Contagious disease with high mortality up to 100% that affects cattle and buffalo. Early signs include small pinpoint areas of necrosis on the tongue, gums, and dental pad. Severe ocular discharge may become purulent. Clinical signs include high fever, dullness, depression, and death within 2-3 days in the per acute form. The acute form shows sudden fever, lacrimation, nasal discharge, and congested mucous membranes followed by raised gray or white necrotic foci on the mouth that increase in size and number and may detach, leaving raw erosions.

2. Contagious disease with high mortality up to
100%

3. Small pinpoint areas of necrosis on the ventral
surface of the tongue (early oral lesion(

4. Small pinpoint areas of necrosis on the gum &
dental pad

9. Severe occular discharge which may
become purulent

10. *acute highly contagious viral disease of cattl & buffalo ch`:
-by erosive stomatitis & diarrhea with high mortality &
high morbidity rates
Clinical signs:
1-per acute form → high fever , dullness & depression , death
within 2-3 days (before mucosal erosions(
2-acute form → a- sudden fever , lacrimation , serous nasal
discharge + congested M.M
b- after 2-5 days → raised pin point gray
(white) necrotic foci on M.M of
mouth → ↑in size & number →
coalesce → caseous plagues → detached
→ leaving raw red erosions , the lesion
appear on ventral aspect of tongue ,
dental pad & lips

11. C-profuse salivation
D-purulent occular & nasal discharge
E-profuse watery diarrhea (appear 2-3 days of ↓ of
fever(
*death after 6-12 ays after onset of fever
N.B
*the ch` zebra striping in colon & rectal mucosa
D.D
a-from disease cause erosive stomatitis & diarrhea as:
*Malignant catarral fever (MCV(
*Bovine viral diarrhea-Mucosal disease
complex (BVD-MD(
*Infectious bovine rhinotracheitis (alimentary form(
(IBR(

12. b-from disease cause oral lesion without diarrhea as:
*FMD *Bovine papular stomatitis
*Blue tongue (in sheep & goat(
c-from peste des petits ruminants (PPR( → affect goat &
sheep but cattle are resistant
*very bad prognosis due to high mortality rate
*Treatment : no specific treatment
*Vaccination:
-restriction of animal movement + emergency
vaccination for all infected & contact animal
*Live attenuated vaccine:
-safe for pregnant animal

13. **the vaccine present in lyophilized form in vials (100 & 200
doses) → reconstituted in 100 & 200 ml saline
dose: 1 ml /S.C
*The acquired immunity is transmitted to the offspring via
colostrum & persist for 5-6 monthes so, the starting age of
vaccination in calves at 5-6 month of age
-if no colostrum → vaccination in the 1st
week & revaccinate again
after 6-8 month
-if gives immunity for 1-2 years