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Fat Soluble Vitamins
Vitamin A
Other Names
Retinol
Retinal
Retinoic acid
Precursors are carotenoids such as beta-
carotene
Vitamin A
Functions
Vision:
- Maintenance of cornea, epithelial cells,
mucous membranes, skin
Bone and tooth growth
Reproduction
Immunity.
Vitamin A
Food Source
Retinol: fortified milk, cheese, cream, butter,
fortified margarine, eggs, liver.
Beta-carotene: spinach and other dark leafy
greens; broccoli, deep orange fruits (apricots,
cantaloupe) and vegetables (squash, carrots,
sweet potatoes, pumpkin)
Vitamin A
Deficiency Disease
Hypovitaminosis A
Deficiency Symptoms
Night blindness
Corneal drying (xerosis), softening of the
cornea (keratomalacia), corneal degeneration
and blindness
Triangular gray spots on eye (Bitot’s spots)
Impaired immunity
Plugging hair follicles with keratin, forming
white lumps (hyperkeratosis)
Vitamin A
Toxicity Disease
Hypervitaminosis A
Toxicity Symptoms
Chronic toxicity
Increased activity of osteoclasts causing reduced
bone density
Liver abnormalities
Birth defects
Acute toxicity
Blurred vision
Nausea, vomiting, vertigo
Headaches, increased pressure inside the skull
mimicking a brain tumor
Vitamin D
Other Names
Calciferol, 1,25-dihydroxy vitamin D (calcitriol)
The animal version is vitamin D3 or
cholecalciferol
The plant version is vitamin D2 or ergocalciferol
Body cholesterol is a precursor
Vitamin D
Recommended Dietary Allowance
Adults: 600 IU/day (19-50 yr)
Adults: 600 IU/day (51-70 yr)
Adults: 800 IU/day (71 + yr)
Upper Level
Adults: 4,000 IU/day
Vitamin D
Functions
Mineralization of bones:
- raises blood calcium and phosphorus by
increasing absorption from digestive tract
- withdrawing calcium from bones
- stimulating retention by kidneys
Vitamin D
Food Sources
Synthesized in the body with the help of sunlight
Fortified milk, margarine, butter, cereals and
chocolate mixes
beef, egg yolk, liver, fatty fish (herring, salmon,
sardines) and their oils
Vitamin D
Deficiency Diseases
Rickets
Osteomalacia
Vitamin D
Rickets in Children Deficiency Symptoms
Inadequate calcification, resulting in
misshapen bones (bowing of legs)
Enlargement of ends of long bones (knees,
wrists).
Deformities of ribs (bowed, with beads or
knobs)
Delayed closing of fontanel, resulting in rapid
enlargement of head
Lax muscles resulting in protrusion of
abdomen
Muscle spasms
Vitamin D
Osteomalacia in Adults Deficiency Symptoms
Loss of calcium resulting in soft, flexible, brittle,
and deformed bones
Progressive weakness
Pain in pelvis, lower back and legs
Vitamin D
Toxicity Disease
Hypervitaminosis D
Toxicity Symptoms
Elevated blood calcium
Calcification of soft tissues (blood vessels,
kidneys, heart, lungs, tissues around joints)
Frequent urination
Vitamin E
Other Names
Alpha-tocopherol
RDA
Adults: 15 mg/day
Upper Limit
Adults: 1,000 mg/day
Vitamin E
Functions
- Antioxidant :
stabilization of cell membranes,
regulation of oxidation reactions,
protection of polyunsaturated fatty acids and
vitamin A
Vitamin E
Food Sources
Polyunsaturated plant oils (margarine, salad
dressings, shortenings)
Leafy green vegetables
Wheat germ and whole grains
Liver, egg yolk, nuts and seeds
Vitamin E
Deficiency Symptoms
Red blood cell damage
Nerve damage
Toxicity Symptoms
Augments the effect of anti-clotting medication
Vitamin K
Other Names
Phylloquinone, menaquinone, menadione,
naphthaquinone
Adequate Intake
Men: 120 µg/day
Women: 90 µg/day
Vitamin K
Function
Synthesis of blood-clotting proteins and bone
proteins
Food Sources
Bacterial synthesis in the digestive tract
Milk, Liver
Leafy green vegetables, cabbage-type
vegetables,
Vitamin K
Deficiency Symptoms
Hemorrhage
Toxicity Symptoms
Unknown

