What postulates that the state and activity of a particular region of chromatin depends upon the specific modifications, or combinations of modifications, to the histone tails in that region? It suggests that the pattern of modifications adorning the tails of the core histones contains encoded information governing the properties of the nucleosomes containing them. the DaVinci code the chemiosmotic hypothesis the histone code the genetic code Solution Answer is the histone code. Modifications to the histone proteins which bind to the dna, make the fragment of dna accessible to various enzymes..