Online bioscience course for grades 6-12 Fall 2009 bio 1.0
Class mechanics… <ul><li>Attend the online Office Hour on Tuesdays at 3 PM  </li></ul><ul><li>via  tokbox-Discuss previous...
Lecture 6: Organs, tissues  and organisms bio 1.0
Take Homes: <ul><li>Multicellularity </li></ul><ul><li>II.  Organs and tissues: structure and composition </li></ul><ul><l...
Dictyostelium  is attracted to cAMP: http:// www.dnatube.com/view_video.php?viewkey =217686ba124d7356686c bio 1.0
Dictyostelium  moves toward cAMP Using its cytoskeleton: http:// dictybase.org/Multimedia/motility/motility.htm bio 1.0
Dictyostelium  as a model for single cells “going”  multiclellular: http:// en.wikipedia.org/wiki/Dictyostelium “ stressed...
Dictyostelium  single cells assemble  Into a multicellular “slug”: http:// www.youtube.com/watch?v =518MhtVBJho bio 1.0
The evolutionary basis of  multicellularity: http:// www.youtube.com/watch?v = JVqxyYBuI_U bio 1.0
Take Home I Organisms are collections of cells organized into tissues and organs… Multicellularity bio 1.0
The worm  Caenorhabditis elegans- 700 cells make all of the tissues and  organs: bio 1.0
The cells that make-up tissues and  organs are specialized structurally  and compositionally: bio 1.0
Muscle Structure and Function: http:// www.youtube.com/watch?v = ren_IQPOhJc bio 1.0
Three Types of Muscle: http:// www.youtube.com/watch?v =PJDrR3sZPZU bio 1.0
Incredible Human Machine- knowledge on muscle & bone  movement: http:// www.youtube.com/watch?v =7Rzi7zYlWno bio 1.0
Take Home II Organisms are made-up of many cells, which are made-up of many specialized proteins organized into specialize...
Various types of actin proteins form  filaments in different types of  muscle: bio 1.0
Measuring RNA expression using  Expressed Sequence Tags (ESTs) : bio 1.0
Actin gene mRNA expression in  different types of muscle : bio 1.0
Measuring protein expression using  antibodies and tissue arrays: bio 1.0
Actin protein expression in different  muscle tissues: bio 1.0
Take Home III Differential expression of genes govern the protein structure, composition and thus function of cells in tis...
Caenorhabditis elegans “fate map”: bio 1.0
Tagging a gene with GFP: bio 1.0
In the Beginning... There Was  C. Elegans : http:// www.youtube.com/watch?v =M6_0zjEzF6g bio 1.0
Fluorescent C. elegans  nervous system: http:// www.youtube.com/watch?v =LuBF6S6qKas bio 1.0
Take Home IV Tissues and organs form from the egg through the processes of cellular differentiation and development, both ...
Genes program development: http:// www.youtube.com/watch?v =Oc4FAg2I_Z4 bio 1.0
Using our knowledge about genes  and development to make a  “ dinochicken”: http:// www.youtube.com/watch?v =AeYhUUFDiF8 b...
Take Home V The fundamental body plan and structure of an organism can be manipulated at the genetic level, and provides w...