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Vitamins part 2

Editor's Notes

  1. Other Names Retinol Retinal Retinoic acid Precursors are carotenoids such as beta-carotene
  2. Functions Vision Maintenance of cornea, epithelial cells, mucous membranes, skin Bone and tooth growth Reproduction Immunity
  3. Food Source Retinol: fortified milk, cheese, cream, butter, fortified margarine, eggs, liver. Beta-carotene: spinach and other dark leafy greens; broccoli, deep orange fruits (apricots, cantaloupe) and vegetables (squash, carrots, sweet potatoes, pumpkin)
  4. Deficiency Disease Hypovitaminosis A Deficiency Symptoms Night blindness Corneal drying (xerosis) Triangular gray spots on eye (Bitot’s spots) Softening of the cornea (keratomalacia) Corneal degeneration and blindness (xerophthalmai) Impaired immunity Plugging of hair follicies with keratin, forming white lumps (hyperkeratosis)
  5. Toxicity Disease Hypervitaminosis A Chronic Toxicity Symptoms Increased activity of osteoclasts causing reduced bone density Liver abnormalities Birth defects Acute Toxicity Symptoms Blurred vision Nausea, vomiting, vertigo Headaches, increased pressure inside the skull mimicking a brain tumor
  6. Other Names Calciferol, 1,25-dihydroxy vitamin D (calcitriol) The animal version is vitamin D3 or cholecalciferol The plant version is vitamin D2 or ergocalciferol Body cholesterol is a precursor
  7. Adequate Intake Adults: 600 IU/day (19-50 yr) Adults: 600 IU/day (51-70 yr) Adults: 800 IU/day (> 70 yr) Upper Level Adults: 4,000 IU/day
  8. Functions Mineralization of bones (raises blood calcium and phosphorus by increasing absorption from digestive tract, withdrawing calcium from bones, stimulating retention by kidneys)
  9. Food Sources Synthesized in the body with the help of sunlight Fortified milk, margarine, butter, cereals and chocolate mixes Veal, beef, egg yolk, liver, fatty fish (herring, salmon, sardines) and their oils
  10. Deficiency Diseases Rickets Osteomalacia
  11. Rickets in Children Deficiency Symptoms Inadequate calcification, resulting in misshapen bones (bowing of legs) Enlargement of ends of long bones (knees, wrists) Deformities of ribs (bowed, with beads or knobs) Delayed closing of fontanel, resulting in rapid enlargement of head Lax muscles resulting in protrusion of abdomen Muscle spasms
  12. Osteomalacia in Adults Deficiency Symptoms Loss of calcium resulting in soft, flexible, brittle, and deformed bones Progressive weakness Pain in pelvis, lower back and legs
  13. Toxicity Disease Hypervitaminosis D Toxicity Symptoms Elevated blood calcium Calcification of soft tissues (blood vessels, kidneys, heart, lungs, tissues around joints) Frequent urination
  14. Other Names Alpha-tocopherol RDA Adults: 15 mg/day Upper Limit Adults: 1,000 mg/day
  15. Functions Antioxidant (stabilization of cell membranes, regulation of oxidation reactions, protection of polyunsaturated fatty acids and vitamin A
  16. Food Sources Polyunsaturated plan oils (margarine, salad dressings, shortenings Leafy green vegetables Wheat germ and whole grains Liver, egg yolk, nuts and seeds
  17. Deficiency Symptoms Red blood cell breakage Nerve damage Toxicity Symptoms Augments the effect of anti-clotting medication
  18. Other Names Phylloquinone, menaquinone, menadione, naphthaquinone Adequate Intake Men: 120 µg/day Women: 90 µg/day
  19. Function Synthesis of blood-clotting proteins and bone proteins                 Food Sources Bacterial synthesis in the digestive tract Milk, Liver Leafy green vegetables, cabbage-type vegetables
  20. Deficiency Symptoms Hemorrhaging Toxicity Symptoms None known