Viral infections of the skin DIRECT INFECTIONS ON THE SKIN →Molluscum Contagiosum →Wart SKIN MANIFESTATIONS OF SYSTEMIC DISEASES Vesicular:Hand foot mouth disease,chicken pox,HSV 1,2 Non vesicular:Measles,Rubella and other exanthematous rashes.

2. VIRUSES
• Obligate intracellular parasites.
• Structure :central core of nucleic acid
:protective protein coat
:outermost lipoprotein layer {some}
 Classification :> DNA & RNA Viruses

3. Effect of viruses on host cell
• HOST CELL DESTROYED BY LYTIC VIRAL INFECTION
• TRANSIENT DAMAGE TO HOST CELL
• PERSISTANT INFECTION
• REACTIVATION

4. SKIN MANIFESTATIONS
• VESICLES AND PUSTULES
• FOCAL NECROSIS
• RASHES

5. CLASSIFICATION
• DIRECT INFECTIONS ON SKIN
→Molluscum Contagiosum
→Wart
• SKIN MANIFESTATIONS OF SYSTEMIC DISEASES
∑Vesicular:Hand foot mouth disease,chicken
pox,HSV 1,2
∑Non vesicular:Measles,Rubella and other
exanthematous rashes.

6. MOLLUSCUM
CONTAGIOSUM

7. ETIOLOGY
• POX VIRUS
• TRANSMISSION:Contact,Fomites,Sexual

8. Clinical features
• MORPHOLOGY
:Usually multiple
:Pearly white dome shaped papules that are umblicated.
:Under hand lens-mosaic appearance
:Piercing umblicated centre:White cheesy material.
:Pseudoisomorphic phenomenon+
:Koebners phenomenon +
:Henderson’s patterson bodies

11. Sites of predilection
• Face
• Neck
• Trunk
• Thighs
• Eyelids
• Genitals

12. TREATMENT

13. warts

14. Etiology
• Human Papilloma Virus
• Transmission
Direct or indirect contact{nail
biters,shaving,occupational,swimming pool}
Sexual transmission

15. CLINICAL TYPES

16. Verruca vulgaris (common warts)
• Usually asymptomatic
• MORPHOLOGY:single/multiple,circumscribed,firm
papules :verrucous(hyperkeratotic)dry,stippled surface.
• SITES:occur anywhere
:mostly seen on back of hands,fingers,knees
and feet.

19. Palmoplantar warts
• 2 TYPES:>SUPERFICIAL
:>DEEP
SUPERFICIAL
>Usually painless
>Morphology:Hyperkeratotic papules and plaques
consisting of multiple small warts that are tightly packed.
>Sites:Soles & Palms[less]

21. • DEEP
>Painful
>Morphology:hyperkeratotic deep seated papules
,surrounded by horny collar .
:paring colar>wart seen as soft granular brown
papule>punctate black dots .
>Sites:Soles,palms and sides of finges{less}

22. Periuncal wart

23. Verruca plana (plane warts)
• MORPHOLOGY:
>Multiple,slightly elevated,flat smooth papules
>skin colored or darker lesions,erythematous
halo(may be)
>pseudokoebner phenomenon
• SITES:Face and dorsal aspect of hands.

26. Digitate wart

27. Filiform wart
• MORPHOLOGY
>Asymptomatic thin elongated,firm
projections arising from a horny base.
• SITES:Face and Scalp

30. Genital wart
• Condyloma Accuminata
• Protuberant moist,cauliflower like growth
• Frenelum,corona and glans in men & posterior
fourchette in womwn.

32. • COMPLICATIONS
>Secondary infection
>Pregnancy related
>Malignant change
:Buschke –Lowenstein tumor
:Cervical intraepithelial neoplasia

33. DIFFERNETIAL DIAGNOSIS-CORNS

34. MOLLUSCUM CONTAGIOSUM

35. TREATMENT

36. THANK YOU