fruit salad •Lunch: Grilled chicken salad/ Lentil and vegetable soup •Dinner: Baked salmon/ Grilled chicken with sautéed veggies •Snack:- Apple slices with almond butter/ Greek yogurt with friuts / Fruit smoothie/fruit salad
  • 9. Liver Cirrhosis •Cirrhosis occurs as a s result of excessive alcohol intake, most common viral hepatitis, obstruction of the bile ducts, and exposure to certain drugs or toxic substances. It is also found in highly malnourished children. • Liver cirrhosis is a chronic disease in which there is considerable damage to its cells with infiltration by fats and fibrosis. • Symptoms include loss of appetite nausea, vomiting and weight loss, giving an emaciated appearance.
  • 10. Diet: •Patients with cirrhosis require a balanced diet providing 2000-3,000 calories a day to allow the liver cells to regenerate. Thus the diet recommended is a high-calorie, adequate protein diet with vitamin and mineral supplements. Too much protein will result in an increased amount of ammonia in the blood, and too little protein can reduce healing of the liver.
  • 11. Portal Hypertension • Portal hypertension is one of the most serious complications of advanced liver disease. Scar tissue in your liver (cirrhosis) compresses the blood vessels running through it and reduces their blood flow
  • 12. Symptoms of portal hypertension •Blood in vomit. •Blood in poop. •Bloated stomach with rapid weight gain (from fluid). •Swelling in your legs and feet (edema). •Mental confusion or disorientation.
  • 13. MNT for portal HTN •Sodium restriction •Protein intake •Fluid restriction •Adequate calorie intake •Avoid alcohol •Vitamin and mineral supplements •Fiber intake
  • 14. Hepatic Encephalopathy •Hepatic encephalopathy is a nervous system disorder brought on by severe liver disease. When the liver doesn’t work properly, toxins build up in the blood. These toxins can travel to the brain and affect brain function
  • 15. Types of hepatic encephalopathy •There are three types of hepatic encephalopathy: •Type A is brought on by acute liver failure (without underlying chronic liver disease). •Type B occurs in some people who have a shunt that connects two veins inside the liver without underlying liver disease. •Type C results from chronic liver disease and scarring (cirrhosis)
  • 16. SYMPTOMS •Anxiety or irritability. •Cognitive impairment (confused thinking or judgment). •Coordination or balance problems. •Difficulty concentrating or short attention span.
  • 17. MNT for encephalopathy •Protein should be severely restricted (18–20g/day) sometimes even 0 per day. Maintenance of nitrogen balance is difficult. • Intravenous feeding may be used in some cases. Hypertonic dextrose solution with 37–50% BCAA and low in AAA should be administered. •Alfa Keto analogs of BCAA can also be given. All measures to reduce ammonia (previously mentioned) should be taken. • Fat solution containing 75% medium-chain triglycerides and 25% long chain triglycerides may be better utilized. • Attention to electrolyte balance as well as acid-base status is equally important. • Supplements of water and fat-soluble vitamins should be given. The patient should be shifted to enteral feeding as soon as possible. •Enteral nutrition maintains intestinal membrane integrity thus preventing bacterial translocation and subsequent multiple organ failure in critically ill patients.