Products informations

1. Actibon
Calcium Carbonate 500mg elemental with 500 IU Vitamin D3
Dual advantage Calcium & Vitamin D3
Prescribing information: Each film –coated tablet contains Calcium Carbonate 500mg elemental calcium with 500
IU Vitamin D3
INDICATIONS: Treatment of Calcium and Vitamin D deficiency state (pregnancy, lactation, growing children, post
menopausal).
DOSAGE: 1-2 tablets per day or advice by physician.
CONTRAINDICATIONS: Hypercalcaemia e.g. myeloma, bone metastases or other malignant bone diseases, sarcoidosis,
primary hyperparathyroidism, Vitamin D over dosage, severe renal failure and hypersensitivity to any of the ingredients.
Relative contra indications osteoporosis due to prolonged immobilizations, renal stones severe hypercalciuria.
PRECAUTIONS: Supervision required in mild to moderate renal failure or mild hyperciuria, prolonged treatment,
cardiovascular disease, increased risk of Hypercalcaemia, rare hereditary problems of fructose intolerance, glucose-galactose
malabsorption, history of renal stones, dehydration, electrolyte imbalance.
INTERACTIONS: Usually risk of Hypercalcaemia with concurrent use of thiazides, Foods containing oxalic acid phosphate
or phytic acid can reduce calcium absorption. Glucocorticoids, phenytoin or barbiturates can decrease the effect of
Vitamin D Concurrent administration can decrease absorption of etidronate, tetracycline, thyroxine, bisphosphonates,
sodium fluoride, quinolone, iron and can increase absorption of aluminum from intestine. It can increase the action of
cardiac glycosides. Avoid the interacting drugs or food for 1-4 hours of Calcium Carbonate intake.
PREGNANCY: Does is dependent on requirement,
LACTATION: No adverse effects noticed with normal daily recommended amounts in nursing babies.
ADVERSE REACTIONS: More likely when taken in much larger doses (>2000 to 2500mg per day), Constipation,
flatulence, nausea, gastric pain, skin rash, hypercalciuria, Hypercalcaemia rarely seen. Prolonged use can lead to
Vitamin D toxicity.
OVERDOSAGE: Symptom of Hypercalcaemia. If severe treat with loop diuretics, bisphosphonates, dialysis with calcium
free dialysate, calcitonin with or without corticosteroids, trisodium edentate.
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