Next Week: Physiology How the cells in tissues and organs function to make organisms work… bio 1.0
instructor Mark E Minie PhD [email_address]   bio 1.0
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Lecture 6 Organs Tissues And Organisms

  1. 1. Online bioscience course for grades 6-12 Fall 2009 bio 1.0
  2. 2. Class mechanics… <ul><li>Attend the online Office Hour on Tuesdays at 3 PM </li></ul><ul><li>via tokbox-Discuss previous week’s video lecture </li></ul><ul><li>Online video lecture e-mailed every Wednesday-view </li></ul><ul><li>lecture and prepare to discuss the following Tuesday </li></ul><ul><li>Comment on video lecture using website discussion </li></ul><ul><li>board </li></ul><ul><li>Online Final Exam given 12/9/2009 </li></ul>bio 1.0
  3. 3. Lecture 6: Organs, tissues and organisms bio 1.0
  4. 4. Take Homes: <ul><li>Multicellularity </li></ul><ul><li>II. Organs and tissues: structure and composition </li></ul><ul><li>III. Organs and tissues: genes determine structure </li></ul><ul><li>and composition </li></ul><ul><li>IV. Differentiation and development </li></ul><ul><li>V. Organisms </li></ul>bio 1.0
  5. 5. Dictyostelium is attracted to cAMP: http:// www.dnatube.com/view_video.php?viewkey =217686ba124d7356686c bio 1.0
  6. 6. Dictyostelium moves toward cAMP Using its cytoskeleton: http:// dictybase.org/Multimedia/motility/motility.htm bio 1.0
  7. 7. Dictyostelium as a model for single cells “going” multiclellular: http:// en.wikipedia.org/wiki/Dictyostelium “ stressed” founder cell secretes cAMP, inducing aggregation Streaming spiral formation bio 1.0
  8. 8. Dictyostelium single cells assemble Into a multicellular “slug”: http:// www.youtube.com/watch?v =518MhtVBJho bio 1.0
  9. 9. The evolutionary basis of multicellularity: http:// www.youtube.com/watch?v = JVqxyYBuI_U bio 1.0
  10. 10. Take Home I Organisms are collections of cells organized into tissues and organs… Multicellularity bio 1.0
  11. 11. The worm Caenorhabditis elegans- 700 cells make all of the tissues and organs: bio 1.0
  12. 12. The cells that make-up tissues and organs are specialized structurally and compositionally: bio 1.0
  13. 13. Muscle Structure and Function: http:// www.youtube.com/watch?v = ren_IQPOhJc bio 1.0
  14. 14. Three Types of Muscle: http:// www.youtube.com/watch?v =PJDrR3sZPZU bio 1.0
  15. 15. Incredible Human Machine- knowledge on muscle & bone movement: http:// www.youtube.com/watch?v =7Rzi7zYlWno bio 1.0
  16. 16. Take Home II Organisms are made-up of many cells, which are made-up of many specialized proteins organized into specialized structures according to function… Organs and tissues: structure and composition bio 1.0
  17. 17. Various types of actin proteins form filaments in different types of muscle: bio 1.0
  18. 18. Measuring RNA expression using Expressed Sequence Tags (ESTs) : bio 1.0
  19. 19. Actin gene mRNA expression in different types of muscle : bio 1.0
  20. 20. Measuring protein expression using antibodies and tissue arrays: bio 1.0
  21. 21. Actin protein expression in different muscle tissues: bio 1.0
  22. 22. Take Home III Differential expression of genes govern the protein structure, composition and thus function of cells in tissues and organs… Organs and tissues: genes determine structure and composition bio 1.0
  23. 23. Caenorhabditis elegans “fate map”: bio 1.0
  24. 24. Tagging a gene with GFP: bio 1.0
  25. 25. In the Beginning... There Was C. Elegans : http:// www.youtube.com/watch?v =M6_0zjEzF6g bio 1.0
  26. 26. Fluorescent C. elegans nervous system: http:// www.youtube.com/watch?v =LuBF6S6qKas bio 1.0
  27. 27. Take Home IV Tissues and organs form from the egg through the processes of cellular differentiation and development, both of which are controlled by genes… Differentiation and development bio 1.0
  28. 28. Genes program development: http:// www.youtube.com/watch?v =Oc4FAg2I_Z4 bio 1.0
  29. 29. Using our knowledge about genes and development to make a “ dinochicken”: http:// www.youtube.com/watch?v =AeYhUUFDiF8 bio 1.0
  30. 30. Take Home V The fundamental body plan and structure of an organism can be manipulated at the genetic level, and provides ways of testing ideas about evolution… Organisms bio 1.0
  31. 31. Next Week: Physiology How the cells in tissues and organs function to make organisms work… bio 1.0
  32. 32. instructor Mark E Minie PhD [email_address] bio 1.0

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