Module 3 kidney and liver function


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Module 3 kidney and liver function

  1. 1. Kidney and Liver Function
  2. 2. BUN: Blood Urea Nitrogen See if your kidneys are working normally. See if your kidney disease is getting worse. • See if treatment of your kidney disease treatment is working. • Check for severe dehydration. Dehydration generally causes BUN levels to rise more than creatinine levels. This causes a high BUN-to-creatinine ratio. Kidney disease or blockage of the flow of urine from your kidney causes both BUN and creatinine levels to go up. • •
  3. 3. Creatinine • Creatinine is a chemical waste product that's produced by your muscle metabolism and to a smaller extent by eating meat. Healthy kidneys filter creatinine and other waste products from your blood. The filtered waste products leave your body in your urine. • If your kidneys aren't functioning properly, an increased level of creatinine may accumulate in your blood. A serum creatinine test measures the level of creatinine in your blood and gives you an estimate of how well your kidneys filter (glomerular filtration rate).
  4. 4. Total Bilirubin • Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. • A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool. • Large amounts of bilirubin in the blood can lead to jaundice. Jaundice is a yellow color in the skin, mucus membranes, or eyes.
  5. 5. Jaundice • Jaundice is the most common reason to check bilirubin levels. • Most newborns have some jaundice. The doctor or nurse will often check the newborn's bilirubin level. • Jaundice can occur if: • Too many red blood cells are dying or breaking down and going to the liver • The liver is overloaded or damaged • The bilirubin from the liver is unable to move into the digestive tract properly • Jaundice is often a sign of a problem with the liver, gallbladder, or pancreas.
  6. 6. Total Protein • The total protein test measures the total amount of two classes of proteins found in the fluid portion of your blood: albumin and globulin. • Proteins are important parts of all cells and tissues. For example, albumin helps prevent fluid from leaking out of blood vessels. Globulins are an important part of your immune system. • This test is often done to diagnose nutritional problems, kidney disease or liver disease. If total protein is abnormal, further tests must be done to identify the specific problem.