Dent disease is a rare disorder of the kidney in which reabsorption of filtered solutes is impaired and there is progressive renal failure. R. R. Hoopes and colleagues studied mutations associated with Dent disease in the following family (R. R. Hoopes et al. American Journal of Human Genetics 76:260-267, 2005). On the basis of this pedigree, what is the MOST likely mode of inheritance for the disease? Autosomal recessive X-linked recessive Autosomal dominant X- linked dominant Y-linked. Solution On the basis of pattern of inheritance of particuar traint, The answer is Autosomal recesseve..