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CRITERIA FOR SCREENING
Successful Screening
Criteria for test
Criteria for disease
• CRITERIA FOR DISEASE:
- Should be an important health problem (High Prevalence).
- Should have an early asymptomatic stage.
- Natural history should be understood.
- Test should be present to diagnose the disease before sign & symptoms.
- Facilities for confirmation of diagnosis should be available.
- Effective treatment should be present.
- Agreed on policy on whom to treat should be present.
- Good evidence the it reduce mortality and morbidity should be present.
- Expected benefits > Risks and costs.
• Criteria for Test:
- Reliable
- Valid
- Simple and inexpensive
- Very safe
- Acceptable to subjects
- Cost effective
- Exit Strategy
• Exit Strategy:
- Facilities for diagnosis and appropriate treatments should be
available for positive subjects.
- Test should be acceptable to aimed people .
Test should not be:
- Painful
- Unsafe
- Discomforting or embarrassing
• Acceptability:
● Also known as Repeatability, Reducibility & Precision.
● Getting the same results, when the test repeated in same target
individuals in the same settings .
• Reliability:
- Observer variation
- Subject variation (Biological)
- Errors related to technical methods
• Causes of Unreliability:
Observer Variation
Intra Observer Inter- Observer
• Also called within observer variation
- Same observer
- Two measurements
- Same Person
- Different results
• Intra-observer:
• Inter-observer:
Also known as between observer variation
- Same subject
- Different observers
Eg. :- Examination of blood smear for malarial
parasite by two observers
Subject variation
(Biological)
Changes in the
parameters
observed
Variation in how the
patient perceives the
symptoms
Regression to
mean
• Errors related to technical methods :
- Defective Instruments
- Error in calibration
- Faulty reagents
- Test itself might be inappropriate or unreliable
• When the errors are large, repeatability will be reduced, a
single test result may be unreliable.

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CRITERIA FOR SCREENING.pptx

  • 2. Successful Screening Criteria for test Criteria for disease
  • 3. • CRITERIA FOR DISEASE: - Should be an important health problem (High Prevalence). - Should have an early asymptomatic stage. - Natural history should be understood. - Test should be present to diagnose the disease before sign & symptoms. - Facilities for confirmation of diagnosis should be available. - Effective treatment should be present. - Agreed on policy on whom to treat should be present. - Good evidence the it reduce mortality and morbidity should be present. - Expected benefits > Risks and costs.
  • 4. • Criteria for Test: - Reliable - Valid - Simple and inexpensive - Very safe - Acceptable to subjects - Cost effective - Exit Strategy
  • 5. • Exit Strategy: - Facilities for diagnosis and appropriate treatments should be available for positive subjects.
  • 6. - Test should be acceptable to aimed people . Test should not be: - Painful - Unsafe - Discomforting or embarrassing • Acceptability:
  • 7. ● Also known as Repeatability, Reducibility & Precision. ● Getting the same results, when the test repeated in same target individuals in the same settings . • Reliability:
  • 8. - Observer variation - Subject variation (Biological) - Errors related to technical methods • Causes of Unreliability:
  • 10. • Also called within observer variation - Same observer - Two measurements - Same Person - Different results • Intra-observer:
  • 11. • Inter-observer: Also known as between observer variation - Same subject - Different observers Eg. :- Examination of blood smear for malarial parasite by two observers
  • 12. Subject variation (Biological) Changes in the parameters observed Variation in how the patient perceives the symptoms Regression to mean
  • 13. • Errors related to technical methods : - Defective Instruments - Error in calibration - Faulty reagents - Test itself might be inappropriate or unreliable • When the errors are large, repeatability will be reduced, a single test result may be unreliable.