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Corneal Causes of
Decreased Vision
Subtitle
By
Dr. Amr Mounir, MD, PhD
Assistant Professor of Ophthalmology,
Sohag University
Introduction
It is the transparent front part of the eye that
covers the iris, pupil, and anterior chamber.
Its refractive power of the cornea is approximately
43 diopters.
Five distinct layers make up the cornea, including
the epithelium, Bowman's membrane, the stroma,
Descemet's membrane, and the endothelium
(from the exterior to interior).
The cornea is the clear outer layer at the front of
the eye.
The cornea focus light together with the lens.
There are several common
Conditions that affect the cornea
Injuries Keratitis
There are several common
Conditions that affect the cornea
Dry eye Corneal Dystrophy
Clinical Picture
.
Causes of decreased vision
Infectious
Bacterial keratitis
Fungal keratitis
Viral keratitis
Trachoma
Onchocerciasis
Leprosy
Causes of decreased vision
Nutritional
Vitamin A deficiency (xerophthalmia)
Inflammatory
Peripheral ulcerative keratitis
Inherited
Corneal stromal dystophies
Fuch's endothelial dystrophy
Causes of decreased vision
Degenerative
Keratoconus
Trauma
Penetrating trauma
Chemical injury
Iatrogenic
Pseudophakic bullous keratopathy
Dry Eye
Important Causes
Keratitis
keratitis
Bacteria and
Fungi Viruses Acanthamoeba
Systemic
Autoimmune/
Inflammatory
Local Toxic
Infectious
Non infectious
Etiology
Diagnostic approaches
1. Determination of the ulcer geography.
2. Categories:
A. infectious
B. noninfectious
3. Talk to your patients.
4. Ask about pain type and severity.
Diagnostic approaches
5. Consider the context.
6. environmental and social factors
7. ocular history
8. Examine the eye :Visual acuity , Ulcer itself
9. Culture the site of ulcer
Trachoma
Xerophthalmia
Peripheral ulcerative keratitis
Non INFECTIOUS
INFECTIOUS
No pain
Pain
No discharge
Discharge
AC reaction: absent
AC reaction: present
Peripheral
Central
Trauma: -------
Trauma : ++++
Peripheral ulcerative keratitis
Mooren's ulcer
Terrien's Marginal Degeneration
Corneal dystophies
Fuchs’ corneal endothelial dystrophy
ECTATIC CONDITIONS OF THE CORNEA
A. Post-Inflammatory B. Degenerative (Non-inflammatory)
1. Keratectasia 1. Keratoconus
2. Anterior (corneal) 2. Keratoglobus
staphyloma.
KERATOCONUS (Conical Cornea)
● Gross Pathological changes:
Thickness: The center of the cornea is markedly thin.
normal
keratoconus
2. Shape: conical with apex usually
below and nasal to the corneal center.
Later, the apex becomes opacified
(Acute hydrops).
3. A brown ring surrounds the base of
the cone due to iron deposition in the
epithelial cells (Fleischer's ring)
Acute hydrops in KC
Acute hydrops & Corneal opacity
Post Lasik Ectasia
Chemical injury
Pseudophakic bullous keratopathy
Dry Eye
Thank You

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Corneal Causes of Decreased Vision.pptx