Your SlideShare is downloading. ×
0
HEMODYNAMIC DISORDERS
&
THROMBOSIS
Edema
Edema
Normal alveoli
Pulmonary Edema
Fluid in Trachea/Bronchi
Abdominal Ascites
Edematous Brain
Normal Brain
Hyperemia and Congestion
Congestion and Hyperemia
CONGESTION AND HYPEREMIA
Congested Lungs
Acute Pulmonary Congestion
Heart Failure Cells” in Alveoli“
Chronic Pulmonary Congestion
Congested and Enlarged Spleen
Nutmeg Liver
• A descriptive term for a liver with chronic
passive congestion, a hepatopathy due to
cardiac decompensation...
Nutmeg liver
Microscopically, the nutmeg pattern results from congestion
around the central veins, as seen here.
This is usually due to...
• Liver is divided histologically into lobules.
• The center of the lobule is the central vein.
• At the periphery of the ...
• Functionally, the liver can be divided into
three zones, based upon oxygen supply.
• Zone 1 encircles the portal tracts ...
Hemorrhage
• Petechiae measure less than 3 mm.

• Purpura measure 0.3–1 cm.

• Ecchymoses greater than 1 cm.
• Here are petechial
hemorrhages seen
on the epicardium
of the heart.
• Petechiae (pinpoint
hemorrhages)
represent bleedin...
• The blotchy areas of hemorrhage in the skin are
called ecchymoses (singular ecchymosis), or also as
areas of purpura.
• ...
Intracerebral Hemorrhage

Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003.
Intracerebral Hemorrhage
Pericardial Hemorrhage
Hemostasis and Thrombosis
THROMBOSIS -Virchow triad
Thrombus - Morphology
Venous

Arterial
 Arise in arteries

 Arise in deep veins and
superficial veins (popleteal 
Femor...
• These are "lines of Zahn" which are the alternating
pale pink bands of platelets with fibrin and red
bands of RBC's form...
Venous Thrombi: Clinical
Thrombotic Vegetations
Mitral Valve

Photo: Stevens A, Lowe J. Slide atlas of pathology. Mosby, London, 1995.
Abdominal Aortic Aneurysm Thrombus
(Deep Vein Thrombosis (DVT
Plaque with Recent Thrombus
Thrombosis
Outcomes

Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003.
Early Organizing Thrombus
Embolism
Embolization (Embolus(
Thromboembolism of Pulmonary Artery

Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th e...
Infarction
Infarction (Infarct(
(Lung (Left(; Spleen (Right

Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunde...
Pulmonary Infarction
Small Intestine Infarction
Kidney Infarction
(Replaced by Fibrotic Scar (Left
Pale Infarct (Wedge( of Spleen
Thanks
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Hemodynamic disorders, thrombosis and shock (practical pathology)
Upcoming SlideShare
Loading in...5
×

Hemodynamic disorders, thrombosis and shock (practical pathology)

2,375

Published on

Published in: Health & Medicine
0 Comments
6 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
2,375
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
257
Comments
0
Likes
6
Embeds 0
No embeds

No notes for slide

Transcript of "Hemodynamic disorders, thrombosis and shock (practical pathology)"

  1. 1. HEMODYNAMIC DISORDERS & THROMBOSIS
  2. 2. Edema
  3. 3. Edema
  4. 4. Normal alveoli
  5. 5. Pulmonary Edema
  6. 6. Fluid in Trachea/Bronchi
  7. 7. Abdominal Ascites
  8. 8. Edematous Brain
  9. 9. Normal Brain
  10. 10. Hyperemia and Congestion
  11. 11. Congestion and Hyperemia
  12. 12. CONGESTION AND HYPEREMIA
  13. 13. Congested Lungs
  14. 14. Acute Pulmonary Congestion
  15. 15. Heart Failure Cells” in Alveoli“ Chronic Pulmonary Congestion
  16. 16. Congested and Enlarged Spleen
  17. 17. Nutmeg Liver • A descriptive term for a liver with chronic passive congestion, a hepatopathy due to cardiac decompensation and failure. • If the congestion is severe, these changes may be accompanied by haemorrhagic necrosis
  18. 18. Nutmeg liver
  19. 19. Microscopically, the nutmeg pattern results from congestion around the central veins, as seen here. This is usually due to a "right sided" heart failure .
  20. 20. • Liver is divided histologically into lobules. • The center of the lobule is the central vein. • At the periphery of the lobule are portal triads.
  21. 21. • Functionally, the liver can be divided into three zones, based upon oxygen supply. • Zone 1 encircles the portal tracts where the oxygenated blood from hepatic arteries enters. • • Zone 3 is located around central veins, where oxygenation is poor. Zone 2 is located in between.
  22. 22. Hemorrhage
  23. 23. • Petechiae measure less than 3 mm. • Purpura measure 0.3–1 cm. • Ecchymoses greater than 1 cm.
  24. 24. • Here are petechial hemorrhages seen on the epicardium of the heart. • Petechiae (pinpoint hemorrhages) represent bleeding from small vessels and are classically found when a coagulopathy is due to a low platelet count. • They can also appear following sudden hypoxia.
  25. 25. • The blotchy areas of hemorrhage in the skin are called ecchymoses (singular ecchymosis), or also as areas of purpura. • Ecchymoses are larger than petechiae. • They can appear with coagulation disorders.
  26. 26. Intracerebral Hemorrhage Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003.
  27. 27. Intracerebral Hemorrhage
  28. 28. Pericardial Hemorrhage
  29. 29. Hemostasis and Thrombosis
  30. 30. THROMBOSIS -Virchow triad
  31. 31. Thrombus - Morphology Venous Arterial  Arise in arteries  Arise in deep veins and superficial veins (popleteal  Femoral Iliac),  Grow in retrograde fashion (towards the heart)  Antigrade  Forms at site of Endothelial injury (AS), turbulence (aneurysms)  At site of stasis (lower extremities)  Pale/ white  Red / dark  Lines of Zahn  No lines of Zahn
  32. 32. • These are "lines of Zahn" which are the alternating pale pink bands of platelets with fibrin and red bands of RBC's forming a true thrombus.
  33. 33. Venous Thrombi: Clinical
  34. 34. Thrombotic Vegetations Mitral Valve Photo: Stevens A, Lowe J. Slide atlas of pathology. Mosby, London, 1995.
  35. 35. Abdominal Aortic Aneurysm Thrombus
  36. 36. (Deep Vein Thrombosis (DVT
  37. 37. Plaque with Recent Thrombus
  38. 38. Thrombosis Outcomes Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003.
  39. 39. Early Organizing Thrombus
  40. 40. Embolism
  41. 41. Embolization (Embolus( Thromboembolism of Pulmonary Artery Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003; . Stevens A, Lowe J. Slide atlas of pathology. Mosby, London, 1995.
  42. 42. Infarction
  43. 43. Infarction (Infarct( (Lung (Left(; Spleen (Right Photo: Kumar, Cotran, Robbins. Robbins Basic pathology, 7 th ed., Saunders, Philadelphia, 2003.
  44. 44. Pulmonary Infarction
  45. 45. Small Intestine Infarction
  46. 46. Kidney Infarction (Replaced by Fibrotic Scar (Left
  47. 47. Pale Infarct (Wedge( of Spleen
  48. 48. Thanks
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×