Online bioscience course for grades 6-12 Fall 2009 bio 1.0
Class mechanics… <ul><li>Attend the online Office Hour on Tuesdays at 3 PM  </li></ul><ul><li>via  tokbox-Discuss previous...
Final Exam: <ul><li>Online form </li></ul><ul><li>Link will be e-mailed by 12 noon 12/18/2009 </li></ul><ul><li>One hour t...
Lecture 10: Computers and biology bio 1.0
Ultra-realistic simulation: Viral DNA packing process… http://www.dnatube.com/video/1232/Viral-DNA-Packaging--Part-I Viral...
Take Homes: <ul><li>Computational biology and bioinformatics </li></ul><ul><li>II.  Biological databases </li></ul><ul><li...
http:// en.wikipedia.org/wiki/Computational_biology bio 1.0
http:// en.wikipedia.org/wiki/Bioinformatics bio 1.0
Sequencing of the human genome  was made possible by computing: Human genome sequencing-Animated tutorial http:// www.yout...
Take Home I Computational biology and bioinformatics The application of Information Technology to studying biological syst...
Biological databases: bio 1.0 BLAST Text Centric ENTREZ Sequence Centric Literature Databases Molecular Databases Genome D...
National Center for Biological  Information (NCBI)-an overview: http:// www.youtube.com/watch?v =X7s1zewqeLI Tutorial: Ove...
National Center for Biological  Information (NCBI)-a protein: http:// www.youtube.com/watch?v =gnc2qUcmhWE Tutorial: Exami...
The Kyoto Encyclopedia of Genes  and Genomes (KEGG): Tutorial: Overview of KEGG Bioinformatics Website  http:// www.youtub...
University of California Santa Cruze  (UCSC) Genome Browser: BIT 1.1 UCSC Genome Browser: Getting DNA Sequence http:// www...
Take Home II Data ranging from DNA sequences of bacterial, viral, animal and plant DNA to protein structural data to imagi...
Programming languages for biology- Practical Extraction and Reporting  Language (PERL): http:// en.wikipedia.org/wiki/Perl...
Get PERL: http:// www.perl.org / bio 1.0
BioPERL: http:// en.wikipedia.org/wiki/BioPerl bio 1.0
Take Home III Programming has become a required skill in biology, and the scripting language PERL (Practical Extraction an...
Biological animation: http:// www.youtube.com/watch?v =2fHuJMnDUPI bio 1.0
Swine Flu - Pandemic Flu  Simulation Model: http:// www.youtube.com/watch?v =htnh7pBBtrM bio 1.0
Biology and video games: http:// www.youtube.com/watch?v =KTRV4FKDNvo bio 1.0
Take Home IV Computers have revolutionized our understanding of biology through animations and simulations modeling biolog...
Synthetic biology video: http:// www.youtube.com/watch?v =PCxSa6vGEFY bio 1.0
International Genetically  Engineered Machines (iGEM): http:// en.wikipedia.org/wiki/Igem bio 1.0
2009 iGEM competition: Edinburgh iGEM 2009 - MINEBUSTERS http:// www.youtube.com/watch?v =QLsmjL3RIKw bio 1.0
UW iGEM: BioBrick-A-Bot Model C V 1.1 http:// www.youtube.com/watch?v =FRijFX0BpGI bio 1.0
Take Home V Synthetic biology involves applying the concepts of computer hardware and software design and implementation t...
Thanks! bio 1.0
instructor Mark E Minie PhD [email_address]   bio 1.0
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Lecture 10 Computers In Biology

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Lecture 10 Computers In Biology

