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PRESENTEDBY: DR ZAINAB IQBAL
UNITEDCOLLEGE OF PHYSICAL THERAPY
KARACHI
3
 CEREBRAL CIRCULATION
BLOOD VESSELS OF CEREBRAL
CIRCULATION
CEREBRAL BLOOD FLOW
CHARACTERISTICS OF CEREBRAL
CIRCULATION
BLOOD BRAIN BARRIER
4
4
 The movement of blood through the network
of blood vessels to supply the brain.
 The arteries carries oxygenated blood and
other nutrients to the brain
 The veins carry deoxygenated blood back to
the heart removing carbondioxide and
metabolic products.
 .
5
 Two internal carotid arteries
 Two vertebral arteries form
 (basilar artery)
6
 THESE ALL ARTRIES UNITE TOGETHER TO
FORM CIRCLE OF WILLI FROM WHICH SIX
CEREBRAL ARTRIES ARISES TO SUPPLY THE
BRAIN.
 THE CIRCLE OF WILLI IS A CIRCULATORY
ANASTOMOSIS THAT SUPPLIES BLOOD TO THE
BRAIN AND SURROUNDING STRUCTURES.
7
 THESE ALL ARTRIES UNITE TOGETHER
TO FORM CIRCLE OF WILLI FROM
WHICH SIX CEREBRAL ARTRIES ARISES
TO SUPPLY THE BRAIN.
 THE CIRCLE OF WILLI IS A CIRCULATORY
ANASTOMOSIS THAT SUPPLIES BLOOD
TO THE BRAIN AND SURROUNDING
STRUCTURES.
8
 NORMAL VALUE
 IN ADULT CBF IS 750ML/PM
 AND 50% OF THE CRDIAC OUTPUT
9
The movement of blood in cerebral
circulation is called cerebral blood
flow.
1.CEREBRAL CIRCULATION
 enclosed in solid skull
 Brain tissue blood and CSF volumes remain
same at any time
2.GLUCOSE:
 IT IS MAJOR SOURCE IN BRAIN
10
3.BRAIN
 Loss of conciousness if hypoxia is more than
5 sec.
 Tissue damages if hypoxia is more than 3
min.
HYPOGLYCEMIIA: Condition caused by a very
low level of blood sugar.
11
 BLOOD BRAIN BARRIER IS AN IMPORTANT
CONDUCT OF NUTRITIENTS AND CELLS FROM
THE BLOOD TO THE BRAIN
 IT IS A SEMIPERMEABLE MEMBRANE
SEPARATINGTHE BLOOD FROM THE CSF .
 IT IS A BARRIER TO PASSAGE OF CELLS PARTICLES,
AND LARGE MOLECULES.
12
 It protects the brain from endogenous
and exogenous
 It maintains the local environment of the
neuron in CSF constant
 Preventing the escape of local
neurotransmitters into general circulation
13
FUNCTION
14
15

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Cerebral circulation physiology by zainab iqbal

  • 1. 1
  • 2. 2 PRESENTEDBY: DR ZAINAB IQBAL UNITEDCOLLEGE OF PHYSICAL THERAPY KARACHI
  • 3. 3  CEREBRAL CIRCULATION BLOOD VESSELS OF CEREBRAL CIRCULATION CEREBRAL BLOOD FLOW CHARACTERISTICS OF CEREBRAL CIRCULATION BLOOD BRAIN BARRIER
  • 4. 4 4
  • 5.  The movement of blood through the network of blood vessels to supply the brain.  The arteries carries oxygenated blood and other nutrients to the brain  The veins carry deoxygenated blood back to the heart removing carbondioxide and metabolic products.  . 5
  • 6.  Two internal carotid arteries  Two vertebral arteries form  (basilar artery) 6
  • 7.  THESE ALL ARTRIES UNITE TOGETHER TO FORM CIRCLE OF WILLI FROM WHICH SIX CEREBRAL ARTRIES ARISES TO SUPPLY THE BRAIN.  THE CIRCLE OF WILLI IS A CIRCULATORY ANASTOMOSIS THAT SUPPLIES BLOOD TO THE BRAIN AND SURROUNDING STRUCTURES. 7
  • 8.  THESE ALL ARTRIES UNITE TOGETHER TO FORM CIRCLE OF WILLI FROM WHICH SIX CEREBRAL ARTRIES ARISES TO SUPPLY THE BRAIN.  THE CIRCLE OF WILLI IS A CIRCULATORY ANASTOMOSIS THAT SUPPLIES BLOOD TO THE BRAIN AND SURROUNDING STRUCTURES. 8
  • 9.  NORMAL VALUE  IN ADULT CBF IS 750ML/PM  AND 50% OF THE CRDIAC OUTPUT 9 The movement of blood in cerebral circulation is called cerebral blood flow.
  • 10. 1.CEREBRAL CIRCULATION  enclosed in solid skull  Brain tissue blood and CSF volumes remain same at any time 2.GLUCOSE:  IT IS MAJOR SOURCE IN BRAIN 10
  • 11. 3.BRAIN  Loss of conciousness if hypoxia is more than 5 sec.  Tissue damages if hypoxia is more than 3 min. HYPOGLYCEMIIA: Condition caused by a very low level of blood sugar. 11
  • 12.  BLOOD BRAIN BARRIER IS AN IMPORTANT CONDUCT OF NUTRITIENTS AND CELLS FROM THE BLOOD TO THE BRAIN  IT IS A SEMIPERMEABLE MEMBRANE SEPARATINGTHE BLOOD FROM THE CSF .  IT IS A BARRIER TO PASSAGE OF CELLS PARTICLES, AND LARGE MOLECULES. 12
  • 13.  It protects the brain from endogenous and exogenous  It maintains the local environment of the neuron in CSF constant  Preventing the escape of local neurotransmitters into general circulation 13 FUNCTION
  • 14. 14
  • 15. 15