3. The liver
T.B. of the liver may arise from:-
a- Congenital infection the umbilical vein.
b- From primary intestinal T.B "the portal l.n. receive afferent
lymph ties from the duodenum"
c- From infected lungs intestines mesenteric liens fine
branches of portal vein.
d- Through hamates genus route.
e- Sec. extension from T.B. of peritoneum , intestine or
mesenteric l.ns "but on the other hand.T.B.of post Mediastinal
l.n. may be due to lymphatic drainage from T.B. liver."
The lesion in cattle are:-
Nodular encapsulated foci or like small encapsulated abscesses.
The lesions in pigs as mention before.
4. The spleen
● T.B. of the spleen of calves congenital inf. the nodules
are present on the surface.
● If the T.B. nodules present in splendid substance This
mean hamates genus spread primary inf. The animal
die before develop of lesion.
● If the lesion are chronic undergo cassation and
calcification .
In pig : T.B. mostly found in the substance of spleen .
This mean tendancy to generalization.
5. The kidney
►T.B. of the kidney mean haematogenous spread.
►T.B. of boviune kidney appear as small isolated nodules
distributed in sub tissues of the kidney involve the
whole of kidney lobules the surface is irregular ,grayish
white in color on section of the kidney subs there is
caseation.
►T.B. (Miliary T.B.) of kidney cortex indicate Acute
generalization.
►T.B. in renal Lns come from T.B. peritoneum by lymph
drainage.
► In Pigs T.B. nodules are very small and few in number
(Difficult to detect)
6. Stomach and intestines
Primary infection of the intestinal tract more common in
swine than in cattle.
►In Cattle:
● Break down from the lungs stomach + Intestine T.B.
nodules and ulcers of the intestinal mucosa are rare
Commonly in mesenteric Lns.
● In Ileum the nodules may coalesce to form ulcers of varying
size (round or oval) covered with grayish mucopurulent
material.
7. Udder
►T.B. of the udder may result from:
a-haematogenous spread.
b-extension from abdominal lesion.
c-the injection of the bacilli via the teats.
►in early stages of the disease:
The T.B. nodules are recognized by their orange color in contrast
to the normal yellowish white color of the udder tissue.
►Then the affection may show in one of the following forms:
1-chronic diffuse granulomatus forms:
8. Udder
►it is most common form of T.B.
●in beginning appear as grayish red orange brown hand, and
glistening nodules.
●L.n. is not affected.
●in advanced cases, there are hand hard nodules at the size
of a fist, projecting form the surrounding interlobular C.T.
caseation
●cut surface has a grayish red of coarse granular surface.
2-disseminating military udder T.B.:
●small fatty nodules show caseation, calcification
●L.ns always affected.
●This form difficult to recognize as in lactating period
9. Udder
It has the same color of udder and projecting
3-Caseous mastitis:
●it appear as a map.
●the nodules are caseatod especially blood spots.
●L.ns are always affected.
10. Bones and joints
In ox: commonly in ribs of vertebrae yellow
granulation tissue especially thinning ratification of the
cortex and spongy tissue of the bone.
In pig: T.B. in bodies and spinal processes of lumber
vert. ischiopubic symphysis and femur.
12. Skin
T.B. of skin hard painless nodules single or multiple varying
in size up to a hens egg.
If multiple appear as a chain on subcut. lymphatic vessels of
limbs, rarely on chest wan and shoulder.
On section there is a fibrous wall enclosing a casco
calcarcous center or dried material like powdered maize or
flake like pellicle.