  1. 1. Online bioscience course for grades 6-12 Fall 2009 bio 1.0
  2. 2. Class mechanics… <ul><li>Attend the online Office Hour on Tuesdays at 3 PM </li></ul><ul><li>via tokbox-Discuss previous week’s video lecture </li></ul><ul><li>Online video lecture e-mailed every Wednesday-view </li></ul><ul><li>lecture and prepare to discuss the following Tuesday </li></ul><ul><li>Comment on video lecture using website discussion </li></ul><ul><li>board </li></ul><ul><li>Online Final Exam given 12/18/2009 </li></ul>bio 1.0
  3. 3. Final Exam: <ul><li>Online form </li></ul><ul><li>Link will be e-mailed by 12 noon 12/18/2009 </li></ul><ul><li>One hour to complete-finish no later than 12 noon 12/19/2009 </li></ul><ul><li>Will cover all 10 lectures… </li></ul><ul><li>“ Honor System”… </li></ul>bio 1.0
  4. 4. Lecture 10: Computers and biology bio 1.0
  5. 5. Ultra-realistic simulation: Viral DNA packing process… http://www.dnatube.com/video/1232/Viral-DNA-Packaging--Part-I Viral DNA Packaging - Part II http://www.dnatube.com/video/1233/Viral-DNA-Packaging--Part-II bio 1.0
  6. 6. Take Homes: <ul><li>Computational biology and bioinformatics </li></ul><ul><li>II. Biological databases </li></ul><ul><li>III. Programming </li></ul><ul><li>IV. Modeling and simulation </li></ul><ul><li>V. Synthetic biology </li></ul>bio 1.0
  7. 7. http:// en.wikipedia.org/wiki/Computational_biology bio 1.0
  8. 8. http:// en.wikipedia.org/wiki/Bioinformatics bio 1.0
  9. 9. Sequencing of the human genome was made possible by computing: Human genome sequencing-Animated tutorial http:// www.youtube.com/watch?v =-gVh3z6MwdU Shotgun sequencing http:// www.youtube.com/watch?v =vg7Y5EeZsjk bio 1.0
  10. 10. Take Home I Computational biology and bioinformatics The application of Information Technology to studying biological systems has led to the development of two new areas of research-Computational biology and bioinformatics… bio 1.0
  11. 11. Biological databases: bio 1.0 BLAST Text Centric ENTREZ Sequence Centric Literature Databases Molecular Databases Genome Databases External NIH External non-NIH NCBI BioDataSpace http://www.ncbi.nlm.nih.gov / BioDataSpace <ul><li>ENTREZ Genome </li></ul><ul><li>ENTREZ Genome Project </li></ul><ul><li>Map Viewer </li></ul><ul><li>Cancer Chromosomes </li></ul><ul><li>SKY/M-FISH & CGH </li></ul><ul><li>Nucleotide Sequences </li></ul><ul><li>Protein Sequences </li></ul><ul><li>Structures </li></ul><ul><li>Genes </li></ul><ul><li>Gene Expression </li></ul><ul><li>Taxonomy </li></ul><ul><li>PubMed </li></ul><ul><li>PubMed Central </li></ul><ul><li>OMIM </li></ul><ul><li>Books </li></ul><ul><li>CGAP </li></ul><ul><li>UCSC </li></ul><ul><li>e! </li></ul><ul><li>GDB </li></ul><ul><li>MGC </li></ul>BLink
  12. 12. National Center for Biological Information (NCBI)-an overview: http:// www.youtube.com/watch?v =X7s1zewqeLI Tutorial: Overview of the NCBI Bioinformatics Website bio 1.0
  13. 13. National Center for Biological Information (NCBI)-a protein: http:// www.youtube.com/watch?v =gnc2qUcmhWE Tutorial: Examining the 3D Structure of Rhodopsin at NCBI bio 1.0
  14. 14. The Kyoto Encyclopedia of Genes and Genomes (KEGG): Tutorial: Overview of KEGG Bioinformatics Website http:// www.youtube.com/watch?v =mGS0n8aJu5o bio 1.0
  15. 15. University of California Santa Cruze (UCSC) Genome Browser: BIT 1.1 UCSC Genome Browser: Getting DNA Sequence http:// www.youtube.com/watch?v =ehIH-rpQoQ4 bio 1.0
  16. 16. Take Home II Data ranging from DNA sequences of bacterial, viral, animal and plant DNA to protein structural data to imaging data are all stored on Web based databases… Biological databases bio 1.0
  17. 17. Programming languages for biology- Practical Extraction and Reporting Language (PERL): http:// en.wikipedia.org/wiki/Perl bio 1.0
  18. 18. Get PERL: http:// www.perl.org / bio 1.0
  19. 19. BioPERL: http:// en.wikipedia.org/wiki/BioPerl bio 1.0
  20. 20. Take Home III Programming has become a required skill in biology, and the scripting language PERL (Practical Extraction and Reporting Language ) is currently the most commonly used tool… Programming bio 1.0
  21. 21. Biological animation: http:// www.youtube.com/watch?v =2fHuJMnDUPI bio 1.0
  22. 22. Swine Flu - Pandemic Flu Simulation Model: http:// www.youtube.com/watch?v =htnh7pBBtrM bio 1.0
  23. 23. Biology and video games: http:// www.youtube.com/watch?v =KTRV4FKDNvo bio 1.0
  24. 24. Take Home IV Computers have revolutionized our understanding of biology through animations and simulations modeling biological processes… Modeling and simulation bio 1.0
  25. 25. Synthetic biology video: http:// www.youtube.com/watch?v =PCxSa6vGEFY bio 1.0
  26. 26. International Genetically Engineered Machines (iGEM): http:// en.wikipedia.org/wiki/Igem bio 1.0
  27. 27. 2009 iGEM competition: Edinburgh iGEM 2009 - MINEBUSTERS http:// www.youtube.com/watch?v =QLsmjL3RIKw bio 1.0
  28. 28. UW iGEM: BioBrick-A-Bot Model C V 1.1 http:// www.youtube.com/watch?v =FRijFX0BpGI bio 1.0
  29. 29. Take Home V Synthetic biology involves applying the concepts of computer hardware and software design and implementation to biology…the annual iGEM competition involves students from many nations developing “bio-gadgets”… Synthetic biology bio 1.0
  30. 30. Thanks! bio 1.0
  31. 31. instructor Mark E Minie PhD [email_address] bio 1.0

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