It is a physiological process</li></ul>Peri-menopause is a period immediately before and after the menopause.<br />www.freelivedoctor.com<br />
Premature ovarian failure ----- the cessation of menses before the age of 40 years.<br /> Artificial menopause ------ the cessation of menses is secondary to some causes, such as oophorectomy, radiation therapy.<br />www.freelivedoctor.com<br />
Peri-menopausal Period Syndrome<br /><ul><li>peri-menopause accompanied by the symptoms of climacteric, including hot flashes, excessive perspiration, night sweets, depression, agitation, vaginal dryness, insomnia
The basic causes of the climacteric syndrome are a progressive decline in ovarian production on estrogens and other sex hormones</li></ul>www.freelivedoctor.com<br />
Negative Feedback<br />Secretion of estrogens decreased (ovary) <br /> ↓<br />FSH increased (40-45 years old)<br /> ↓<br /> FSH,LH increased(45-50 years old)<br /> ↓<br /> FSH increased 14 times<br /> LH increased 3 times(menopause)<br /> ↓<br />FSH, LH gradually decline (3 years after menopause)<br />www.freelivedoctor.com<br />
Symptoms and signs<br />1. Early Symptoms and signs<br /> <br />1) menstraution disorder<br /><ul><li>Oligomenorrhea--- intervals greater than 35 days.
2) vasomotor symptoms( hot flashes, sweats)<br /><ul><li>oestrogen depletion result in instability in the vessels of the skin.
The hot flashes begins on the chest and spreads quickly over the neck, face and upper limbs which lasts only seconds but may recur many times one day. Sweat often follows hot flashes.</li></ul>www.freelivedoctor.com<br />